The Hous­ton Chron­i­cle ran an inter­est­ing story the other day that addresses a num­ber of com­mon per­cep­tions about menopause. The one that caught our atten­tion is:

The hor­monal changes of menopause turn your brain to mush.
Unproven. There is some evi­dence that women with low estro­gen lev­els expe­ri­ence faster cog­ni­tive decline, and women who take estro­gen sup­ple­ments some­times do bet­ter on cer­tain mem­ory tests. But the evi­dence is incon­sis­tent. Accord­ing to the Women’s Health Ini­tia­tive, women older than 65 who took Prem­pro had a higher risk of get­ting Alzheimer’s dis­ease and other forms of demen­tia than women tak­ing dummy pills. Other stud­ies, how­ever, have sug­gested that estro­gen use pro­tects against Alzheimer’s if it’s started near the onset of menopause. Some experts now believe estro­gen can pro­tect both the brain and the heart if it’s started early, before age-related dete­ri­o­ra­tion sets in, but not after that win­dow of oppor­tu­nity closes.

A lon­gi­tu­di­nal study pub­lished in 2003 also con­cluded menopause does not cause cog­ni­tive decline. Sci­ence Blog quotes:

“The study is impor­tant because it shows that there is lit­tle or no risk for imme­di­ate mem­ory loss dur­ing per­i­menopause,” said Sam Gandy, M.D., Ph.D., vice chair of the Alzheimer’s Association’s Med­ical and Sci­en­tific Advi­sory Coun­cil, and direc­tor, Far­ber Insti­tute for the Neu­ro­sciences of Thomas Jef­fer­son University.

On the other hand, an Octo­ber 2006 pub­li­ca­tion, found that longer treat­ment with estro­gen hor­mone replace­ment ther­apy (HRT) in post­menopausal women pro­tected neu­rons in the hip­pocam­pus against age-related cog­ni­tive decline. Another recent pub­li­ca­tion in Menopause con­cludes that tim­ing is everything.

Pro­fes­sor Alas­tair MacLen­nan said, “This study has shown us that using HRT early in menopause, or even just before the final men­strual period, resulted in bet­ter cog­ni­tive per­for­mance later in life than in women of sim­i­lar age and back­ground who had never used HRT.

”How­ever, start­ing HRT many years after menopause was not asso­ci­ated with any cog­ni­tive benefit.“

A great post by iqte.st based on an arti­cle from the APA points out:

While nobody thinks women should take hor­mones to improve their brain health, doc­tors say women who choose hor­mones to relieve hot flashes should be reas­sured by recent news that hor­mones may help boost think­ing skills. And Dr. Joffe notes that every­one, whether it’s a woman dur­ing menopause or a man jug­gling mul­ti­ple respon­si­bil­i­ties, can take active steps to improve their daily cog­ni­tive func­tion. The main rea­son peo­ple feel like their mem­ory or think­ing skills are slip­ping is usu­ally due to lack of atten­tion, she says. If some­thing is impor­tant, take the time to repeat it, write it down and make sure the infor­ma­tion is reg­is­ter­ing in your brain.

What can you do to stay men­tally sharp?
The good news is whether or not you and your doc­tor decide to go with hor­mone replace­ment ther­apy, lifestyle choices like exer­cise, nutri­tional man­age­ment, and brain exer­cise can help alle­vi­ate the symp­toms of menopause and aging. If you feel men­tally fuzzy, try var­i­ous strate­gies for deal­ing with weak atten­tion or try some of the brain fit­ness pro­grams out there that specif­i­cally work on increas­ing atten­tion and memory.

Related Links
50 Ways to Cope With Menopause by Dr. Linda Hughey Holt and Ada P. Kahn
North Amer­i­can Menopause Soci­ety
Inter­view with Dr. Torkel Kling­berg, researcher in work­ing mem­ory
–Caroline

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