Here you have the Novem­ber edi­tion of our monthly newslet­ter cov­er­ing cog­ni­tive health and brain fit­ness top­ics. Please remem­ber that you can sub­scribe to receive this Newslet­ter by email, using the box at the top of this page.

Liv­ing Well to 100

100 is the new 65: Why do some peo­ple live, and well, to 100? Researchers are try­ing to find out, reports Meera Lee Sethi at Greater Good Mag­a­zine. They are dis­cov­er­ing that genetic fac­tors may account for only 20 to 30 per­cent of a person’s lifes­pan, while envi­ron­men­tal and behav­ioral fac­tors can dic­tate the other 70 to 80 percent.

Does cof­fee boost cog­ni­tive func­tions over time? Dr. Pas­cale Mich­e­lon weighs the evi­dence and reports good and bad news. The good news: long-term effects seem more pos­i­tive than neg­a­tive, so cof­fee leads to no clear harm. The bad news: there are no clear ben­e­fi­cial effects on gen­eral brain func­tions (impli­ca­tion for pro­po­nents of “smart pills”: don’t use cof­fee as the analogy).

10 Inno­va­tions for the Aging Soci­ety: In the Thanksgiving’s spirit, we want to thank 10 pio­neers for emerg­ing inno­va­tions that may help mil­lions of peo­ple alive today to keep our brains in top shape per­haps till we are 100 or more. Many of those pio­neers will par­tic­i­pate in the inau­gural Sharp­Brains Sum­mit.

In Autopi­lot?

Train your autopilot.…and how to turn it off: Madeleine Van Hecke, Ph.D shares an excerpt from The Brain Advan­tage, in which she encour­ages main­tain­ing men­tal “autopi­lot” when it’s work­ing well, yet shift­ing to more con­scious delib­er­a­tions when needed.

Sci­en­tia Pro Pub­lica:  A good way to turn off autopi­lot is to enjoy some great sci­ence and nature blog­ging, cour­tesy of Sci­en­tia Pro Pub­lica blog car­ni­val. Addi­tion­ally, you can enjoy read­ing some of the best neu­ro­science, psy­chol­ogy and med­ical blog­ging at the first ever com­bined Grand Rounds/ Encephalon edi­tion.

Games for Health

Games for Health Research: The Robert Wood John­son Foun­da­tion announced more than $1.85 mil­lion in grants for research teams to study how dig­i­tal games can improve play­ers health. One of the grantees is UCSF’s Adam Gaz­za­ley (who will be speak­ing at the Sharp­Brains Sum­mit) to develop a dri­ving game for cog­ni­tive fit­ness among younger and older adults.

Smart industry-research col­lab­o­ra­tion: Lumos Labs and researchers Susanne Jaeggi and Mar­tin Buschkuehl announce a col­lab­o­ra­tion to make the orig­i­nal Dual N-Back work­ing mem­ory train­ing pro­gram avail­able online and use it for ongo­ing research.

News

Mar­ian C. Dia­mond to open Sharp­Brains Sum­mit: Kick­ing off our Jan­u­ary 2010 Sharp­Brains Sum­mit is Mar­ian C. Dia­mond, one of the pio­neers of neu­ro­plas­tic­ity research since the 1960s. She will intro­duce us to the human brain, its anatomy and func­tion, and impli­ca­tions of  neu­ro­plas­tic­ity for brain health and per­for­mance at any age.

The Sharp­Brains Guide’s reviews and inter­views: a col­lec­tion of links to inter­views and reviews of The Sharp­Brains Guide to Brain Fitness.

Net­work for Brain Fit­ness Inno­va­tion (members-only): Dis­cus­sion on the future of com­put­er­ized cog­ni­tive behav­ioral ther­apy; United BioSource acquires Cog­ni­tive Drug Research; inno­v­a­tive part­ner­ship between Nav­i­gen­ics and Posit Sci­ence; new research on brain impact of Tetris; how a drop in visual skills may pre­cede Alzheimer’s Dis­ease;  excel­lent report by the National Acad­e­mies for the US Army avail­able for free now.

