Sharp Brains: Brain Fitness and Cognitive Health News

Neuroplasticity, Brain Fitness and Cognitive Health News

Scientific critique of BBC/ Nature Brain Training Experiment

logo-bbcThere has been quite a bit of com­ment about the Owen et al study in Nature avail­able online on April 20, 2010. A quick syn­op­sis of the study is that the BBC show Bang Goes the The­ory worked with the study authors to pro­vide a test of the hypoth­e­sis that com­mer­cially avail­able brain train­ing pro­grams trans­fer to gen­eral cog­ni­tive abil­i­ties. The con­clu­sion was that, despite improve­ments on the trained tasks, “no evi­dence was found for trans­fer effects to untrained tasks, even when those tasks were cog­ni­tively closely related.”

The exper­i­ment

The study was con­ducted through the show’s web site. Of 52,617 par­tic­i­pants who reg­is­tered, approx­i­mately 20% (11,430) com­pleted full par­tic­i­pa­tion in the study, which con­sisted of two bench­mark­ing assess­ments 6 weeks apart with vari­ants of neu­ropsy­cho­log­i­cal tests and at least two train­ing ses­sions. Peo­ple were ran­domly assigned to one of three groups that were asked to train for about 10 min a day three times a week for the 6-week period, though they could train either more or less fre­quently. One of the two exper­i­men­tal groups was a “brain train­ing” group that com­pleted tasks includ­ing sim­ple arith­metic, find­ing miss­ing pieces, match­ing sym­bols to a tar­get, order­ing rotat­ing num­bers by numer­i­cal value, updat­ing, and mem­ory for items. Most of the train­ing ses­sions were 90 sec each; the rotat­ing num­bers tasks was 3 min. These activ­i­ties are sim­i­lar to those used in “edu­tain­ment” pro­grams that can be played online or with a hand­held device. The other exper­i­men­tal group was trained on rea­son­ing tasks that involved iden­ti­fy­ing rel­a­tive weights of objects based on a visual “see­saw”, select­ing the “odd” item in a con­cept for­ma­tion type task, a task involv­ing think­ing through the effects of one action on cur­rent and future states, and three plan­ning tasks includ­ing draw­ing a con­tin­u­ous line around a grid while ascer­tain­ing that the line will not hin­der later moves, a ver­sion of the Tower of Hanoi task, and a tile slid­ing game. The con­trol group spent time answer­ing ques­tions about obscure facts and orga­niz­ing them chrono­log­i­cally based on any avail­able online resource. Results indi­cated that the two exper­i­men­tal groups per­formed bet­ter than the con­trol group on only one out­come test of gram­mat­i­cal rea­son­ing; there were no dif­fer­ences between either exper­i­men­tal group and the con­trols on the remain­ing test. The exper­i­men­tal groups had improved on the trained tasks but not on the trans­fer tasks.

Sci­en­tific concerns

Although some news reports sug­gest that these find­ings are defin­i­tive, there are a num­ber of con­cerns, many of which have to do with whether the find­ings have been over­gen­er­al­ized to all forms of brain train­ing because only a few tests were used. Sec­ond, there have been ques­tions raised about the amount of time allo­cated to train­ing and the issue of test­ing in the home envi­ron­ment. The study reported Read the rest of this entry »

PABI Plan: Reinventing Brain Care Through Policy, Standards, Tech, Neuroinformatics

Today, in honor of both Brain Aware­ness Week (March 15–21) and Brain Injury Aware­ness Month (March), it is my plea­sure to inter­view Patrick Dono­hue, founder of the Sarah Jane Brain Project, a foun­da­tion launched in 2007 with the explicit aim to cre­ate a model sys­tem for chil­dren suf­fer­ing from all Pedi­atric Acquired Brain Injuries, and an implicit poten­tial, in my view, to fun­da­men­tally trans­form med­ical research through the use of neu­roin­for­mat­ics and stan­darized sys­tems of care.

