The Longevity Div­i­dend is a the­ory that says we hope to inter­vene sci­en­tif­i­cally to slow the aging process, which will also delay the onset of age-related dis­eases. Delay­ing aging just seven years would slash rates of con­di­tions like can­cer, dia­betes, Alzheimer’s dis­ease and heart dis­ease in half. That’s the longevity part.

The div­i­dend comes from the social, eco­nomic, and health bonuses that would then be avail­able to spend on schools, energy, jobs, infra­struc­ture tril­lions of dol­lars that today we spend on health­care ser­vices. In fact, at the rate we’re going, by the year 2020 one out of every $5 spent in this coun­try will be spent on health­care. Obvi­ously, some­thing has to change.

Enter the Longevity Div­i­dend. The Longevity Div­i­dend doesn’t sug­gest that we live longer; instead, it calls for liv­ing bet­ter. The idea is that if we use sci­ence to increase healthspan, not lifes­pan. In other words, tomor­rows 50-year-old would have the health pro­file of a 43-year-old.

It might sound like sci­ence fic­tion, but, in fact, it’s quite pos­si­ble. We’re already doing it in some ani­mal mod­els using genetic and dietary inter­ven­tions, tech­niques related to what sci­en­tists call “the biol­ogy of aging.”

Get­ting there in humans, how­ever, means embrac­ing an entirely new approach to our think­ing about dis­ease and aging, and how we con­duct sci­en­tific research into the two.

Get­ting Sci­en­tists’ Attention

A group of emi­nent researchers first pro­posed the Longevity Div­i­dend in a 2006 arti­cle pub­lished in The Sci­en­tist. The authors, S. Jay Olshan­sky, PhD, pro­fes­sor of epi­demi­ol­ogy and bio­sta­t­ics at the Uni­ver­sity of Illi­nois in Chicago, Daniel P. Perry, exec­u­tive direc­tor of the Alliance for Aging Research in Wash­ing­ton, DC, Richard A. Miller, MD, PhD, pro­fes­sor of pathol­ogy at the Uni­ver­sity of Michi­gan in Ann Arbor, and Robert N. But­ler, MD, pres­i­dent and CEO of the Inter­na­tional Longevity Cen­ter in New York, intended their essay to be a “gen­eral state­ment to sci­en­tists about the need for a par­a­digm shift in the way we think about aging and disease.

The researchers also met with U.S. sen­a­tors who served on the Sen­ate com­mit­tee that over­saw the bud­get for the National Insti­tutes of Health (NIH). “We told them we believed Read the rest of this entry »

Hiroshi Komiyama, Pres­i­dent of the Uni­ver­sity of Tokyo and Chair­per­son of the Global Agenda Coun­cil on the Chal­lenges of Geron­tol­ogy I am a mem­ber of, just pro­vided coun­cil mem­bers with a brief update of his par­tic­i­pa­tion in the recent World Eco­nomic Forum.

Part of the pro­ceed­ings are pub­lic — you may enjoy read­ing this panel write-up of the ses­sion Health­care under Stress:

- “Japan has the world’s old­est pop­u­la­tion. Health and longevity cre­ate wealth and, thus, “health begets wealth”. It is doc­u­mented that nations that develop a five-year life expectancy advan­tage also cre­ate a larger GDP. A healthy child­hood and adult­hood con­tribute to a more pro­duc­tive old age. New mar­kets and indus­tries are aris­ing – “sil­ver indus­tries” such as finan­cial ser­vices, health, hous­ing and hos­pi­tal­ity geared to senior cit­i­zens. Longevity needs to be linked to health – includ­ing cog­ni­tive health – and lifestyle choices play a major role in health.”

- “The pub­lic health focus is shift­ing from infec­tions to car­dio­vas­cu­lar dis­eases. Com­plex new mod­els are nec­es­sary to develop bet­ter responses and improved health – with the pri­mary empha­sis on “really good pri­mary health­care” and pre­ven­tion – to lower costs. Pre­ven­tion increases the healthy years of a person’s life. The chal­lenge is cre­at­ing the incen­tive for pre­ven­tion: how can peo­ple be encour­aged to make healthy choices? Mobi­lized pop­u­la­tions can drive the change. Fin­land has an 80% lower inci­dence of heart dis­ease than 30 years ago due to such incentives.”

Full write-up: Health­care under Stress

Related arti­cles:

- The Future of the Aging Soci­ety: Bur­den or Human Capital?

- Update: Global Con­sor­tium for Neu­rocog­ni­tive Fit­ness Innovation

Wel­come to the 61st edi­tion of Encephalon, the blog car­ni­val that offers some of the best neu­ro­science and psy­chol­ogy blog posts every other week.

We do have an excel­lent set of arti­cles today. cov­er­ing much ground. Enjoy the reading:

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Neu­ro­science and Society

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Alzheimer’s Dis­ease and Neu­rocog­ni­tive Health Read the rest of this entry »

Imag­ine see­ing a top sheik from Dubai, wrapped in tra­di­tional Arab cloth­ing, exclaim “Yes We Can” in front of the 800 experts gath­ered dur­ing the Sum­mit of the Global Agenda that just took place in Dubai, co-organized by the World Eco­nomic Forum and the Gov­ern­ment of Dubai. This same sheik added that “we build the future with our own hands”.

You can read more about the main points of the Global Agenda Coun­cils con­ver­sa­tion here: Dis­cus­sion High­lights. Below go some of my own still-jetlagged reflections.

The finan­cial cri­sis has made obvi­ous the obvi­ous: that we live in a truly new and global world.