Brain Teaser

Who will you believe, me or your own eyes? dis­cover the 3 Win­ners of the 2009 Best Visual Illu­sion of the Year Con­test. Neu­ro­sci­en­tists Susana Martinez-Conde and Stephen Mack­nik, who help orga­nize the con­test, will give a fun demo on Magic and the Brain at Sharp­Brains Sum­mit, to dis­cuss the lim­its of human per­cep­tion and cognition.

Enjoy the final month of 2009!

Press release: “Leader in cog­ni­tion mea­sure­ment inte­grates into UBC to max­i­mize mea­sure­ment pre­ci­sion of piv­otal end­points and ensure data integrity. United BioSource Cor­po­ra­tion (UBC) today announced the acqui­si­tion of CDR”

Press release (09/10/09): Here

Analy­sis for mem­bers of Sharp­Brains Net­work for Brain Fit­ness Inno­va­tion: Here

For con­text, see our pre­vi­ous arti­cle titled Com­put­er­ized Cog­ni­tive Assess­ments: oppor­tu­ni­ties and con­cerns, focused on the OptumHealth — Brain­Re­source part­ner­ship and inno­v­a­tive work by the US Army.

Here you have the August edi­tion of our monthly newslet­ter cov­er­ing cog­ni­tive health and brain fit­ness top­ics. Please remem­ber that you can sub­scribe to receive this Newslet­ter by email, using the box at the top of this page.

Sci­en­tific pub­li­ca­tion Fron­tiers in Neu­ro­science recently pub­lished a spe­cial issue on Aug­ment­ing Cog­ni­tion, and invited me to con­tribute with an arti­cle titled Prepar­ing Soci­ety for the Cog­ni­tive Age. Ground­break­ing brain research has occurred over the last 20 years. The oppor­tu­nity to improve brain health and per­for­mance is immense, but we need to ensure the mar­ket­place matures in a ratio­nal and sus­tain­able man­ner, both through health­care and non-healthcare chan­nels. Click Here to read my article.

Announce­ments

In May 2009 Sharp­Brains pub­lished The State of the Brain Fit­ness Soft­ware Mar­ket 2009, the main indus­try report for lead­ing orga­ni­za­tions prepar­ing their mem­bers, their clients, and their patients for the cog­ni­tive age. 150-pages long, the report includes a mar­ket sur­vey with 2,000+ respon­dents, detailed analy­sis of 20+ ven­dors, research briefs writ­ten by 12 lead­ing sci­en­tists and data and trends for 4 major cus­tomer segments.

Below we share the full Exec­u­tive Sum­mary of the report and announce an exclu­sive webi­nar on Sep­tem­ber 29th to dis­cuss the State of the Mar­ket in more depth with buy­ers of the report.

To order the report and access both the report and the webi­nar, you can click Here. (Only $975 –a 25% dis­count– using Dis­count Code Frontiers2009 before Sep­tem­ber 28th).

State of the Mar­ket

After many many months of men­tal stim­u­la­tion, phys­i­cal exer­cise and the cer­tain need for stress man­age­ment… we have just announced the release of the The State of the Brain Fit­ness Soft­ware Mar­ket 2009 report, our sec­ond annual com­pre­hen­sive mar­ket analy­sis of the US mar­ket for com­put­er­ized cog­ni­tive assess­ment and train­ing tools. In this report we esti­mate the size of the US brain fit­ness soft­ware mar­ket at $265M in 2008, up from $225M in 2007 (18% annual growth), and from $100m in 2005. Two seg­ments fuelled the mar­ket growth from 2007 to 2008: con­sumers (grew from $80m to $95m) and health­care & insur­ance providers (grew from $65m to $80m).