The Foun­da­tion: Story and Objectives

Alvaro Fer­nan­dez: Patrick, thank you very much for your time today. Can you please pro­vide an over­all per­spec­tive into what you are doing and why?

Patrick: Of course. The Sarah Jane Brain Project, tdy_robach_shakenbaby_081114.300w named after my daugh­ter Sarah Jane, started when she was shaken by her baby nurse when she was 5 days of age, which resulted in a severe brain injury. Through my con­tin­ued efforts to help her, I couldn’t help but notice that the whole field of brain injury needs to make huge progress in a short time frame if it is to really help Sarah Jane — and thou­sands of chil­dren like her — with pro­vid­ing evidence-based, stan­dard­ized sys­tems of care. Prob­a­bly 85% of patient needs are com­mon, yet each case seems to require rein­vent­ing the wheel. Worse, lit­tle research has been done on children’s rehabilitation.

We prob­a­bly know about 5% of what we will even­tu­ally know about the brain. The sys­tems of research and care remind me of the com­puter sci­ence field in the 1950s: very promis­ing, but frac­tured and incon­sis­tent. In con­sult­ing with many experts on ways to accel­er­ate progress, we real­ized we need to bring both sig­nif­i­cantly more resources and open source prin­ci­ples to the field of pedi­atric neu­rol­ogy. We launched the Sarah Jane Brain Project to trans­form the field to help Sarah Jane and thou­sands of kids like her.

Before you launched the Foun­da­tion, you worked as a lawyer and polit­i­cal con­sul­tant. How did that back­ground help, or hin­der, those very ambi­tious goals?

I believe my back­ground was a great help, to bring an out­side per­spec­tive to the prob­lems that many sci­en­tists and doc­tors were already work­ing on, and to know how to work with politi­cians and policy-makers to obtain needed atten­tion and resources.

Pedi­atric Trau­matic Brain Injury (PTBI) is the lead­ing cause of death and dis­abil­ity for chil­dren and young adults from birth through 25 years of age in the United States, with more new cases in any given year than HIV/AIDS and Autism com­bined, yet it only receives a paultry por­tion of fed­eral research money (we are talk­ing a few mil­lion for brain injury vs, lit­er­ally, bil­lions toward other dis­ease states that have less cases), and it was basi­cally ignored dur­ing the ongo­ing health reform process.

Talk­ing to dozens of experts, I met mul­ti­ple net­works and indi­vid­u­als in the TBI care com­mu­nity who had already iden­ti­fied the need to develop a solid pedi­atric model sys­tem, but needed sup­port and resources. We brain­stormed poten­tial strate­gies, and came to see that we would need to cover all Acquired Brain Injury (includ­ing both trau­matic and not trau­matic causes), to increase learn­ing, and to truly be, as I often say, “on the side of the angels” (I have wit­nessed before how move­ments fail when they start to become myopic and arbi­trary). We also decided to cover birth to 25 years of age, given the slow mat­u­ra­tion of the frontal lobes. We wanted to develop best plan pos­si­ble, irre­spec­tive of sta­tus quo con­sid­er­a­tions. For exam­ple, we con­sciously decided not to tai­lor our plan to the idio­syn­cratic pref­er­ences of dif­fer­ent fund­ing sources, but to present the National PABI Plan, a large, and unso­licited, multi-department grant that crossed 7 departments.

Polit­i­cal ears respond to vic­tims’ sto­ries, and to budget-neutral plans. Our con­cur­rent res­o­lu­tion of Con­gress (H.Con.Res.198) has over 100 co-sponsors in the U.S. House. This mea­sure has the United States Con­gress endors­ing this National PABI Plan as the plan to pre­vent, iden­tify and treat all brain injuries from birth through 25 years of age while encour­ag­ing fed­eral, state and local gov­ern­ments to begin imple­ment­ing it. We expect it to pass very soon.

