I first dis­cov­ered Nor­man Doidge’s book, The Brain That Changes Itself, in a May, 2007 review in the New York Times. Intrigued, but caught up in myr­iad end-of-school-year respon­si­bil­i­ties, the book was put out of my mind until later that sum­mer, when our schools learn­ing spe­cial­ist emailed to say she had just fin­ished a fas­ci­nat­ing book. The Brain That Changes Itself: Stores of Per­sonal Tri­umph from the Fron­tiers of Brain Sci­ence, is a com­pelling col­lec­tion of tales about the amaz­ing abil­i­ties of the brain to rewire, read­just and relearn after hav­ing a slice of itself ren­dered dys­func­tional. The first seven chap­ters cap­ti­vated me for their per­sonal sto­ries; the final four chap­ters for the sci­ence and philosophy.

Part of what makes Doidge’s writ­ing so acces­si­ble is he tells sto­ries, and his sto­ries just hap­pen to incor­po­rate brain sci­ence. As a result, his book is easy to digest. The neu­ro­science behind Doidge’s book involves neu­ro­plas­tic­ity, which is the brain’s abil­ity to rewire itself. This means that the brain is our intel­li­gence  is not some­thing fixed in con­crete but rather a chang­ing, learn­ing entity. On the face of it, this con­cept should not sound unusual, for it is what hap­pens to indi­vid­u­als all the time as we go about the learn­ing process, from infancy onwards.

What sep­a­rates the sto­ries in this book from daily learn­ing is that Read the rest of this entry »

Two quick notes:

- Encephalon #56 edi­tion: the lat­est edi­tion of this neu­ro­science and psy­chol­ogy blog car­ni­val is ready for your read­ing plea­sure.
- Michael Merzenich Elected to Insti­tute of Med­i­cine: Con­grat­u­la­tions! “The Insti­tute of Medicine’s total active mem­ber­ship is now 1,576 and the num­ber of for­eign asso­ciates is 89. With another 71 mem­bers hold­ing emer­i­tus sta­tus, IOM’s total mem­ber­ship is now 1,736. Estab­lished in 1970 by the National Acad­emy of Sci­ences, the Insti­tute of Med­i­cine is a national resource for inde­pen­dent, sci­en­tif­i­cally informed analy­sis and rec­om­men­da­tions on issues related to human health. With their elec­tion, mem­bers make a com­mit­ment to devote a sig­nif­i­cant amount of vol­un­teer time as mem­bers of IOM study com­mit­tees.“
You may have seen him talk­ing about neu­ro­plas­tic­ity in the PBS spe­cial titled Brain Fit­ness Program.

Back in July, I wrote a post enti­tled 10 Brain Tips To Teach and Learn. Those tips apply to stu­dents of any age, includ­ing adults, for ide­ally adults are still learn­ers. Why is adult learn­ing rel­e­vant in a brain-focused blog, you may wonder:

The short of it

As we age, our brain:

still forms new brain cells
can change its struc­ture & func­tion
finds pos­i­tive stress can be ben­e­fi­cial; neg­a­tive stress can be detri­men­tal
can thrive on novel chal­lenges
needs to be exer­cised, just like our bodies

The long of it

Adults may have a ten­dency to get set in their ways have been doing it this way for a long time and it works, so why change? Turns out, though, that change can be a way to keep aging brains healthy. At the April Learn­ing & the Brain con­fer­ence, the theme of which was neu­ro­plas­tic­ity, I attended sev­eral ses­sions on adult learn­ing. Here’s what the experts are saying.

Read the rest of this entry »

Thanks to our 3-month-old daugh­ter, my wife and I have been learn­ing much about baby brains. Mostly learn­ing on the job, as you can imagine.

We just watched a very nice PBS series titled Secret Life of the Brain that cov­ers brain devel­op­ment across the lifes­pan: babies, kids, teenagers, adults, seniors. A bit dated (2002) but excel­lent watch­ing even today.

Read the rest of this entry »

Quick link to an excel­lent and inspir­ing arti­cle in the Wall Street Jour­nal: 12 Peo­ple Who Are Chang­ing Your Retire­ment
(open access dur­ing a week)

Read the rest of this entry »

The most pop­u­lar ques­tion we got when we announced that PBS had a great spe­cial on Brain Fit­ness Pro­gram and Neu­ro­plas­tic­ity in Decem­ber was, when will the DVD be available?

Well, finally here it comes. You can click on the image or the title to go over to PBS shop to learn more and buy it.

The Brain Fit­ness Pro­gram DVD ($24.95, shipped by 02/01/08). “This pro­gram presents a work­out to help view­ers get their brains in bet­ter shape. The Brain Fit­ness Pro­gram is based on neuro-plasticity, the abil­ity of the brain to change and adapt — even rewire itself. In the past two years, a team of sci­en­tists has devel­oped computer-based stim­u­lus sets that drive ben­e­fi­cial chem­i­cal, phys­i­cal and func­tional changes in the brain. Dr. Michael Merzenich of the Uni­ver­sity of Cal­i­for­nia San Fran­cisco and his col­leagues around the world have been lead­ing this effort; he brings the research find­ings, along with a sci­en­tif­i­cally based set of brain exer­cises, to PBS view­ers in this inno­v­a­tive and life-altering pro­gram. Peter Coy­ote narrates. ”

To pur­chase: click Here.

