(Editor’s Note: we are pleased to bring you this article thanks to our collaboration with Greater Good Magazine).

100 is the New 65
- Why do some people live to 100? Researchers are trying to find out, reports Meera Lee Sethi, and they’re discovering how we might live better lives, not just longer ones.

Will Clark, 105, recently bought a van for a 5,000-mile road trip across the Midwest with his wife, Lois, who is 102.

Elsa Brehm Hoffmann loves bridge and is always ready for a party. Rosa McGee enjoys singing hymns to herself all day long. Will Clark makes a mean spaghetti and meatballs. What connects these three? They belong to the single fastest growing segment of the United States population: people over a hundred years old.

Hoffmann, McGee, Clark, and the nearly 100,000 other centenarians in the U.S. provide inspiration to the rest of us. But they also provide researchers with a tantalizing puzzle: Why do some people live so long? For years, medical researchers have been studying this select group, identifying some key factors to a long life. Now, a growing body of research is suggesting that longevity isn’t just linked to good genes and a healthy lifestyle; it’s also tied to cultivating a positive, resilient attitude toward life. These results validate a simple idea: that centenarians can teach us how to live not just longer lives, but better ones.

At the fore of this research is the New England Centenarian Study (NECS), which has enrolled more than 1,500 centenarians from around the world over the past 15 years. The study’s director, Thomas Perls, says these participants dispel the belief that the older someone gets, the sicker he or she becomes. Instead, he says, “the older you get, the healthier you’ve been.” In other words, people who demonstrate exceptional longevity tend to have had a lifelong history of good health.

Indeed, people who die in their 70s or 80s are plagued by degenerative illnesses in the years before their death; in contrast, Perls has found that Read the rest of this entry »

The Robert Wood Johnson Foundation (RWJF) just announced more than $1.85 million in grants for research teams to study how digital games can improve players’ health behaviors and outcomes (both brain-based and behavioral).

The press release: Nine Leading Research Teams Selected to Study How Digital Games Improve Players’ Health

• “Digital games are interactive and experiential, and so they can engage people in powerful ways to enhance learning and health behavior change, especially when they are designed on the basis of well-researched strategies,” said (UC Santa Barbara’s Dr. Debra) Lieberman.
• “The pace of growth and innovation in digital games is incredible, and we see tremendous potential to design them to help people stay healthy or manage chronic conditions like diabetes or Parkinson’s disease. However, we need to know more about what works and what does not — and why,” said Paul Tarini, team director for RWJF’s Pioneer Portfolio. “Health Games Research is a major investment to build a research base for this dynamic young field. Further, the insights and ideas that flow from this work will help us continue to expand our imagination of what is possible in this arena.”

All 9 studies sound interesting, 3 of them are closer to what we track:

1. University of California, San Francisco (San Francisco, CA) A Video Game to Enhance Cognitive Health in Older Adults. As people age, they lose some of their ability to sustain their attention and to focus their attention on their main task while ignoring distractions. This study aims to improve these and other related cognitive skills by using a driving game in which Read the rest of this entry »

Very interesting announcement yesterday, by Lumos Labs and researchers Susanne Jaeggi and Martin Buschkuehl:

“The Lumosity.com version of Dual N-Back replicates the training previously used in the lab while making it available online. The program will be used to facilitate further research in memory and intelligence training, with the Lumosity Research Platform supporting data collection and study administration.”

“The online availability of the dual n-back task is a great step forward for our ongoing research and we are happy having found Lumos Labs as a competent partner,” says Dr. Buschkuehl.

Also note that the researchers are now recruiting healthy 18-35 year-old volunteers to participate in an ongoing study. (Participants must be able to travel to Ann Arbor, Michigan for testing). Learn more Here.

You may also enjoy this interview with Dr. Buschkuehl on their working memory training work.

The Robert Wood Johnson Foundation just announced a new initiative of their Pioneer portfolio:

“On November 11-12, the Robert Wood Johnson Foundation (RWJF), working with the Monitor Institute, will welcome a small group of researchers, academics, physicians and industry leaders in the fields of neurotechnology, neurodevelopment and behavior change for a “Forum on the Future Impact of Neuroscience and Behavior Change.”

The question: what could neuroscience innovation mean for the future of health and health care?

This blog post contains the list of  participants (honored to be one) and an excellent contextual overview. 

Foundation staff will blog and tweet the event (haven’t seen the hashtag yet); I will link to good materials and offer my own perspective focused on that “neurodevelopment” aspect and, overall, where/ how research and the real-world can “dance” with each other.

A few eternal questions:
- Is caffeine good for the brain?
- Does it boost cognitive functions?
- Does it protect against dementia?

There is little doubt that drinking that morning cup of coffee will likely increase alertness, but the main questions that research is trying to answer go beyond that. Basically: is there a sustained, lifetime, benefit or harm from drinking coffee regularly?

