SharpBrains

Today we are fortunate to interview Dr. Jerri Edwards, an Associate Professor at University of South Florida's School of Aging Studies and Co-Investigator of the influencial ACTIVE study. Dr. Edwards was trained by Dr. Karlene K. Ball, and her research is aimed toward discovering how cognitive abilities can be maintained and even enhanced with advancing age.

Main focus of research

Alvaro Fernandez: Please explain to our readers your main research areas

Jerri Edwards: I am particularly interested in how cognitive interventions may help older adults to avoid or at least delay functional difficulties and thereby maintain their independence longer. Much of my work has focused on the functional ability of driving including assessing driving fitness among older adults and remediation of cognitive decline that results in driving difficulties.

Some research questions that interest me include, how can we maintain healthier lives longer? How can training improve cognitive abilities, both to improve those abilities and also to slow-down, or delay, cognitive decline? The specific cognitive ability that I have studied the most is processing speed, which is one of the cognitive skills that decline early on as we age.

ACTIVE results

Can you explain what cognitive processing speed is, and why it is relevant to our daily lives?

Processing speed is mental quickness. Just like a computer with a 486 processor can do a lot of the same things as a computer with a Pentium 4 processor, but it takes much longer, our minds tend to slow down with age as compared to when we were younger. We can do the same tasks, but it takes more time. Quick speed of processing is important for Continue Reading »

Dr. Robert Sylwester is an educator of educators, having received multiple awards during his long career as a master communicator of the implications of brain science research for education and learning. He is the author of several books and many journal articles, and member of our Scientific Advisory Board. His most recent book is The Adolescent Brain: Reaching for Autonomy (Corwin Press, 2007). He is an Emeritus Professor of Education at the University of Oregon.

I am honored to interview him today.

Alvaro Fernandez: Let's start with that eternal source of debate. What do we know about the respective roles of genes and our environment in brain development?

Robert Sylwester: Genetic and environmental factors both contribute to brain maturation. Genetics probably play a stronger role in the early years, and the environment plays a stronger role in later years. Still the mother's (environmental) use of drugs during the pregnancy could affect the genetics of fetal brain development, and some adult illnesses, such as Huntington's Disease, are genetically triggered.

Nature and nurture both require the significant contributions of the other in most developmental and maintenance functions. We typically think of environmental factors as things that happen to us, over which we have little control.

Can't our own decisions have an effect in our own brain development? For example, what if I choose a career in investment banking, vs. one in journalism or teaching?

We make our own career decisions in life, and most of us make a combination of good and bad decisions, which influence our brain's maturation.

My father was very unusual in his career trajectory in that he worked at one place throughout his entire adult life, and died three months after he retired at 91. I've always thought that it's a good idea to make a change every ten years or so and do something different – either within the same organization or to move to another one.

It's just as good for organizations to have some staff turnover as it is for staff to move to new challenges. The time to leave one position for another is while you and your employer are Continue Reading »

Sharon Begley, Newsweek’s science reporter, recently wrote that

- “With the nation’s 78 million baby boomers approaching the age of those dreaded “where did I leave my keys?” moments, it’s no wonder the market for computer-based brain training has shot up from essentially zero in 2005 to $80 million this year, according to the consulting firm SharpBrains.”

- “Now comes the largest and most rigorous study of a commercially-available training program, and it shows that there is hope for aging brains. This morning, at the meeting of the Gerontological Society of America, scientists are presenting data showing that after eight weeks of daily one-hour sessions with Brain Fitness 2.0 from Posit Science, elderly volunteers got measurably better in their brain’s speed and accuracy of processing. “

We recently had the chance to interview Dr. Elizabeth Zelinski of the University of Southern California Andrus Gerontology Center, who led the IMPACT (Improvement in Memory with Plasticity-based Adaptive Cognitive Training) Study Sharon Begley refers to in the quote above. 

First, some context on this study, which is by far the largest high-quality study of its kind. The study was prospective, randomized, controlled, and used a double blind trial. 524 healthy adults 65-year-old and over were divided into two groups. One received an hour a day of training for eight to ten weeks, and the other spent the same amount of time watching educational DVDs. The IMPACT study, funded by Posit Science corporation, was performed in multiple locations, including the Mayo Clinic, USCF, and San Francisco Veteran Affairs Medical Center.

The discussion centers at his point on the initial results that were presented Gerontological Society of America (the study hasn't been published yet).

Alvaro Fernandez: Dr. Zelinski. Thank you for being with us. Could you start by setting the context and providing an overview of how human cognitive abilities typically evolve as we age – based on insights from your Long Beach Longitudinal Study?

Elizabeth Zelinski: Of course. The first concept to understand is that different cognitive skills evolve over the lifespan in different ways. Some that rely on experience, such as vocabulary, actually improve as we age. Some tend to decline gradually, starting in our late 20s. This happens, for example, with processing speed (how long it takes us to process and respond to information), memory, and reasoning. We could summarize this phenomenon by saying that as we age we get better at dealing with the familiar, but worse at dealing with the new. We can always learn, but at a slower pace.