You can watch a 3-minute trailer: click here.

———-

Note: How can any­one take care of his or her brain when every week brings a new bar­rage of arti­cles and stud­ies which seem to con­tra­dict each other?

Do sup­ple­ments improve mem­ory? Do you need both phys­i­cal and men­tal exer­cise –or is one of them enough? Why is man­ag­ing stress so impor­tant to atten­tion and mem­ory? Which brain train­ing approach, if any, is worth one’s time and money?

If you have these ques­tions, check out this new book, The Sharp­Brains Guide to Brain Fit­ness:

Order Book at Amazon.com
	Click Here to order at Amazon.com. Print Edi­tion, $24.95

Order Kin­dle Edi­tion
	Click Here to order at Amazon.com, Kin­dle Edi­tion, $9.99

Sharon Beg­ley, Newsweek’s sci­ence reporter, recently wrote that

- “With the nation’s 78 mil­lion baby boomers approach­ing the age of those dreaded ‘“where did I leave my keys?” moments, it’s no won­der the mar­ket for computer-based brain train­ing has shot up from essen­tially zero in 2005 to $80 mil­lion this year, accord­ing to the con­sult­ing firm SharpBrains.

- “Now comes the largest and most rig­or­ous study of a commercially-available train­ing pro­gram, and it shows that there is hope for aging brains. This morn­ing, at the meet­ing of the Geron­to­log­i­cal Soci­ety of Amer­ica, sci­en­tists are pre­sent­ing data show­ing that after eight weeks of daily one-hour ses­sions with Brain Fit­ness 2.0 from Posit Sci­ence, elderly vol­un­teers got mea­sur­ably bet­ter in their brain’s speed and accu­racy of processing.

We recently had the chance to inter­view Dr. Eliz­a­beth Zelin­ski of the Uni­ver­sity of South­ern Cal­i­for­nia Andrus Geron­tol­ogy Cen­ter, who led the IMPACT (Improve­ment in Mem­ory with Plasticity-based Adap­tive Cog­ni­tive Train­ing) Study Sharon Beg­ley refers to in the quote above.

First, some con­text on this study, which is by far the largest high-quality study of its kind. The study was prospec­tive, ran­dom­ized, con­trolled, and used a dou­ble blind trial. 524 healthy adults 65-year-old and over were divided into two groups. One received an hour a day of train­ing for eight to ten weeks, and the other spent the same amount of time watch­ing edu­ca­tional DVDs. The IMPACT study, funded by Posit Sci­ence cor­po­ra­tion, was per­formed in mul­ti­ple loca­tions, includ­ing the Mayo Clinic, USCF, and San Fran­cisco Vet­eran Affairs Med­ical Center.

The dis­cus­sion cen­ters at his point on the ini­tial results that were pre­sented Geron­to­log­i­cal Soci­ety of Amer­ica (the study hasn’t been pub­lished yet).

Alvaro Fer­nan­dez: Dr. Zelin­ski. Thank you for being with us. Could you start by set­ting the con­text and pro­vid­ing an overview of how human cog­ni­tive abil­i­ties typ­i­cally evolve as we age based on insights from your Long Beach Lon­gi­tu­di­nal Study?

Eliz­a­beth Zelin­ski: Of course. The first con­cept to under­stand is that dif­fer­ent cog­ni­tive skills evolve over the lifes­pan in dif­fer­ent ways. Some that rely on expe­ri­ence, such as vocab­u­lary, actu­ally improve as we age. Some tend to decline grad­u­ally, start­ing in our late 20s. This hap­pens, for exam­ple, with pro­cess­ing speed (how long it takes us to process and respond to infor­ma­tion), mem­ory, and rea­son­ing. We could sum­ma­rize this phe­nom­e­non by say­ing that as we age we get bet­ter at deal­ing with the famil­iar, but worse at deal­ing with the new. We can always learn, but at a slower pace.

Are there any spe­cific tip­ping or inflec­tion points in this trend, any age when the rate of decline is more pronounced?

We don’t have a clear answer to that. It depends a lot on the indi­vid­ual. In gen­eral it is a grad­ual, cumu­la­tive process, so that by age 70 we sta­tis­ti­cally see clear age declines. Which, for exam­ple, is a strong fac­tor deter­min­ing why older adults strug­gle to adapt to new tech­nolo­gies, but why try­ing to learn them pro­vides needed men­tal stim­u­la­tion. Now we know that genes only account for a por­tion of this decline. Much of it depends on our envi­ron­ment, lifestyle and actions.

