A new study tries to, but unfor­tu­nately doesn’t, answer that ques­tion. Study: Brain Train­ing Game Improves Exec­u­tive Func­tions and Pro­cess­ing Speed in the Elderly: A Ran­dom­ized Con­trolled Trial (PLoS ONE).

“Con­clu­sions: Our results showed that play­ing Brain Age for 4 weeks could lead to improve cog­ni­tive func­tions (exec­u­tive func­tions and pro­cess­ing speed) in the elderly. This result indi­cated that there is a pos­si­bil­ity which the elderly could improve exec­u­tive func­tions and pro­cess­ing speed in short term train­ing. The results need repli­ca­tion in large sam­ples. Long-term effects and rel­e­vance for every-day func­tion­ing remain uncer­tain as yet.” Read the rest of this entry »

We just came across a new sci­en­tific study on the value and lim­i­ta­tions of cog­ni­tive train­ing in Mild Cog­ni­tive Impair­ment (MCI), based on a pro­gram of cog­ni­tive exer­cises pro­vided by Lumos Labs (devel­op­ers of lumosity.com).

Study: Com­put­erised Cog­ni­tive Train­ing for Older Per­sons With Mild Cog­ni­tive Impair­ment: A Pilot Study Using a Ran­domised Con­trolled Trial Design (Brain Impair­ment): Read the rest of this entry »

Every Mon­day dur­ing the next 10 weeks we’ll dis­cuss here what lead­ing indus­try, sci­ence and pol­icy experts –all of whom will speak at the upcom­ing 2011 Sharp­Brains Sum­mit (March 30th — April 1st, 2011)– have to say about emerg­ing oppor­tu­ni­ties and chal­lenges to address, over the next 10 years, the grow­ing brain-related soci­etal demands.

With­out fur­ther ado, here you have what four Sum­mit Speak­ers say…

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Alvaro Pascual-Leone is the Direc­tor of the Berenson-Allen Cen­ter for Non-Invasive Brain Stim­u­la­tion at Har­vard Med­ical School.

1. How would you define “brain fit­ness” vs. “phys­i­cal fit­ness”?

Phys­i­cal fit­ness can refer to an over­all or gen­eral state of health and well-being. How­ever, it is also often used more specif­i­cally to refer to the abil­ity to per­form a given activ­ity, occu­pa­tion, or sport.

Sim­i­larly brain fit­ness might be used to refer to a gen­eral state of healthy, opti­mized brain func­tion, or a more spe­cific brain-based abil­ity to process cer­tain, spe­cific infor­ma­tion, enable cer­tain motor actions, or sup­port cer­tain cog­ni­tive abil­i­ties. Impor­tantly though, I would argue Read the rest of this entry »

We offered some Brain Fit­ness Pre­dic­tions in our Mar­ket Report , including…

“7. Doc­tors and phar­ma­cists will help patients nav­i­gate through the over­whelm­ing range of avail­able prod­ucts and inter­pret the results of cog­ni­tive assess­ments. This will require sig­nif­i­cant pro­fes­sional devel­op­ment efforts, given that most doc­tors today were trained under a very dif­fer­ent under­stand­ing of the brain than the one we have today.”

The Amer­i­can Med­ical News, a weekly news­pa­per for physi­cians pub­lished by the Amer­i­can Med­ical Asso­ci­a­tion, just pub­lished an excel­lent arti­cle along those lines:

Steps to a nim­ble mind: Phys­i­cal and men­tal exer­cise help keep the brain fit
– Neu­ro­science is uncov­er­ing tech­niques to pre­vent cog­ni­tive decline.

A few quotes:

- It’s an exam­ple that high­lights a wave of new think­ing about the impor­tance of brain fitness.

- Until recently, con­ven­tional wis­dom held that our brains were intractable, hard-wired com­put­ers. What we were born with was all we got. Age wore down mem­ory and the abil­ity to under­stand, and few inter­ven­tions could reverse this process. But increas­ingly, evi­dence sug­gests that phys­i­cal and men­tal exer­cise can alter spe­cific brain regions, mak­ing rad­i­cal improve­ments in cog­ni­tive function.

- With nearly 72 mil­lion Amer­i­cans turn­ing 65 over the next two decades, physi­cians need the tools to han­dle grow­ing patient con­cerns about how to best main­tain brain health. Armed with this new brand of sci­ence, front­line physi­cians will be bet­ter equipped to address the needs of aging baby boomers, already in the throes of the brain fit­ness revolution.

- “Encour­age them to exer­cise the brain in novel and com­plex ways,” he says.