Pol­icy Inno­va­tion at Fed­eral and State Lev­els

Please explain the ori­gins and core ele­ments of the PABI Plan (opens 500+ PDF document)

Our National Advi­sory imagesBoard gath­ered in New York City for a three-day con­fer­ence on Jan­u­ary 8–10, 2009, to fin­ish draft­ing the PABI Plan. On Jan­u­ary 20, 2009, we sent the first let­ter to Pres­i­dent Barack Obama at 12:01 p.m. intro­duc­ing the PABI Plan to him.

At its core, the PABI plan wants to fund and imple­ment a new model sys­tem, using open source infor­mat­ics for the first time in med­ical his­tory, to assist in the study and reha­bil­i­ta­tion of chil­dren suf­fer­ing from Pedi­atric Acquired Brain Injury (PABI). Fam­i­lies will be able to make avail­able, on an anony­mous basis, the com­plete med­ical and ther­apy records and infor­ma­tion of chil­dren suf­fer­ing from PABI to doc­tors, researchers, other par­ents and care­givers, ther­a­pists, stu­dents and the gen­eral public.

Our part­ners in this are 52 State Lead Cen­ters that will focus on devel­op­ing evidence-based stan­darized sys­tem of care across 7 cat­e­gories of care. They will develop Read the rest of this entry »

Invitation to SharpBrains Summit — Technology for Cognitive Health and Performance

We are excited to invite you to the first vir­tual, global Sharp­Brains Sum­mit (Jan­u­ary 18-20th, 2010). The Sharp­Brains Sum­mit will fea­ture a sharpbrains_summit_logo_webdream team of over 25 speak­ers who are lead­ers in indus­try and research from 7 coun­tries, to dis­cuss emerg­ing research, tools and best prac­tices for cog­ni­tive health and per­for­mance. This inau­gural event will expose health and insur­ance providers, devel­op­ers, inno­va­tors at For­tune 500 com­pa­nies, investors and researchers, to the oppor­tu­ni­ties, part­ner­ships, trends, and stan­dards of the rapidly evolv­ing cog­ni­tive fit­ness field.

Reg­is­ter Today

Learn more and reg­is­ter Here today, at dis­counted early-bird rates, to receive these benefits:

  • Learn: Full access to all Con­fer­ence live ses­sions, and Down­load­able Record­ings and Handouts
  • See: lat­est tech­nolo­gies and prod­ucts dur­ing Expo Day
  • Con­nect and Dis­cuss: become a mem­ber of the Sharp­Brains Net­work for Brain Fit­ness Inno­va­tion (members-only LinkedIn Group) through the end of 2010, access online chats dur­ing the sum­mit, meet other reg­is­trants in your city
  • Under­stand the Big Pic­ture: access 10 Research Exec­u­tive Briefs pre­pared by lead­ing scientists

On top of those early-bird dis­counts, we offer an addi­tional 15% dis­count for Sharp­Brains read­ers who want Reg­u­lar Admis­sion. Dis­count code: sharp2010. You can reg­is­ter Here.

Agenda/ Speak­ers

Mon­day, Jan­u­ary 18th, 2010:

(Pre­lim­i­nary sched­ule, US Pacific Time)

8–9.15am. Cog­ni­tion & Neu­ro­plas­tic­ity: The New Health­care Frontier

  • Alvaro Fer­nan­dez, SharpBrains
  • David White­house, OptumHealth Behav­ioral Solutions
  • William Reich­man, Baycrest
  • P Murali Doraiswamy, Duke University

9.30-11am. Tools for Safer Dri­ving: The Oppor­tu­nity with Teenagers and Adults

  • Steven Aldrich, Posit Science
  • Shlomo Breznitz, CogniFit
  • Jerri Edwards, Uni­ver­sity of South Florida
  • Peter Chris­tian­son, Young Dri­vers of Canada

Noon-1.30pm. Baby Boomers and Beyond: Main­tain­ing Cog­ni­tive Vitality

Update: 15 FAQs on Neuroplasticity/ Brain Plasticity

Here you have the Octo­ber edi­tion of our monthly newslet­ter cov­er­ing cog­ni­tive health and brain fit­ness topics.

