As the pres­i­dent and med­ical direc­tor of the Alzheimer’s Research and Pre­ven­tion Foun­da­tion (ARPF), it’s my job to stay on top of advances in the field of Alzheimer’s research. Recently, a num­ber of arti­cles in the med­ical lit­er­a­ture have caught my atten­tion. They are focused on a par­tic­u­lar ques­tion that con­cerns most Baby Boomers like me: “Is mem­ory loss just a nor­mal part of aging?” Read the rest of this entry »

Wel­come to Grand Rounds, the weekly col­lec­tion of best health and med­ical blog posts. This week we invite you to enjoy a broad range of insights, tips, and first-hand sto­ries, pre­sented as a Q&A con­ver­sa­tion with blog­gers will­ing to answer, below, a total of 22 good questions.

On Health and Med­i­cine

1. What can one-word pre­scrip­tions deliver
2. How does food pro­cess­ing change food´s nutri­tional value
3. Can diet Increases Risk of ADHD
4. Is alco­holism an illness
5. What´s bet­ter: steady dete­ri­o­ra­tion over 10 years, or symp­tom-free life for 9 years fol­lowed by rapid dete­ri­o­ra­tion in year 10

On Patient Life

1. As we talk about wellness…what about devel­op­ing self-compassion
2. Can patients with chronic pain still live a full life
3. What is the patient-doctor eti­quette for using Face­book and Twitter
4. Should patients in an ideal world con­tract directly with their doctors
5. What are patient advo­cates focus­ing on these days

On Health Care pro­fes­sion­als Read the rest of this entry »

As you have prob­a­bly seen, the Cog­ni­tive Health and Brain Fit­ness field is rapidly evolv­ing, so let me high­light some of the main recent devel­op­ments affect­ing the field:

1) Pub­lic pol­icy ini­tia­tives:
– The Gov­ern­ment of Ontario, Canada, announced a $10m invest­ment in Bay­crest Research Cen­ter to help develop and com­mer­cial­ize brain fit­ness tech­nolo­gies. This $10m invest­ment was matched with an addi­tional $10m by local investors.
– In the US, The Paul Well­stone and Pete Domenici Men­tal Health Par­ity and Addic­tion Equity Act of 2008 was signed into law, included in the recently-approved eco­nomic bailout bill. The pas­sage of this law has sig­nif­i­cant impli­ca­tions for health­care providers and tech­nol­ogy ven­dors alike.

2) Com­put­er­ized Cog­ni­tive Assess­ments Used by the US Mil­i­tary:
The US Army launched a new pol­icy requir­ing cog­ni­tive screen­ings of all sol­diers before deploy­ment (in order to bet­ter diag­nose poten­tial prob­lems such as PTSD and TBI upon return). ANAM was the selected com­put­er­ized bat­tery of tests.

3) Ven­ture & Angel Fundrais­ing for Cog­ni­tive Train­ing com­pa­nies:
A num­ber of devel­op­ers have raised money. Cog­niFit received $5m (from Milk Cap­i­tal), Lumos Labs $3m (First­Mark Cap­i­tal –pre­vi­ously called Pequot Ventures-, Nor­west Ven­ture Part­ners), Sci­en­tific Brain Train­ing $1.5m (issued shares), Viv­ity Labs $1m (undis­closed angel investors), This is, of course, on top of the Feb­ru­ary $10.6 invest­ment in Dakim (Galen Part­ners) that we already included in our mar­ket report.

4) Major Ini­tia­tives by Insur­ance Com­pa­nies:
– All­state launched a large-scale research project to mea­sure impact of Posit Sci­ence InSight (visual pro­cess­ing train­ing) on dri­ver safety for adults over 50.
– OptumHealth announced a 3-year, $18m agree­ment with Brain Resource to offer web-based cog­ni­tive assess­ments as part of clin­i­cians’ deci­sion sup­port sys­tems.
– Humana decided not to renew its agree­ment with Posit Sci­ence to offer Posit’s audi­tory pro­cess­ing train­ing pro­gram to Medicare members.

5) New Research:
– In a sig­nif­i­cant new study, a team from the Uni­ver­sity of Michi­gan pub­lished a high-quality paper in the Pro­ceed­ings of the National Acad­emy of Sci­ences show­ing how com­put­er­ized work­ing mem­ory train­ing can gen­er­al­ize and improve fluid intel­li­gence (one of the domains that tends to decline with age).
– Learn­ing and Teach­ing Scot­land released an inter­nal study show­ing how Nin­tendo Brain Train­ing can help children’s math and con­cen­tra­tion skills. The study gained sig­nif­i­cant media atten­tion, despite the fact it hasn’t been pub­lished in a respected journal.