The answer, so far, contains good news and bad news. The good news for coffee drinkers is that most of the long-term results are directionally more positive than negative, so no clear harm seems to occur. The bad news is that it is not clear so far whether caffeine has beneficial effects on general brain functions, either short-term or long-term (aged-related decline or risks of dementia).

It is important to note that many of the studies showing an effect of coffee consumption on brain functions or risks of dementia report a correlation or association (they are not randomized clinical trials). As you know, correlation doesn’t prove causation: coffee drinkers may seem to do well in a number in these long-term studies, but there may be other reasons why coffee drinkers do better.

Q: How does caffeine affect my brain?
A: Caffeine is a stimulant.

It belongs to a chemical group called xanthine. Adenosine is a naturally occurring xanthine in the brain that slows down the activity of brain cells (neurons). To a neuron, caffeine looks like adenosine. It is therefore used by some neurons in place of adenosine. The result is that these neurons speed up instead of slowing down.

This increased neuronal activity triggers the release of the adrenaline hormone, which will affect your body Read the rest of this entry »

Encephalon (brain & mind blog carnival, edition ) finally meets Grand Rounds (health & medicine blog carnival).

What a nice surprise. Hello. Nice to meet you!

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Note: Chronic Babe wins a complimentary copy of The SharpBrains Guide to Brain Fitness for basically inventing cognitive sleep therapy. Congrats!

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Life and Death

MindHacks discusses an unexpected surge in brain activity when blood pressure drops to zero.

In Sickness & In Health suffers a death in the family. Adam shem tov. A man of good name.

BrainBlogger wonders, is religion a “natural” phenomenon?

Mind and Empathy

Behaviorism & Mental Health finds that everyone can have a mental illness – take a look at “Adjustment Disorder“.

ACP Internist reinforces the importance of empathy. Novel Patient encourages patients to dream big, Florecendotcom highlights how patients themselves contribute to patient safety. The Hippocratic Oaf discusses the feelings of a medical student. Clinical Cases wonders what doctors  in training carry in their white coats.

Advances in the History of Psychology examines an important early step in the journey to conceptualize cognition and emotion from a neural point of view.

The Fitness Fixer empathizes with her feet.

Brain

How to Cope With Pain discusses a controversial treatment for severe pain.

Neurophilosopher shows how vision (viewing one’s body) can modulate the senses of touch and pain. Fun experiments  included. Neurocritic takes things one step further, and takes us to the potential future of tattoo removal.

Providentia announces a new NFL Concussion Committee. 300,000 sports-related traumatic brain injuries occur in the United States alone each year.

SharpBrains answers 15 common questions related to neuroplasticity.

Medical Smartphones Read the rest of this entry »

We are now finalizing agenda and contacting sponsors and partners. Details will be ready, and registration open, by the end of October. In the meantime, please Save the Date if you are interested in participating: January 18-20th 2010 (Pacific Time).

• Conference: January 18-19th. A series of 30-minute sessions (20-minute presentation, 10-minute Q&A), to discuss Market and Research Insights,  together with online discussions and, in some cities, social gatherings of participants.
• Expo Day: January 20th. Product demos by Sponsors.

Confirmed speakers and themes:

Monday, January 18th, 2010:

Cognition and Neuroplasticity: The New Healthcare Frontier

• Alvaro Fernandez, CEO, SharpBrains
• David Whitehouse, Chief Medical Officer, OptumHealth Behavioral Solutions
• William Reichman, President, Baycrest
• P Murali Doraiswamy, Biological Psychiatry Division Head, Duke University

Tools for Safer Driving: Teenagers and Older Adults

• Steven Aldrich, CEO, Posit Science
• Peter Christianson, President of Young Drivers of Canada
• Jerri Edwards, Assoc. Professor University of South Florida

Clinical Applications: Researching, Identifying, Treating Cognitive Deficits

• Keith Wesnes, Practice Leader, United BioSource Corporation
• Jonas Jendi, CEO, Cogmed
• Michel Noir, President, Scientific Brain Training
• Elkhonon Goldberg, Chief Scientific Advisor, SharpBrains

Read the rest of this entry »

Here you have the October edition of our monthly newsletter covering cognitive health and brain fitness topics. Please remember that you can subscribe to receive this Newsletter by email, using the box at the top of this page.

We recently run an online survey among subscribers of our monthly eNewsletter, and over 500 people said we have helped them make better personal or professional decisions on how to maintain and improve brain fitness. Most gave very illuminating examples, which we are reading and enjoying as we speak.

Respondents also had many good questions to ask, so I have selected 15 common ones, paraphrased/ synthesized them below, and answered them by linking to our most relevant posts and resources. I hope you enjoy the FAQ session.

Q: I teach a brain fitness class at my library/ senior center/ school, using much of your info. Can you share some of your presentations?
A: Yes, we have just decided to share, using a Creative Commons Attribution No Derivatives License, the full presentation of my recent book talk at New York Public Library. As long as you give credit to SharpBrains and don’t modify it, you are free to use the presentation you can see and download HERE. The talk was videotaped, and will be available online soon, so please keep tuned.