We recently run an online sur­vey among sub­scribers of our monthly eNewslet­ter, and over 500 peo­ple 107px-gray1197thumbnailsaid we have helped them make bet­ter per­sonal or pro­fes­sional deci­sions on how to main­tain and improve brain fit­ness. Respon­dents also had many good ques­tions to ask, so I have selected 15 com­mon ones, paraphrased/ syn­the­sized them below, and answered them by link­ing to our most rel­e­vant posts and resources. I hope you enjoy the FAQ session.

Q: I teach a brain fit­ness class at my library/ senior center/ school, using much of your info. Can you share some of your pre­sen­ta­tions?
A: Yes, we have just decided to share, using a Cre­ative Com­mons Attri­bu­tion No Deriv­a­tives License, the full pre­sen­ta­tion of my recent book talk at New York Pub­lic Library (opens video in YouTube). As long as you give credit to Sharp­Brains and don’t mod­ify it, you are free to use the pre­sen­ta­tion you can view and down­load HERE.

Q: What exactly does neu­ro­plas­tic­ity neuronsmean, and why is it so impor­tant for edu­ca­tion and health?
A: Start by read­ing how learn­ing changes your brain.

Q. Is this only rel­e­vant for older adults? Can I also apply it in the work­place (I am 47)
A. I strongly sus­pect you do have a human brain, so you may ben­e­fit from these Ten Habits of Highly Effec­tive Brains. Fur­ther, HR depart­ments would do well to start pay­ing more atten­tion to Cog­ni­tive Fit­ness and the Mature Work­force trends.

Q. I read so many con­flict­ing things I don’t know where to start.
A. You are not alone. We should all be aware that It is Not Only Cars That Deserve Good Main­te­nance: Brain Care 101.

Q. How can my orga­ni­za­tion deliver brain fit­ness activ­i­ties as a com­mu­nity ser­vice?
A. These arti­cles will pro­vide good guide­lines and ideas: Retool­ing Use It or Lose It , and Pub­lic Libraries: Community-Based Health Clubs for the Brain.

Q. Every­one seems obsessed with brain games. What about med­i­ta­tion?
A. Check out Yes, You Can Build Willpower, and Mind­ful­ness Med­i­ta­tion in Schools.

Q. Are software-based cog­ni­tive inter­ven­tions effec­tive?
A. As a cat­e­gory, it cer­tainly seems so, as long as we ask the right ques­tions, For Whom, For What?. For exam­ple, did you see this Sci­ence paper on how Cog­ni­tive Train­ing Can Influ­ence Dopamine Sys­tem?.

Q. What about the trade-off between time invested vs ben­e­fits real­ized.
A. Effi­ciency and replic­a­bil­ity of cog­ni­tive and brain-based out­comes seem to be, in fact, the strongest points of struc­tured cog­ni­tive inter­ven­tions. They seem to max­i­mize the Cog­ni­tive Value of your Men­tal Work­out.


Q. It some­times looks like the whole field came out of nowhere, due to Nin­tendo Brain Age’s suc­cess, so we can’t be talk­ing about some­thing seri­ous.

A: Nin­tendo did indeed cre­ate con­sumer aware­ness (for a prod­uct with lit­tle evi­dence) but “brain train­ing” has solid roots in neu­ropsy­chol­ogy and cog­ni­tive neu­ro­science, as you can read in our inter­view with Elkhonon Gold­berg.

Q. What about neu­ro­feed­back?
A. After years of much clin­i­cal use and lit­tle solid evi­dence, sev­eral impor­tant tri­als have been pub­lished since 2009, show­ing how neu­ro­feed­back can help diag­nose and treat ADHD patients, for exam­ple.

Q. How can one improve mem­ory?

A. Well, the answer deserves a whole book, but we can offer some Tips to Improve Mem­ory includ­ing Sleep, Prac­tice and Test­ing.