Are there any specific tipping or inflection points in this trend, any age when the rate of decline is more pronounced?

We don’t have a clear answer to that. It depends a lot on the individual. In general it is a gradual, cumulative process, so that by age 70 we statistically see clear age declines. Which, for example, is a strong factor determining why older adults struggle to adapt to new technologies, but why trying to learn them provides needed mental stimulation. Now we know that genes only account for a portion of this decline. Much of it depends on our environment, lifestyle and actions.

Can you summarize what a healthy individual can do to slow down this process of decline, and help stay healthy and productive as long as possible?

One general recommendation is to do everything we can to prevent or delay disease processes, such as diabetes or high-blood pressure, that have a negative effect on our brains. For example, it is a tragedy in our society that we usually reduce our levels of physical exercise drastically after we leave school.

Let me then ask: what are the relative virtues of physical vs. mental exercise?

Great question! That in fact leads into my second recommendation. Aerobic exercise has been shown to Continue Reading »

(Dear reader: Here you have a little gift to continue the Thanksgiving spirit. Enjoy the interview, and thank you for visiting our site.)

Prof. Robert Emmons studies gratitude for a living as Professor of Psychology at UC Davis and is Editor-In-Chief of the Journal of Positive Psychology. He has just published Thanks: How the New Science of Gratitude Can Make You Happier, an interdisciplinary book that provides a research-based synthesis of the topic as well as practical suggestions.

Alvaro Fernandez: Welcome. Prof. Emmons, could you please provide us an overview of the Positive Psychology field so we understand the context for your research?

Robert Emmons: Sure. Martin Seligman and colleagues launched what was called “positive psychology” in the late 90s as an antidote to the traditional nearly exclusive emphasis of “negative psychology” focused on fixing problems like trauma, addiction, and stress. We want to balance our focus and be able to help everyone, including high-functioning individuals. A number of researchers were investigating the field since the late 80s, but Seligman provided a new umbrella, a new category, with credibility, organized networks and funding opportunities for the whole field.

And where does your own research fit into this overall picture?

I have been researching gratitude for almost 10 years. Gratitude is a positive emotion that has traditionally been the realm of humanists and philosophers, and only recently the subject of a more scientific approach. We study gratitude not as a merely academic discipline, but as a practical framework to better functioning in life by taking control of happiness levels and practicing the skill of emotional self-regulation.

What are the 3 key messages that you would like readers to take away from your book?

First, the practice of gratitude can increase happiness levels by around 25%. Second, this is not hard to achieve - a few hours writing a gratitude journal over 3 weeks can create an effect that lasts 6 months if not more. Third, that cultivating gratitude brings other health effects, such as longer and better quality sleep time.

What are some ways to practice gratitude, and what benefits could we expect? Please refer to your 2003 paper in the Journal of Personality and Social Psychology, where I found fascinating quotes such as that “The ability to notice, appreciate, and savior the elements of one’s life has been viewed as a crucial element of well-being.”

The most common method we use in our research is to ask people to keep a “Gratitude Journal” where you write something you feel grateful for. Doing so 4 times a week, for as little as 3 weeks, is often enough to create a meaningful difference in one’s level of happiness. Another exercise is to write a “Gratitude Letter” to a person who has exerted a positive influence on one’s life but whom we have not properly thanked in the past, and then to meet that person and read the letter to them face to face.

The benefits seem to be very similar using both methods in terms of enhanced happiness, health and wellbeing. Most of the outcomes are self-reported, but there is an increasing emphasis on measuring objective data such as cortisol and stress levels, heart rate variability, and even brain activation patterns. The work of Richard Davidson is exemplary in that respect, showing how mindfulness practice can rewire some activation patterns in Continue Reading »

Just came accross an excellent Interview with Carol Dweck. Thank you Coert! 

Carol Dweck is a professor of Psychology at Stanford University. Last year she published a great book called Mindset: The New Psychology of Success, where she elaborates on her (and ours) key message: the way you view your own intelligence largely determines how it will develop. And no matter how you define "intelligence". In this interview Coert asks Carol Dweck about the book and about what the practical implications of her work are for managers. See a couple of quotes below:

- "In my book I identify two mindsets that play important roles in people's success. In one, the fixed mindset, people believe that their talents and abilities are fixed traits. They have a certain amount and that's that; nothing can be done to change it. Many years of research have now shown that when people adopt the fixed mindset, it can limit their success. They become over-concerned with proving their talents and abilities, hiding deficiencies, and reacting defensively to mistakes or setbacks-because deficiencies and mistakes imply a (permanent) lack of talent or ability. People in this mindset will actually pass up important opportunities to learn and grow if there is a risk of unmasking weaknesses. This is not a recipe for success in business, as ultimately shown by the folks at Enron, who rarely admitted any mistakes. What is the alternative?"
- "In the other mindset, the growth mindset, people believe that their talents and abilities can be developed through passion, education, and persistence. For them, it's not about looking smart or grooming their image. It's about a commitment to learning--taking informed risks and learning from the results, surrounding yourself with people who will challenge you to grow, looking frankly at your deficiencies and seeking to remedy them. Most great business leaders have had this mindset, because building and maintaining excellent organizations in the face of constant change requires it."