Note: This is an excerpt from the 6-Month Mar­ket Update we will  release later this month, cov­er­ing the many impor­tant devel­op­ments that have occurred since we launched the inau­gural Brain Fit­ness Mar­ket Report in March this year. This spe­cial report will be avail­able exclu­sively for our Pre­mium Research Spon­sors.

You know your weight. And your phys­i­cal fit­ness. And a vari­ety of health-related metrics.

What about your brain fitness?

Two recent announce­ments bring out how the assess­ment of cog­ni­tive abil­i­ties, or brain func­tions, is increas­ingly being done thanks to new com­put­er­ized options:

1) Last week, OptumHealth announced an exclu­sive 3-year agree­ment (esti­mated at $18m) with the Aus­tralian com­pany Brain Resource. OptumHealth will be embed­ding the Brain Resource plat­form into their over­all Behav­ioral Solu­tions program.

- OptumHealth Behav­ioral Solu­tions will work with Brain Resource to pro­vide clin­i­cians with a Web-based assess­ment that mea­sures gen­eral cog­ni­tion (how peo­ple process infor­ma­tion) and social cog­ni­tion (how peo­ple man­age their emo­tions). This 40-minute assess­ment is based on well-known and val­i­dated tests of mem­ory, atten­tion, exec­u­tive func­tion, and response speed, and mood, social skills and emo­tional resilience.

Read the rest of this entry »

Round-up of inter­est­ing recent news on cog­ni­tive health and fit­ness: the field is in motion.

1) Bay­crest cre­ates Cen­tre for Brain Fit­ness with $10-million Invest­ment from Ontario Gov­ern­ment (Canada NewsWire)

2) Cog­ni­tive tests are the best way to select med­ical stu­dents (EurekAlert)

3) High blood pres­sure hard on the aging brain (Reuters)

4) Alzheimer’s tests ben­e­fi­cial for seniors (Atlanta-Journal Constitutional)

5) Dementia-Dreading Baby Boomers Spur Race to Invent Brain Games (Bloomberg)

6) Viv­ity Labs launches Fit Brains brain-training game site (VentureBeat) 

7) Depres­sion and Alzheimer’s (NHS Choices)

For selected quotes and com­ments, Read the rest of this entry »

I find via Mind­Hacks that NYT Mag­a­zine has pub­lished a great arti­cle titled The Gre­gar­i­ous Brain, sub­ti­tled “Williams syn­drome — a genetic acci­dent that causes cog­ni­tive deficits-”. The writer, David Dobbs, does an spec­tac­u­lar job at explain­ing that syn­drome in the con­text of what cog­ni­tive skills are and how they evolved. Some sam­ple quotes:

• “In the view of two of Bellugi’s fre­quent col­lab­o­ra­tors, Albert Gal­aburda, a Har­vard Med­ical School pro­fes­sor of neu­rol­ogy and neu­ro­science, and Allan Reiss, a neu­ro­sci­en­tist at the Stan­ford School of Med­i­cine, Nicki’s learned facil­ity at sports talk illus­trates a cen­tral les­son of Williams and, for that mat­ter, mod­ern genet­ics: genes (or their absence) do not hard-wire peo­ple for cer­tain behav­iors. There is no gene for under­stand­ing cal­cu­lus. But genes do shape behav­ior and per­son­al­ity, and they do so by cre­at­ing brain struc­tures and func­tions that favor cer­tain abil­i­ties and appetites more than others.”
• “…This doesn’t mean that spe­cific behav­iors are hard-wired. M.I.T. math majors aren’t born doing cal­cu­lus, and peo­ple with Williams don’t enter life telling sto­ries. As Allan Reiss put it: “It’s not just ‘genes make brain make behav­ior.’ You have envi­ron­ment and expe­ri­ence too. By envi­ron­ment, Reiss means less the atmos­phere of a home or a school than the end­less string of chal­lenges and oppor­tu­ni­ties that life presents any per­son start­ing at birth.”
• (Talk­ing about when our ances­tors started to live in larger groups) “But the big­ger groups imposed a new brain load: the mem­bers had to be smart enough to bal­ance their indi­vid­ual needs with those of the pack. This meant coop­er­at­ing and exer­cis­ing some indi­vid­ual restraint. It also required Read the rest of this entry »