Q. How can I sharpbrainschecklist.thumbnailchoose one among the num­ber of prod­ucts mak­ing mem­ory and brain claims?
A. We sug­gest you use this Eval­u­a­tion check­list, and con­sider read­ing our con­sumer guide/ book.

Q. Any gen­eral tips for edu­ca­tors and life­long learn­ers?
A. Indeed, here you have these 10 Brain Tips to Teach and Learn.

Q. How can I keep track of all the new SharpBrains_State2009_Infographictrends, com­pa­nies and prod­ucts? Our health system/ insurer/ senior community/ ven­ture firm/ com­pany needs to make good deci­sions.
A. Well, that’s why we pub­lish mar­ket research, such as the one sum­ma­rized in this Info­graphic: State of the Mar­ket 2009 and also recently launched a pro­fes­sional Net­work for Brain Fit­ness Inno­va­tion.

Q: Thank you for all the infor­ma­tion you provide…but what I want more of is… brain teasers!
A. Under­stood. We will make sure to offer more, but you can try, right now, these Top 50 Brain Teasers and con­tinue with more recent puz­zles and brain games.

Cognitive Enhancement via Pharmacology AND Neuropsychology, in The New Executive Brain

(Editor’s Note: given the grow­ing media atten­tion to three appar­ently sep­a­rate worlds –cog­ni­tive enhance­ment via drugs, brain fit­ness train­ing soft­ware, com­put­er­ized neu­rocog­ni­tive assessments-, I found it refresh­ing to see our co-founder Elkhonon Gold­berg intro­duce the topic of cog­notropic drugs with an inte­gra­tive per­spec­tive in the much updated new edi­tion of his clas­sic book, now titled The New Executive Brain - By Elkhonon Goldberg The New Exec­u­tive Brain: Frontal Lobes In A Com­plex World. Below goes an excerpt).

For many neu­ropsy­chol­o­gists, like myself, sci­ence is a labor of love, but see­ing patients is bread and but­ter. Tra­di­tion­ally, the clin­i­cal con­tri­bu­tion of neu­ropsy­chol­ogy has been mostly diag­nos­tic, with pre­cious lit­tle to offer patients by way of treat­ment. Neu­ropsy­chol­ogy is not the only clin­i­cal dis­ci­pline for years con­signed to help­less voyeurism. Every dis­ci­pline con­cerned with cog­ni­tion shares this hum­bling predica­ment. A psy­chi­a­trist treat­ing a schiz­o­phrenic patient or a depressed patient finds him– or her­self in a sim­i­lar posi­tion. There are ample phar­ma­co­log­i­cal tools to treat the patient’s psy­chosis or mood, but very few to treat the patient’s cog­ni­tion. Even though psy­chi­a­trists increas­ingly rec­og­nize that cog­ni­tive impair­ment is often more debil­i­tat­ing in their patients than psy­chosis or mood dis­or­der, tra­di­tion­ally, very lit­tle direct effort has been aimed at improv­ing cognition.

A neu­rol­o­gist treat­ing a patient recov­er­ing from the effects of head injury does not fare much bet­ter. There are ade­quate means to con­trol the patient’s seizures but not his or her cog­ni­tive changes, despite the fact that cog­ni­tive impair­ment is usu­ally far more debil­i­tat­ing than an occa­sional seizure. Soci­ety has been so pre­oc­cu­pied with sav­ing lives, treat­ing hal­lu­ci­na­tions, con­trol­ling seizures, and lift­ing depres­sion that cog­ni­tion (mem­ory, atten­tion, plan­ning, prob­lem solv­ing) has been largely ignored. Granted, var­i­ous neu­rolep­tics, anti­con­vul­sants, anti­de­pres­sants, seda­tives, and stim­u­lants do have an effect on cog­ni­tion, but it is an ancil­lary effect of a drug designed to treat some­thing else.