And that busi­ness as usual will lead to global dis­as­ter — we need new approaches to col­lec­tively adapt to and thrive in this new envi­ron­ment. The answer is not to go back to any old par­a­digm, which sim­ply will not work in a new real­ity, but to imag­ine and build a bet­ter new way of doing things.

Some of the atten­dants urged us to “reboot” the sys­tem. I don’t think that a “reboot” is enough — we need to upgrade to a new oper­at­ing sys­tem. We can call it Planet Earth 2.0.Based on the group dis­cus­sion we had on Sun­day morn­ing, let me pro­pose some of the archi­tec­tural prin­ci­ples that should under­lie any emerg­ing Planet Earth 2.0 oper­at­ing sys­tem. Read the rest of this entry »

As men­tioned before, the World Eco­nomic Forum asked me to write “an 800 words sum­mary of your most com­pelling action­able idea on the chal­lenges of geron­tol­ogy”, in prepa­ra­tion for the Inau­gural Sum­mit of the Global Agenda that will take place Novem­ber 7 to 9th in Dubai.A good num­ber of Sharp­Brains read­ers and clients offered their insights — and expressed an inter­est in read­ing the draft. So below you have — a pro­posal to cre­ate a Global Con­sor­tium for Neu­rocog­ni­tive Fit­ness Inno­va­tion, build­ing on our exist­ing mar­ket research and advi­sory ser­vices work. Your thoughts?

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The Con­text

Grow­ing Demands on Our Brains: Pic­ture 6.7 bil­lion Prim­i­tive Brains inhab­it­ing a Knowl­edge Soci­ety where life­long learn­ing and mas­ter­ing con­stant change in com­plex envi­ron­ments are crit­i­cal for pro­duc­tive work, health and per­sonal fulfillment.

Wel­come to Planet Earth, 2008.

Fur­ther stretched by increased longevity: Now pic­ture close to 1 bil­lion of those brains over the age of 60 – and please remem­ber that, less than 100 years ago, life expectancy was between 30 to 40 years. The rapidly evolv­ing Knowl­edge Soci­ety is plac­ing new and enor­mous demands on our “prim­i­tive” human brains. And the longer our lifes­pans, the more obvi­ous the “cog­ni­tive gap”. Hence, from a health point of view, the grow­ing Read the rest of this entry »

Just saw a very inter­est­ing press release regard­ing computer-based neu­rocog­ni­tive assess­ments — a crit­i­cal part of the brain fit­ness puz­zle. How long will it take before con­sumers can have access to a reli­able and cred­i­ble annual “men­tal check-up”/ cog­ni­tive baseline?

Head­Min­der Cog­ni­tive Sta­bil­ity Index: Com­put­er­ized Neu­rocog­ni­tive … (Press release)

- “The Head­Min­der web-based Cog­ni­tive Sta­bil­ity Index (CSI) has proven more use­ful for blast-concussion detec­tion than the ANAM com­put­er­ized test bat­tery the DoD cur­rently employs. The CSI pro­vides an imme­di­ate solu­tion to clear the back­log of 400,000 IED-exposed ser­vice mem­bers in less than two years.”

- “The CSI is a 30-minute, Internet-based, com­put­er­ized test that pro­vides auto­mated, objec­tive mea­sures of atten­tion, mem­ory, response speed, and pro­cess­ing speed for ini­tial eval­u­a­tion of cog­ni­tive func­tion­ing. The CSI pro­duces stan­dard­ized reports that enable triage and decision-making appro­pri­ate to a user’s qual­i­fi­ca­tions — from medic to neu­ropsy­chol­o­gist to neu­rol­o­gist and other treat­ment team members.”

We cov­ered this emerg­ing type of assess­ments in the arti­cle Com­put­er­ized Cog­ni­tive Assess­ments: oppor­tu­ni­ties and concerns

- “In fact, one of the Read the rest of this entry »

Some very inter­est­ing brain fit­ness soft­ware mar­ket news:

1) Sci­en­tific Learn­ing To Buy Out Soliloquy

- “Sci­en­tific Learn­ing Corp. has announced that it will acquire Solil­o­quy Learn­ing from JTT Hold­ings. Both Sci­en­tific Learn­ing and Solil­o­quy pro­vide tech­nol­ogy solu­tions for edu­ca­tion. The acqui­si­tion will cost SLC about $11 mil­lion and is expected to be com­pleted this month.”

- “Sci­en­tific Learn­ing is the devel­oper of Fast For­Word, a fam­ily of read­ing inter­ven­tion tools tar­geted toward stu­dents who are char­ac­ter­ized as strug­gling learn­ers and designed to develop the required “neu­rocog­ni­tive skills” for read­ing and learn­ing in gen­eral. Solil­o­quy is also a read­ing inter­ven­tion developer.”

Com­ment: this acqui­si­tion con­sol­i­dates Sci­en­tific Learn­ing (NSDQ: SCIL) as the lead­ing com­pany in the edu­ca­tion seg­ment of the brain fit­ness mar­ket. It will be inter­est­ing to track what research gets done on the neural and cog­ni­tive effects of Solil­o­quy, since Sci­en­tific Learning’s Fast For­word is backed by exten­sive literature.

2) Tech­no­me­dia Part­ners With SBT to Accel­er­ate Its Inter­na­tional Expansion

- “Tech­no­me­dia, a Cana­dian provider of tal­ent man­age­ment and human cap­i­tal devel­op­ment solu­tions, announced its part­ner­ship with the SBT (Sci­en­tific Brain Train­ing) group, a Euro­pean provider of train­ing and eval­u­a­tion of cog­ni­tive func­tions.” Read the rest of this entry »