Build­ing Blocks for a Bet­ter Future

The best alter­na­tive for tomor­row should be bet­ter than the best alter­na­tive avail­able today. How do we get there, when “cog­ni­tion” and “brain fit­ness” remain elu­sive con­cepts in pop­u­lar cul­ture? I believe that the lack of pub­lic edu­ca­tion is the major obsta­cle that lim­its the brain fit­ness field’s poten­tial to deliver real-world ben­e­fits, since only informed demand will ensure the ongo­ing devel­op­ment of ratio­nal, struc­tured “rules of the road.” What could be done to address this and other par­tic­u­lar obsta­cles? Read the rest of this entry »

Engag­ing peo­ple where they are in the life-course

Eighty per­cent of the 38,000 adults over age 50 who were respon­ders in the 2010 AARP Mem­ber Opin­ion Sur­vey indi­cated “stay­ing men­tally sharp” was their top ranked inter­est and con­cern (Dinger, 2010). What exactly does this phrase mean? And what role can tech­nol­ogy play in “stay­ing men­tally sharp”? Intel CEO Paul Otellini has said, “You have to start by think­ing about what peo­ple want to do… and work back­ward.” Read the rest of this entry »

The ter­mi­nol­ogy “fun­da­men­tal attri­bu­tion error” describes the ten­dency to over­value personality-based expla­na­tions for observed human behav­iors, while under­valu­ing sit­u­a­tional expla­na­tions for those behav­iors.  I believe that a pri­mary rea­son behind many per­ceived and real eth­i­cal chal­lenges in the brain fit­ness field is due not so much to cer­tain stake­hold­ers’ lack of per­sonal or pro­fes­sional ethics, but derives from the flawed soci­etal con­struct that under­pins cur­rent, rel­e­vant inno­va­tions. To improve the ethics of the brain fit­ness busi­ness and its appli­ca­tion (and empower con­sumers’ informed deci­sion mak­ing), there must first be agree­ment about a mean­ing­ful, appro­pri­ate way to ana­lyze and guide inno­va­tion. This is the crux of the prob­lem. The cur­rent med­ical model is not up to the task at hand, since it is heav­ily skewed toward inva­sive drugs and devices dri­ven by disease-based mod­els, and fails to lever­age Read the rest of this entry »

(Editor’s Note: I recently came across an excel­lent book and resource, The Alzheimer’s Action Plan: The Experts’ Guide to the Best Diag­no­sis and Treat­ment for Mem­ory Prob­lems, just released in paper­back. Dr. Murali Doraiswamy, one of the authors and lead­ing Alzheimer’s expert, kindly helped us cre­ate a 2-part arti­cle series to share with Sharp­Brains read­ers advice on a very impor­tant ques­tion, “How can we help the pub­lic at large to dis­tin­guish Alzheimer’s Dis­ease from nor­mal aging — so that an inter­est in early iden­ti­fi­ca­tion doesn’t trans­late into unneeded wor­ries?” What fol­lows is an excerpt from the book, pages 3–8).

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As it turns out, Jane did not have Alzheimer’s. She con­sulted a doc­tor, who, in doc­s­peak, told her that the pas­sage of time (get­ting older) had taken a slight toll on her once-superquick mem­ory. She was slow­ing down a lit­tle, and if she relaxed, the name or date or other bit of infor­ma­tion she needed would come to her soon enough. She was still good at her job and home life. She had sim­ply joined the ranks of the wor­ried well.

Nor­mal brain aging, begin­ning as early as the for­ties in some peo­ple, may include:

• Tak­ing longer to learn or remem­ber information
• Hav­ing dif­fi­culty pay­ing atten­tion or con­cen­trat­ing in the midst of distractions
• For­get­ting such basics as an anniver­sary or the names of friends
• Need­ing more reminders or mem­ory cues, such as promi­nent appoint­ment cal­en­dars, reminder notes, a phone with a well­stocked speed dial

Although they may need some assis­tance, older peo­ple with­out a men­tal dis­or­der retain their abil­ity to do their errands, han­dle money, find their way to famil­iar areas, and behave appropriately.