Full arti­cle: here

One of the physi­cians quoted in the arti­cle is Gary J. Kennedy, MD, Direc­tor of the Divi­sion of Geri­atric Psy­chi­a­try at Mon­te­fiore Med­ical Cen­ter in NYC and a pro­fes­sor in the Dept. of Psy­chi­a­try and Behav­ioral Sci­ences at Albert Ein­stein Col­lege of Medicine.

To put the AMA arti­cle in bet­ter per­spec­tive for Sharp­Brains read­ers, we asked Dr. Kennedy a few follow-up ques­tions. Below you have his questions.

Alvaro Fer­nan­dez (AF): Can you sum­ma­rize how cog­ni­tive func­tions tend to evolve as we age?

Gary Kennedy (GK): As we age cog­ni­tive func­tions that rely on Read the rest of this entry »

As men­tioned before, the World Eco­nomic Forum asked me to write “an 800 words sum­mary of your most com­pelling action­able idea on the chal­lenges of geron­tol­ogy”, in prepa­ra­tion for the Inau­gural Sum­mit of the Global Agenda that will take place Novem­ber 7 to 9th in Dubai.A good num­ber of Sharp­Brains read­ers and clients offered their insights — and expressed an inter­est in read­ing the draft. So below you have — a pro­posal to cre­ate a Global Con­sor­tium for Neu­rocog­ni­tive Fit­ness Inno­va­tion, build­ing on our exist­ing mar­ket research and advi­sory ser­vices work. Your thoughts?

—–

The Con­text

Grow­ing Demands on Our Brains: Pic­ture 6.7 bil­lion Prim­i­tive Brains inhab­it­ing a Knowl­edge Soci­ety where life­long learn­ing and mas­ter­ing con­stant change in com­plex envi­ron­ments are crit­i­cal for pro­duc­tive work, health and per­sonal fulfillment.

Wel­come to Planet Earth, 2008.

Fur­ther stretched by increased longevity: Now pic­ture close to 1 bil­lion of those brains over the age of 60 – and please remem­ber that, less than 100 years ago, life expectancy was between 30 to 40 years. The rapidly evolv­ing Knowl­edge Soci­ety is plac­ing new and enor­mous demands on our “prim­i­tive” human brains. And the longer our lifes­pans, the more obvi­ous the “cog­ni­tive gap”. Hence, from a health point of view, the grow­ing Read the rest of this entry »

Just saw a very inter­est­ing press release regard­ing computer-based neu­rocog­ni­tive assess­ments — a crit­i­cal part of the brain fit­ness puz­zle. How long will it take before con­sumers can have access to a reli­able and cred­i­ble annual “men­tal check-up”/ cog­ni­tive baseline?

Head­Min­der Cog­ni­tive Sta­bil­ity Index: Com­put­er­ized Neu­rocog­ni­tive … (Press release)

- “The Head­Min­der web-based Cog­ni­tive Sta­bil­ity Index (CSI) has proven more use­ful for blast-concussion detec­tion than the ANAM com­put­er­ized test bat­tery the DoD cur­rently employs. The CSI pro­vides an imme­di­ate solu­tion to clear the back­log of 400,000 IED-exposed ser­vice mem­bers in less than two years.”

- “The CSI is a 30-minute, Internet-based, com­put­er­ized test that pro­vides auto­mated, objec­tive mea­sures of atten­tion, mem­ory, response speed, and pro­cess­ing speed for ini­tial eval­u­a­tion of cog­ni­tive func­tion­ing. The CSI pro­duces stan­dard­ized reports that enable triage and decision-making appro­pri­ate to a user’s qual­i­fi­ca­tions — from medic to neu­ropsy­chol­o­gist to neu­rol­o­gist and other treat­ment team members.”

We cov­ered this emerg­ing type of assess­ments in the arti­cle Com­put­er­ized Cog­ni­tive Assess­ments: oppor­tu­ni­ties and concerns

- “In fact, one of the Read the rest of this entry »

Cog­ni­tive train­ing (the basis for what we call “brain fit­ness” these days) has a wide array of appli­ca­tions. The most recent one, which is cap­tur­ing public’s imag­i­na­tion, monop­o­liz­ing media cov­er­age, and cre­at­ing cer­tain con­fu­sion, is Healthy Brain Aging. We are for­tu­nate to have Dr. Joshua Stein­er­man, one of our new Expert Con­trib­u­tors, offer today his great voice to this con­ver­sa­tion. Enjoy!

- Alvaro
—————————

Mind­ing the Aging Brain

– By Joshua R. Stein­er­man, M.D.

Sci­en­tists, philoso­phers, artists, and experts from all fields of human endeavor lament: it ain’t easy get­ting older. It? Do they refer to frailty and dis­abil­ity? To bod­ily dis­ease? To life at its essence?

