Feb 26th, 2008
Brain Plasticity: How learning changes your brain
Do you want to change your brain? (for the better, we all hope!). Keep reading Dr. Pascale Michelon's blog post...
---------------
You may have heard that the brain is plastic. As you know the brain is not made of plastic! Neuroplasticity or brain plasticity refers to the brain’s ability to CHANGE throughout life. The brain has the amazing ability to reorganize itself by forming new connections between brain cells (neurons).
In addition to genetic factors, the environment in which a person lives, as well as the actions of that person, play a role in plasticity.
Neuroplasticity occurs in the brain:
1- At the beginning of life: when the immature brain organizes itself.
2- In case of brain injury: to compensate for lost functions or maximize remaining functions.
3- Through adulthood: whenever something new is learned and memorized
Plasticity and brain injury
A surprising consequence of neuroplasticity is that the brain activity associated with a given function can move to a different location as a consequence of normal experience, brain damage or recovery.
In his book “The Brain That Changes Itself: Stories of Personal Triumph from the Frontiers of Brain Science”, Norman Doidge describes numerous examples of functional shifts.
In one of them, a surgeon in his 50s suffers a stroke. His left arm is paralyzed. During his rehabilitation, his good arm and hand are immobilized, and he is set to cleaning tables. The task is at first impossible. Then slowly the bad arm remembers how too move. He learns to write again, to play tennis again: the functions of the brain areas killed in the stroke have transferred themselves to healthy regions!
The brain compensates for damage by reorganizing and forming new connections between intact neurons. In order to reconnect, the neurons need to be stimulated through activity.
Plasticity, learning and memory
For a long time, it was believed that as we aged, the connections in the brain became fixed. Research has shown that in fact the brain never stops changing through learning. Plasticity IS the capacity of the brain to change with learning. Changes associated with learning occur mostly at the level of the connections between neurons. New connections can form and the internal structure of the existing synapses can change.
Did you know that when you become an expert in a specific domain, the areas in your brain that deal with this type of skill will grow?
For instance, London taxi drivers have a larger hippocampus (in the posterior region) than London bus drivers (Maguire, Woollett, & Spiers, 2006)…. Why is that? It is because this region of the hippocampus is specialized in acquiring and using complex spatial information in order to navigate efficiently. Taxi drivers have to navigate around London whereas bus drivers follow a limited set of routes.
Plasticity can also be observed in the brains of bilinguals (Mechelli et al., 2004). It looks like learning a second language is possible through functional changes in the brain: the left inferior parietal cortex is larger in bilingual brains than in monolingual brains.
Plastic changes also occur in musicians brains compared to non-musicians. Gaser and Schlaug (2003) compared professional musicians (who practice at least 1hour per day) to amateur musicians and non-musicians. They found that gray matter (cortex) volume was highest in professional musicians, intermediate in amateur musicians, and lowest in non-musicians in several brain areas involved in playing music: motor regions, anterior superior parietal areas and inferior temporal areas.
Finally, Draganski and colleagues (2006) recently showed that extensive learning of abstract information can also trigger some plastic changes in the brain. They imaged the brains of German medical students 3 months before their medical exam and right after the exam and compared them to brains of students who were not studying for exam at this time. Medical students’ brains showed learning-induced changes in regions of the parietal cortex as well as in the posterior hippocampus. These regions of the brains are known to be involved in memory retrieval and learning.
Plasticity and brain exercises
You know that exercising or stimulating your brain is highly recommended as part of a brain-healthy lifestyle. You may have wondered why? What is the reasoning behind the “use it or lose it” idea? Brain exercises have an impact on brain health thanks to the brain’s plasticity. When you exercise or stimulate your brain through new or merely unfamiliar activities, you can trigger changes in the brain, such as an increase of connections between neurons. These changes contribute to an increase in what is called your brain reserve. Research suggests that the more brain reserve, the more resistant the brain is to age-related or disease-related damages.
--- This article was written by Pascale Michelon, Ph. D., for SharpBrains.com. Dr. Michelon has a Ph.D. in Cognitive Psychology and has worked as a Research Scientist at Washington University in Saint Louis, in the Psychology Department. She conducted several research projects to understand how the brain makes use of visual information and memorizes facts. She is now an Adjunct Faculty at Washington University, and teaches Memory Workshops in numerous retirement communities in the St Louis area.
---------------
If you are interested in learning more:
- Recommended Books on Brain and Mind
- Build Your Cognitive Reserve, an Interview with Yaakov Stern
- The Art of Changing the Brain, an Interview with James Zull



Really interesting. Neuroplasticity also plays a huge role in the development and maintenance of chronic pain.
It appears that chronic pain is a learned neurological response. It would be wonderful if someone could develop and effective way of unlearning this response.
Hello Mark, we are less familiar with pain research but I'd suspect what you say is right.
In general, the best way to "unlearn" a response is by learning a new response that overtakes the previous one.
If you come across interesting research in that field, please let us know!
Just curious,
How does the "learning" of how to use your second hand fit into this? i.e a right hander becoming ambidexturous?
Are the same processes involved in terms of rewiring between hemispheres of the brain? Is it possible to develop handedness by focusing on the skill or this something more gene related?
Thanks,
Amol
Hi Amol,
I would think that learning to use your non-dominant hand does involve plasticity. My guess is that the area in the motor cortex that corresponds to that hand will start developing as a result of the increased movement in that hand.
It is precisely because the brain has neural plasticity that EEG neurofeedback works.
Amol, the brain can retrain itself (strengthening the new neuronal pathways, when given direction via a biofeedback system operating on EEG measurements.
It takes time for the new pathways to become dominant/habitual, but once they do, the results of EEG neurofeedback are largely permanent.
Similarly, (but on the opposite end of the spectrum), epilepsy patients that do not get their seizure activity under control (only something like 40% gain 100% control through drug therapy) are at risk of a process called kindling - where the brain learns/trains itself to seize. The wrong neuronal pathways are being strengthened in that case.
I recommend having a look at Stephen Larson's book, The Healing Power of Neurofeedback: The Revolutionary LENS Technique for Restoring Optimal Brain Function. It references several interesting studies on the subject.
Bernard: neuroplasticity explains why any kind of learning can occur. It is a premise for all learning. And a variety of training programs, such as neurofeedback, can be helpful in guiding neuroplasticity in appropriate ways.
Now, the question is: what is the causal, direct, evidence that a given training intervention is producing the right kind of learning? Neuroplasticity itself does not address that.
[...] Alvaro Fernandez presents Brain Plasticity: How learning changes your brain posted at SharpBrains, saying, "Why do London taxi drivers have some larger brain structures than London bus drivers and why does this matter? See what Dr. Pascale Michelon has to say." [...]
I have a friend who is barely 40 & had 2 strokes (clots). It has been 5 years. Her left side is paralyzed. Then I saw a PBS show on neuroplasticity. Is there some kind of PT or other program I can do with her to help her brain re-learn? She is a good, kind, loving person & doesn't deserve to live like this.
Hello Debbie,
Your friend's neuropsychologist would be the ideal person to suggest what specific physical and mental activities ca help the rehabilitation process. No two strokes affect the same areas.
I hope she gets better. You may enjoy the superb book by the Woodruffs,
In an Instant: A Family's Journey of Love and Healing (Hardcover)