Alzheimer’s dis­ease and other demen­tias have been society’s wake-up call. Here, in the most afflu­ent coun­try in the most afflu­ent of times, human minds were suc­cumb­ing to decay before human bod­ies, a sharp chal­lenge to the tacit pop­u­lar belief that the “body is frail but soul is for­ever.” This pro­vided an impe­tus for the devel­op­ment of an entirely new class of drugs, which can be termed famil­ially as “cog­notropic.” Their pri­mary and explicit pur­pose is to improve cognition.

Since med­ical and pub­lic pre­oc­cu­pa­tion with demen­tia focuses on mem­ory, most of the phar­ma­co­log­i­cal efforts have been directed at improv­ing mem­ory. At the time of this writ­ing, a hand­ful of drugs known as “Alzheimer’s drugs” or “mem­ory enhancers” have been approved by the U.S. Food and Drug Admin­is­tra­tion (FDA). In real­ity, both des­ig­na­tions are some­what mis­lead­ing. The drugs in ques­tion are Read the rest of this entry »

Why computerized neuropsychological tests will become routine — chemo brain example

Good arti­cle today in the NYT on “chemo brain” — some typ­i­cal short-term and long-term cog­ni­tive con­se­quences of chemotherapy.

The Fog That Fol­lows Chemother­apy (New York Times)

One quote is crit­i­cal — for chemo brain and also for a vari­ety of clin­i­cal con­di­tions that present asso­ci­ated cog­ni­tive impairments:

Con­trol­ling for brain func­tion before can­cer treat­ment begins can help deter­mine cause and effect. In one study, can­cer patients took a bat­tery of neu­ropsy­cho­log­i­cal tests before start­ing chemother­apy, three weeks after com­plet­ing treat­ment, and again one year later. Although a third of the patients had signs of cog­ni­tive impair­ment before ther­apy began, the num­ber jumped to 61 per­cent after treat­ment, and half remained impaired a year later.”

As we have dis­cussed before, I believe that inex­pen­sive com­put­er­ized cog­ni­tive assess­ments will start to become widely avail­able in only a few years, to help set up indi­vid­u­al­ized cog­ni­tive base­lines and inform clin­i­cal diag­noses and treat­ments. For more, you can read Com­put­er­ized Cog­ni­tive Assess­ments: oppor­tu­ni­ties and concerns

The Best Memory Tests: Mini-Mental and Beyond (Alzheimer’s Action Plan)

(Editor’s Note: I recently came across an excel­lent book and resource, The Alzheimer’s Alzheimer's Disease Action PlanAction Plan: The Experts’ Guide to the Best Diag­no­sis and Treat­ment for Mem­ory Prob­lems, recently released in paper­back. Dr. Murali Doraiswamy, one of the authors and lead­ing Alzheimer’s expert, kindly helped us cre­ate a 2-part arti­cle series to share with Sharp­Brains read­ers advice on a very impor­tant ques­tion, “How can we help the pub­lic at large to dis­tin­guish Alzheimer’s Dis­ease from nor­mal aging — so that an inter­est in early iden­ti­fi­ca­tion doesn’t trans­late into unneeded wor­ries?” What fol­lows is an excerpt from the book, pages 72–78, dis­cussing the Pros and Cons of the most com­mon assessments).

While no sin­gle test (other than a brain biopsy, which is a very inva­sive and risky pro­ce­dure) can con­clu­sively prove that a per­son has Alzheimer’s, many tests can give us a good idea. A list of all the tests that help us assess mem­ory and think­ing prob­lems appears at the end of this chap­ter. Mean­while, let’s take a good look at the whys and hows of a thor­ough mem­ory assessment.