Q: What exactly does neuroplasticity mean, and why is it so important for education and health?
A: Start by reading how learning changes your brain.

Q. Is this only relevant for older adults? Can I also apply it in the workplace (I am 47)
A. I strongly suspect you do have a human brain, so you may benefit from these Ten Habits of Highly Effective Brains. Further, HR departments would do well to start paying more attention to Cognitive Fitness and the Mature Workforce trends.

Q. I read so many conflicting things I don’t know where to start.
A. You are not alone. We should all be aware that It is Not Only Cars That Deserve Good Maintenance: Brain Care 101.

Q. How can my organization deliver brain fitness activities as a community service?
A. These articles will provide good guidelines and ideas: Retooling Use It or Lose It , and Public Libraries: Community-Based Health Clubs for the Brain.

Q. Everyone seems obsessed with brain games. What about meditation?
A. Check out Yes, You Can Build Willpower, and Mindfulness Meditation in Schools.

Q. Are software-based cognitive interventions effective?
A. As a category, it certainly seems so, as long as we ask the right questions, For Whom, For What?. For example, did you see this Science paper on how Cognitive Training Can Influence Dopamine System?.

Q. What about the trade-off between time invested vs benefits realized.
A. Efficiency and replicability of cognitive and brain-based outcomes seem to be, in fact, the strongest points of structured cognitive interventions. They seem to maximize the Cognitive Value of your Mental Workout.

Q. It sometimes looks like the whole field came out of nowhere, due to Nintendo Brain Age’s success, so we can’t be talking about something serious.
A: Nintendo did indeed create consumer awareness (for a product with little evidence) but “brain training” has solid roots in neuropsychology and cognitive neuroscience, as you can read in our interview with Elkhonon Goldberg.

Q. What about neurofeedback?
A. After years of much clinical use and little solid evidence, several important trials have been published in 2009, showing how neurofeedback can help diagnose and treat ADHD patients.

Q. How can one improve memory?
A. Well, the answer deserves a whole book, but we can offer some Tips to Improve Memory including Sleep, Practice and Testing.

Q. How can I choose one among the number of products making memory and brain claims?
A. We suggest you use this Evaluation checklist, and consider reading our consumer guide/ book.

Q. Any general tips for educators and lifelong learners?
A. Indeed, here you have these 10 Brain Tips to Teach and Learn.

Q. How can I keep track of all the new trends, companies and products? Our health system/ insurer/ senior community/ venture firm/ company needs to make good decisions.
A. Well, that’s why we publish market research, such as the one summarized in this Infographic: State of the Market 2009 and also recently launched a professional Network for Brain Fitness Innovation. You can also Save the Date for the upcoming SharpBrains Summit.

Q: Thank you for all the information you provide…but what I want more of is… brain teasers!
A. Understood. We will make sure to offer more, but you can try, right now, these Top 50 Brain Teasers and continue with more recent puzzles and brain games.

I will be hosting Grand Rounds, the weekly collection of great health and medical blogging, on Tuesday, October 20th. Please send me your post at alvaro (at) sharpbrains (dot) com, indicating Grand Rounds in the title. Please do so before end of Sunday, October 18th, USA time.

Optional theme will be, of course: Cognition and the Brain. Would you share your thoughts and experiences on how cognitive neuroscience and neuropsychology should, will, or may, be used to improve health and healthcare? what opportunities you see for preventive and/ or clinical care to better deal with the assessment, maintenance, rehab, of cognitive and emotional functions, across the lifespan?

Reward for the extra brain exercise? I will give away a complimentary copy of The SharpBrains Guide to Brain Fitness, our recent book, to the blogger who (in my editorial judgement) offers the most insightful post.

The theme is optional. Grand Rounds will include all other important topics you write about. Looking forward a stimulating edition!

Excellent article in the New York Times on learning, self-regulation and executive fuunctions:

The School Issue: Preschool: Can the Right Kinds of Play Teach Self-Control? (New York Times)

- “Over the last few years, a new buzz phrase has emerged among scholars and scientists who study early-childhood development, a phrase that sounds more as if it belongs in the boardroom than the classroom: executive function. Originally a neuroscience term, it refers to the ability to think straight: to order your thoughts, to process information in a coherent way, to hold relevant details in your short-term memory, to avoid distractions and mental traps and focus on the task in front of you. And recently, cognitive psychologists have come to believe that executive function, and specifically the skill of self-regulation, might hold the answers to some of the most vexing questions in education today.”

- “The ability of young children to control their emotional and cognitive impulses, it turns out, is a remarkably strong indicator of both short-term and long-term success, academic and otherwise.”

A truly excellent article, highly recommended reading. The only aspect lacking is the absence of coverage/ analysis of training-based alternatives to developing self-regulation, such as meditation and computerized cognitive training, which can help address some of the issues raised in the article (limited scalability, difficulty in isolating influential variables). We covered this in-depth in our book interview with Michael Posner.