Can you sum­ma­rize what a healthy indi­vid­ual can do to slow down this process of decline, and help stay healthy and pro­duc­tive as long as possible?

One gen­eral rec­om­men­da­tion is to do every­thing we can to pre­vent or delay dis­ease processes, such as dia­betes or high-blood pres­sure, that have a neg­a­tive effect on our brains. For exam­ple, it is a tragedy in our soci­ety that we usu­ally reduce our lev­els of phys­i­cal exer­cise dras­ti­cally after we leave school.

Let me then ask: what are the rel­a­tive virtues of phys­i­cal vs. men­tal exercise?

Great ques­tion! That in fact leads into my sec­ond rec­om­men­da­tion. Aer­o­bic exer­cise has been shown to Read the rest of this entry »

Update (11/10/10): Have you seen PBS great spe­cials on Brain Fit­ness and Neu­ro­plas­tic­ity ?

The Brain Fit­ness Pro­gram DVD ($24.95)

“The Brain Fit­ness Pro­gram is based on the brain’s abil­ity to change and adapt, even rewire itself. In the past two years, a team of sci­en­tists has devel­oped computer-based stim­u­lus sets that drive ben­e­fi­cial chem­i­cal, phys­i­cal and func­tional changes in the brain. Dr. Michael Merzenich of the Uni­ver­sity of Cal­i­for­nia and his col­leagues share their sci­en­tif­i­cally based set of brain exer­cises in this life-altering pro­gram. Peter Coy­ote (pic­tured) narrates. ”

PBS aired in Decem­ber 2007 a spe­cial pro­gram on neu­ro­plas­tic­ity, brain fit­ness, aging and the brain titled “Brain Fit­ness Pro­gram”. To watch the 3-minute trailer: click here.

In 2008, PBS released a sec­ond DVD:

Brain Fit­ness 2: Sight and Sound DVD ($24.95)

“This pro­gram, specif­i­cally designed to help peo­ple get the most from their vision and hear­ing as they age, con­sid­ers how these senses change through­out life and what peo­ple can do to keep them healthy and fully functional.”

.

If you do not have time to watch these great doc­u­men­taries, here are a few points one needs to under­stand about neuroplasticity:

1.  The human brain is now con­sid­ered to be a highly dynamic and con­stantly reor­ga­niz­ing sys­tem capa­ble of being shaped and reshaped across an entire lifes­pan. It is believed that every expe­ri­ence alters the brain’s orga­ni­za­tion at some level. The key words in this new approach to the brain are neu­ro­plas­tic­ity and neu­ro­ge­n­e­sis. Neu­ro­plas­tic­ity refers to the life­long capac­ity of the brain to change and rewire itself in response to the stim­u­la­tion of learn­ing and expe­ri­ence. Neu­ro­ge­n­e­sis is the abil­ity to cre­ate new neu­rons and con­nec­tions between neu­rons through­out a life­time. The lat­ter process is also referred to as synap­to­ge­n­e­sis. This new par­a­digm con­trasts with tra­di­tional ideas of the human brain being a fixed and essen­tially lim­ited sys­tem that only degrades with age.

2. As we age, the rate of change in the brain, or neu­ro­plas­tic­ity, declines but does not come to a halt. In addi­tion, we now know that new neu­rons can appear in cer­tain parts of the brain up until the day we die.

3. Brain plas­tic­ity is cru­cial fol­low­ing head injury. It is the one brain’s abil­ity that allows recov­ery. Brain plas­tic­ity is also the abil­ity that brain train­ing takes advan­tages of to try to slow down the aging process.

To read about evi­dence of neu­ro­plas­tic­ity in the human brain take a look at Brain plas­tic­ity: How learn­ing changes you brain

———-

Note: How can any­one take care of his or her brain when every week brings a new bar­rage of arti­cles and stud­ies which seem to con­tra­dict each other?

Do sup­ple­ments improve mem­ory? Do you need both phys­i­cal and men­tal exer­cise –or is one of them enough? Why is man­ag­ing stress so impor­tant to atten­tion and mem­ory? Which brain train­ing approach, if any, is worth one’s time and money?

If you have these ques­tions, check out this new book, The Sharp­Brains Guide to Brain Fit­ness:

The Sharp­Brains Guide to Brain Fit­ness
	Click Here to order at Amazon.com. Print Edi­tion, $24.95

	Click Here to order at Amazon.com, Kin­dle Edi­tion, $9.99

We finally had time to hear and enjoy the 35-minute inter­view with WSJ sci­ence writer Sharon Beg­ley about her new book, Train Your Mind Change Your Brain. Highly rec­om­mended. (Thanks Beate!)

NPR Talk of the Nation, Feb­ru­ary 2, 2007: “For years, sci­en­tists believed the brain’s struc­ture couldn’t be changed. The new sci­ence of neu­ro­plas­tic­ity says that’s not the case, and argue the brain is much more flex­i­ble than pre­vi­ously thought.”

Lis­ten to the inter­view here.