How does this com­pare to a per­son with Alzheimer’s? When Alzheimer’s slows the brain’s machin­ery, peo­ple begin to lose their abil­ity to Read the rest of this entry »

What started as an aca­d­e­mic dis­pute regard­ing dis­clo­sure of con­flict of inter­est is now snow­balling into the main­stream media, due to the over-reaction by JAMA edi­tors as reported in this Wall Street Jour­nal blog post, JAMA edi­tor calls Critic a “Nobody and a Noth­ing”

In sum­mary, Dr. Jonathan Leo, the “Critic”, dared to draw atten­tion to 2 impor­tant points regard­ing a study com­par­ing the effi­cacy of ther­apy vs. med­ica­tion pub­lished in the Jour­nal of the Amer­i­can Acad­emy of Med­i­cine (JAMA) — one of the most pres­ti­gious sci­en­tific publications:

1) The study results were pre­sented and reported in a biased way, since they favored one spe­cific inter­ven­tion, a drug, while ignor­ing another one, therapy-based, that had equally sta­tis­ti­cally sig­nif­i­cant effects.

2) Both the lead author of the study and one of the main experts asked to com­ment on the study in sev­eral media out­lets had undis­closed and unre­ported con­flicts of inter­est. JAMA could have done a 5-minute Google search to iden­tify and report the con­flict of inter­est of the lead author (received a vari­ety of rev­enues from the drugmaker).

Dr. Leo has sum­ma­rized the con­tin­u­ing mat­ter in sev­eral impres­sive let­ters. The 2 main ones, in chrono­log­i­cal order:

Clin­i­cal Tri­als of Ther­apy vs. Med­ica­tion: Even in a Tie, Med­ica­tion Wins(BMJ)

- “Cen­tral to the idea of evidence-based med­i­cine is that the choices made by patients and doc­tors to use a cer­tain treat­ment should at least in part be based on sci­en­tific stud­ies pub­lished in peer reviewed aca­d­e­mic jour­nals. For a patient diag­nosed with Read the rest of this entry »

Not a day goes by with­out a sig­nif­i­cant depression-related announce­ment. Yes­ter­day, one could read that Older Women More Likely to Suf­fer Depres­sion (than Older Men; in the Wash­ing­ton Post). Today, we see that St. Jude Start­ing Trial On Brain Stim­u­la­tion For Depres­sion (CNN). A few days ago, Blue Cross of Cal­i­for­nia Launched Mater­nity Depres­sion Pro­gram (press release).

Time to step back and ask our­selves ques­tions such as, “What is going On”, “What is Depres­sion”, “What Treat­ments Work, and What is the Lat­est Research”. For­tu­nately, thanks to our col­lab­o­ra­tion with Greater Good Mag­a­zine, Jill Sut­tie offers a fas­ci­nat­ing answers to those questions-and more. Enjoy.

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Clos­ing the Circuit

Helen Mayberg’s research could rev­o­lu­tion­ize depres­sion treatment.

— By Jill Suttie.

At some point in their lives, 5 to 12 per­cent of Amer­i­can men and 10–25 per­cent of women will suf­fer an episode of depres­sion, mak­ing it the most com­monly diag­nosed men­tal dis­or­der today. Unlike nor­mal sad­ness, which passes with time, depres­sion feels unstop­pable and causes peo­ple to lose inter­est in nearly all activ­i­ties. Because it affects a person’s abil­ity to eat, sleep, work, and func­tion nor­mally, it exacts a huge cost on the econ­omy, esti­mated at $30 bil­lion dol­lars annu­ally. The cost in human suf­fer­ing can­not be measured.

Mil­lions of peo­ple diag­nosed with depres­sion turn to med­ica­tion as a treat­ment, and many of the most pop­u­lar Read the rest of this entry »

We often talk about how stress man­age­ment is as impor­tant as cog­ni­tive train­ing for brain fit­ness. We have also seen how traders can improve their per­for­mance by learn­ing how to man­age emo­tions of anx­i­ety and fustration.

Golf Digest has just pub­lished an arti­cle on how golfers can see their game improved thanks to stress man­age­ment pro­grams. Golf Digest’s Edi­tion includes the arti­cle Play­ing with heart: Peb­ble Beach’s top teacher wants to choke­proof your game, explain­ing how Laird Small, direc­tor of the Peb­ble Beach Golf Acad­emy and the 2003 PGA of Amer­ica Teacher of the Year, has been using these pro­grams for a num­ber of years.

Even more inter­est­ingly, it also relates how Read the rest of this entry »