WHAT A DIFFERENCE AN EXTRA TEST CAN MAKE

To under­stand why get­ting tested (and retested as symp­toms change and the dis­ease pro­gresses) is impor­tant, check out the expe­ri­ence of Kather­ine, who went to the doc­tor com­plain­ing of a mem­ory slow­down. She took five of the most impor­tant neu­ropsy­cho­log­i­cal tests, which assess brain func­tion with­out actu­ally phys­i­cally look­ing at the brain. Then she under­went brain scans, a car­dio­vas­cu­lar workup, and blood tests to see what else was going on that might be under­min­ing her men­tal func­tion. Read the rest of this entry »

References on Cognitive Health/ Brain Fitness

This is a par­tial list of the lit­er­a­ture we reviewed dur­ing the research phase of our new book, The Sharp­Brains Guide to Brain Fit­ness.  We know many friends of Sharp­Brains are researchers, health­care pro­fes­sion­als, graduate/ Ph.D. stu­dents, who want have direct access to the ref­er­ences (per­haps PubMed should pro­mote itself as a never end­ing source of men­tal stim­u­la­tion?), so here you have this list, orga­nized by rel­e­vant chap­ter. Please note that the list below appears in the book — whose man­u­script we had to close in Jan­u­ary 2009.

Intro­duc­tion

Basak, C. et al. (2008). Can train­ing in a real-time strat­egy video game atten­u­ate cog­ni­tive decline in older adults? Psy­chol­ogy and Aging.
Beg­ley, S. (2007). Train your mind, change your brain: How a new sci­ence reveals our extra­or­di­nary poten­tial to trans­form our­selves. Bal­lan­tine Books.
DeKosky, S. T., et al. (2008). Ginkgo biloba for pre­ven­tion of demen­tia: a ran­dom­ized con­trolled trial. Jour­nal of the Amer­i­can Med­ical Asso­ci­a­tion, 300, 2253–2262.
Doidge, N. (2007). The Brain that changes itself: Sto­ries of per­sonal tri­umph from the fron­tiers of brain sci­ence. Viking Adult.

Chap­ter 1. The Brain and Brain Fit­ness 101

Bunge, S. A., & Wright, S. B. (2007). Neu­rode­vel­op­men­tal changes in work­ing mem­ory and cog­ni­tive con­trol. Cur­rent Opin­ion In Neu­ro­bi­ol­ogy, 17(2), 243–50.
Dama­sio, A. (1995). Descartes error: Emo­tion, rea­son, and the human brain. Pen­guin Press.
David Kolb, D. (1983). Expe­ri­en­tial learn­ing: Expe­ri­ence as the source of learn­ing and devel­op­ment. FT Press.
Dra­gan­ski, B., Gaser, C., Kem­per­mann, G., Kuhn, H. G., Win­kler, J., Buchel, C., & May A. (2006). Tem­po­ral and spa­tial dynam­ics of brain struc­ture changes dur­ing exten­sive learn­ing. The Jour­nal of Neu­ro­science, 261231, 6314–6317.
Gage, F. H., Kem­per­mann, G., & Song, H. (2007). Adult Neu­ro­ge­n­e­sis. Cold Spring Har­bor Lab­o­ra­tory Press, NY.
Gard­ner, H. (1983). Frames of Mind: The the­ory of mul­ti­ple intel­li­gences. New York: Basic Books.
Gaser, C. & Schlaug, G. (2003). Brain struc­tures dif­fer between musi­cians and non-musicians. The Jour­nal of Neu­ro­science, 23, 9240–9245. Read the rest of this entry »

Neurocognitive assessments and sports concussions

Con­cus­sion effect ‘spans decades’ (BBC)

- “Peo­ple con­cussed in their youth show sub­tle signs of men­tal and phys­i­cal prob­lems even more than 30 years later, say Cana­dian researchers.”

- “Dr Louis de Beau­mont, who led the study, said: “This study shows that the effects of sports con­cus­sions in early adult­hood per­sist beyond 30 years post-concussion, and that it can cause cog­ni­tive and motor func­tion alter­ations as the ath­letes age.”

- “Ath­letes should be bet­ter informed about the cumu­la­tive and per­sis­tent effects of sports con­cus­sion on men­tal and phys­i­cal processes so they know about the risk asso­ci­ated with return­ing to their sport.”