Enjoy the whole Interview with Carol Dweck
 

And this related blog post, where we posited that "In short: there is much that each of us can do to improve our brain fitness, no matter our age, occupation or starting point. There are some fundamental capacities that we can train. And we have to care for good physical exercise and stress management on top of mental exercise."

Last Monday, NPR (very good US-based radio station) had a program on "do brain training programs work?" that reflected very old-fashioned thinking. In short, the guest speakers talked and talked about the importance of nutrition and physical exercise (both very important, as we have covered in this blog multiple times), and expressed skepticism about the concept of exercising our brains to improve attention, memory and other skills...I guess it takes a while to change old mental paradigms (And yes, some programs work better than others).

Neuroscientists have finally debunked that old thinking that our brains decline inexorably after a certain age with little each of us can do to "exercise" or "train our brains". But don't trust me. During the last year I have had the fortune to interview 11 cutting-edge neuroscientists and cognitive psychologists on their research and thoughts. Here are some of my favorite quotes (you can read the full interview notes by clicking the links):

 "Today, thanks to fMRI and other neuroimaging techniques, we are starting to understand the impact our actions can have on specific parts of the brain."- Dr. Judith S. Beck, Director of the Beck Institute for Cognitive Therapy and Research, and author of The Beck Diet Solution: Train Your Brain to Think Like a Thin Person. Full Interview Notes.

“Learning is physical. Learning means the modification, growth, and pruning of our neurons, connections–called synapses– and neuronal networks, through experience...When we do so, we are cultivating our own neuronal networks. We become our own gardeners”- Dr. James Zull, Professor of Biology and Biochemistry at Case Western University. Full Interview Notes.

“Exercising our brains systematically is as important as exercising our bodies. In my experience, “Use it or lose it” should really be “Use it and get more of it”.- Dr. Elkhonon Goldberg, neuropsychologist, clinical professor of neurology at New York University School of Medicine, and disciple of the great neuropsychologist Alexander Luria. Full Interview Notes.

“What research has shown is that cognition, or what we call thinking and performance, is really a set of skills that we can train systematically. And that computer-based cognitive trainers or “cognitive simulations” are the most effective and efficient way to do so.” - Dr. Daniel Gopher, Director of the Research Center for Work Safety and Human Engineering at Technion Institute of Science. Full Interview Notes.

“Individuals who lead mentally stimulating lives, through education, occupation and leisure activities, have reduced risk of developing Alzheimer’s symptoms. Studies suggest that they have 35-40% less risk of manifesting the disease”- Dr. Yaakov Stern, Division Leader of the Cognitive Neuroscience Division of the Sergievsky Center at the College of Physicians and Surgeons of Columbia University, New York. Full Interview Notes.

"It is hardly deniable that brains enchant Japanese people. We love brain training. Dentsu, the biggest advertising agency, announced the No.1 Consumer-chosen 2006 Product was game software and books for brain training."- Go Hirano, Japanese executive, founder of NeuWell. Full Interview Notes.

“Elite performers are distinguished by the structuring of their learning process… It is important to understand the role of emotions: they are not “bad”. They are very useful signals. It is important to become aware of them to avoid being engulfed by them, and learn how to manage them.” - Dr. Brett Steenbarger, Associate Professor of Psychiatry and Behavioral Sciences, SUNY Medical University, and author of Enhancing Trader Performance. Full Interview Notes.

“We have shown that working memory can be improved by training...I think that we are seeing the beginning of a new era of computerized training for a wide range of applications” – Dr. Torkel Klingberg, Director of the Developmental Cognitive Neuroscience Lab at Karolinska Institute. Full Interview Notes.

“Training is very important: attentional control is one of the last cognitive abilities to develop in normal brain development...I can easily see the relevance in 2 fields. One, professional sports. Two, military training.”  Professor Bradley Gibson is the Director of the Perception and Attention Lab at University of Notre Dame. Full Interview Notes.

“I don't see that schools are applying the best knowledge of how minds work. Schools should be the best place for applied neuroscience, taking the latest advances in cognitive research and applying it to the job of educating minds.” - Dr. Arthur Lavin, Associate Clinical Professor of Pediatrics at Case Western School of Medicine, pediatrician in private practice. Full Interview Notes.

“Cognitive training rests on solid premises, and some programs already have very promising research results. Some of the most are promising areas are: neurofeedback, which as a whole is starting to present good research results, and working memory training.” - Professor David Rabiner, Senior Research Scientist and the Director of Psychology and Neuroscience Undergraduate Studies at Duke University: Full Interview Notes.

There is much we can do everyday to literally exercise our brains. No matter our age. So much to Learn...so Good to Learn! Let's see when this story makes it into NPR.