It’s all in your head

The mind is not set in stone, but it is encased by bone. It’s really all about the brain, the hyphen in the mind-body conun­drum. That squishy gray neu­ronal jun­gle is the inter­face between inter­nal life and envi­ron­men­tal sen­sa­tions and stim­u­la­tion. As expected, the brain shows signs of aging just as a wrin­kled brow, a stooped pos­ture, or an arthritic fin­ger might. The most com­mon brain changes observed in aging and in age-associated neu­ropsy­chi­atric dis­ease include:

Read the rest of this entry »

The hol­i­days are approach­ing and you can expect many soft­ware and game devel­op­ers to adver­tise their prod­ucts aggres­sively, try­ing to get you buy their “brain train­ing” prod­ucts for you or as a gift for a loved one.

The good news is that there are more and more tools we can use to keep men­tally stim­u­lated and even train and improve spe­cific cog­ni­tive abil­i­ties (like pro­cess­ing speed, short-term mem­ory…). You may be read­ing about Nin­tendo Brain Age, Posit Sci­ence, Fast For­Word, Mind­Fit, Lumos­ity, Happy Neu­ron, MyBrain­Trainer, emWave, StressEraser and more. And, of course, there are also non-technology based interventions.

The bad news is that it is dif­fi­cult to sep­a­rate mar­ket­ing from sci­en­tific claims, and to under­stand which one, if any, may be a good com­ple­ment to other healthy lifestyle choices.

To help you nav­i­gate this process, we are pub­lish­ing the Sharp­Brains Check­list below, based on dozens of inter­views with sci­en­tists, experts and consumers:

10 Ques­tions to Choose the Right Brain Fit­ness Pro­gram for You (and a brief expla­na­tion of why each ques­tion is important)

* 1. Are there sci­en­tists, ide­ally neu­ropsy­chol­o­gists, and a sci­en­tific advi­sory board Read the rest of this entry »

Very inter­est­ing col­lec­tion of recent news…let’s con­nect some dots

1) Great arti­cle titled Boom time for retirees (Finan­cial Times)

- “By 2015, boomers will have a net worth of some $26,000bn (£12,750bn, ¬17,670bn)  equiv­a­lent to a year’s gross domes­tic prod­uct for the US and euro­zone com­bined. They will con­trol a larger pro­por­tion of wealth, income and con­sump­tion than any other gen­er­a­tion in the coun­try  the first time that con­sumers over 50 have held such sway over the world’s largest economy.”

- “But as the boomers aged by 2015 they will all be out­side the fabled under-49 cohort  cor­po­rate Amer­ica failed to grow old with them. Mar­ket­ing experts argue that the con­tin­ued focus of large com­pa­nies such as P&G and Gap on the youth of  “gen­er­a­tion and “gen­er­a­tion” over­looks a sim­ple sta­tis­tic: the 18–49 age group will grow by only 1m peo­ple in the next 10 years, com­pared with the 22.5m Amer­i­cans set to enter the 50-plus bracket.”

- “The last thing the [boomer] gen­er­a­tion needs is a com­pany that tells them they need tools to address their lack of dex­ter­ity, he says. “They don’t want geri­atric tools, they want cool stuff.

Main take-way: baby boomers are always “awake” and rein­vent­ing things…companies, adver­tis­ers, time to wake-up!

Full arti­cle: Boom time for retirees

2) The arti­cle is based upon this excel­lent McK­in­sey report Read the rest of this entry »

A cou­ple of quick links

• DISCOVER Mag­a­zine, May 2007 issue, brings a great arti­cle titled “The Elas­tic Brain: Michael Merzenich believes you can tone your mind and stave off mem­ory loss. All it takes is time in his men­tal gym”. The arti­cle (which is not avail­able online) pro­vides a great overview of the amaz­ing work of Prof. Merzenich (a UCSF neu­ro­sci­en­tist) with Sci­en­tific Learn­ing and Posit Sci­ence, pio­neers in the field. The writer’s tone is pos­i­tive over­all but adds a note of skep­ti­cism, say­ing that “Yet despite the enthu­si­as­tic tes­ti­mony I heard from senior cit­i­zens who have tried the pro­gram, there are no for­mal stud­ies pub­lished in peer-reviewed jour­nals that demon­strate the program’s effects” and gath­er­ing crit­i­cisms out­lined by other researchers. Hav­ing said so, in our opin­ion, Posit Sci­ence offers the best pro­gram we have seen focused on improv­ing audi­tory pro­cess­ing, and we expect to see more clear stud­ies soon-the field is rel­a­tively new.
• Slate Mag­a­zine presents a spe­cial issue on the brain. We will review and com­ment on it soon, includ­ing a neu­ro­bic club/ brain gym.

You can see here an inter­view with inter­view with Dr. Michael Merzenich