The study in question:

De Beau­mont L, The­o­ret H, Mon­geon D at al. Brain func­tion decline in healthy retired ath­letes who sus­tained their last sports con­cus­sion in early adult­hood. Brain 2009, Advanced online pub­li­ca­tion Jan­u­ary 27

Given the impor­tance of this topic, which we cov­ered in our 2008 Mar­ket Research, we are happy to read about new resources like a new book titled Sports Neu­ropsy­chol­ogy: Assess­ment and Man­age­ment of Trau­matic Brain Injury

From a recent book review by Gary S. Solomon, Ph.D.:

- “The past 15 years has yielded an explo­sion of infor­ma­tion on Read the rest of this entry »

Meditation on the Brain: a Conversation with Andrew Newberg

Dr. Andrew New­berg is an Asso­ciate Pro­fes­sor in the Depart­ment of Radi­ol­ogy and Psy­chi­a­try and Adjunct Assis­tant Pro­fes­sor in the Depart­ment of Reli­gious Stud­ies at theAndrew Newberg Uni­ver­sity of Penn­syl­va­nia. He has pub­lished a vari­ety of neu­roimag­ing stud­ies related to aging and demen­tia. He has also researched the neu­ro­phys­i­o­log­i­cal cor­re­lates of med­i­ta­tion, prayer, and how brain func­tion is asso­ci­ated with mys­ti­cal and reli­gious experiences.

Dr. New­berg, thank you for being with us today. Can you please explain the source of your inter­ests at the inter­sec­tion of brain research and spirituality?

Since I was a kid, I had a keen inter­est in spir­i­tual prac­tice. I always won­dered how spir­i­tu­al­ity and reli­gion affect us, and over time I came to appre­ci­ate how sci­ence can help us explore and under­stand the world around us, includ­ing why we humans care about spir­i­tual prac­tices. This, of course, led me to be par­tic­u­larly inter­ested in brain research.

Dur­ing med­ical school I was par­tic­u­larly attracted by the prob­lem of con­scious­ness. I was for­tu­nate to meet researcher Dr. Eugene D’Aquili in the early 1990s, who had been doing much research on reli­gious prac­tices effect on brain since the 1970s. Through him I came to see that brain imag­ing can pro­vide a fas­ci­nat­ing win­dow into the brain.

Can we define reli­gion and spir­i­tu­al­ity –which sound to me as very dif­fer­ent brain processes-, and why learn­ing about them may be help­ful from a purely sec­u­lar, sci­en­tific point of view?

Good point, def­i­n­i­tions mat­ter, since dif­fer­ent peo­ple may be search­ing for God in dif­fer­ent ways. I view being reli­gious as par­tic­i­pat­ing in orga­nized rit­u­als and shared beliefs, such as going to church. Being spir­i­tual, on the other hand, is more of an indi­vid­ual prac­tice, whether we call it med­i­ta­tion, or relax­ation, or prayer, aimed at expand­ing the self, devel­op­ing a sense of one­ness with the universe.

What is hap­pen­ing is that spe­cific prac­tices that have tra­di­tion­ally been asso­ci­ated with reli­gious and spir­i­tual con­texts may also be very use­ful from a main­stream, sec­u­lar, health point of view, beyond those con­texts. Sci­en­tists are research­ing, for exam­ple, what Read the rest of this entry »

Welcome to SharpBrains!

As seen in The New York Times, The Wall Street Jour­nal, CNN and more, Sharp­Brains is an inde­pen­dent mar­ket research and inno­va­tion think tank track­ing brain fit­ness and applied neu­ro­plas­tic­ity research and mar­ket­place. AARP recently named The Sharp­Brains Guide to Brain Fit­ness a Best Book on the subject.

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Top 30 Articles

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  20. Dr. Elkhonon Gold­berg on Cog­ni­tive Train­ing and Brain Fit­ness, by Alvaro Fernandez
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