The 150-page report finds promis­ing research and ini­tia­tives to drive sig­nif­i­cant growth, com­bined with increased con­sumer con­fu­sion given aggres­sive mar­ket­ing claims and lack of edu­ca­tion and stan­dards. The report includes:
– The com­plete results of an exclu­sive Jan­u­ary 2009 Sur­vey with 2,000+ respon­dents
– A pro­pri­etary Mar­ket & Research Momen­tum Matrix to cat­e­go­rize 21 key ven­dors into four cat­e­gories
– 10 Research Exec­u­tive Briefs writ­ten by lead­ing sci­en­tists at promi­nent research labs
– An analy­sis of the level of clin­i­cal val­i­da­tion per prod­uct and cog­ni­tive domain

Top 10 High­lights from the report:

1) Con­sumers, seniors, com­mu­ni­ties and insur­ance providers drove year on year sus­tained growth, from $225m in 2007 to $265m in 2008. Rev­enues may reach between $1 bil­lion to $5 bil­lion by 2015, depend­ing on how impor­tant prob­lems (Pub­lic Aware­ness, Nav­i­gat­ing Claims, Research, Health Cul­ture, Lack of Assess­ment) are addressed.

2) Increased inter­est and con­fu­sion: 61% of respon­dents Strongly Agree with the state­ment Address­ing cog­ni­tive and brain health should be a health­care pri­or­ity. But, 65% Agree/Strongly Agree. I don’t really know what to expect from prod­ucts mak­ing brain claims.

3) Invest­ment in R&D seeds future growth: Land­mark invest­ments by insur­ance providers and government-funded research insti­tutes test­ing new brain fit­ness appli­ca­tions planted new seeds for future growth.

4) Becom­ing stan­dard in res­i­den­tial facil­i­ties: Over 700 res­i­den­tial facil­i­ties mostly Inde­pen­dent and Assisted Liv­ing facil­i­ties and CCRCs have installed com­put­er­ized cog­ni­tive train­ing programs.

5) Cus­tomer sat­is­fac­tion: Con­sumers seem more sat­is­fied with computer-based prod­ucts than paper-based options. But, sat­is­fac­tion dif­fers by prod­uct. When asked I got real value for my money, results were as fol­lows: Lumosity.com (65% Agree), Puz­zle Books (60%), Posit Sci­ence (52%), Nin­tendo (51%) agreed. Posit Sci­ence (53% Agree) and Lumosity.com (51%) do bet­ter than Puz­zle Books (39%) and Nin­tendo (38%) at I have seen the results I wanted.

6) Assess­ments: Increas­ing adop­tion of computer-based cog­ni­tive assess­ments to base­line and track cog­ni­tive func­tions over time in mil­i­tary, sports, and clin­i­cal con­texts. The Alzheimer’s Foun­da­tion of Amer­ica now advo­cates for wide­spread cog­ni­tive screen­ings after 65–75.

7) Spe­cific com­put­er­ized cog­ni­tive train­ing and videogames have been shown to improve brain func­tions, but the key ques­tions are, Which ones, and Who needs what when?

Aggres­sive mar­ket­ing claims are cre­at­ing con­fu­sion and skep­ti­cism, result­ing in a dis­tract­ing con­tro­versy between two mis­lead­ing extremes: (a) buy­ing prod­uct XYZ can reju­ve­nate your brain Y years or (b) those prod­ucts don’t work; just do one more cross­word puz­zle. The upcom­ing book The Sharp­Brains Guide to Brain Fit­ness aims to help con­sumers nav­i­gate these claims.

9) Devel­op­ers can be clas­si­fied into four groups, based on a pro­pri­etary Mar­ket and Research Momen­tum Matrix: Sharp­Brains finds 4 Lead­ers, 8 High Poten­tials, 3 Cross­words 2.0, and 6 Wait & See companies.

10) Increased dif­fer­en­ti­a­tion: Lead­ing com­pa­nies are bet­ter defin­ing their value propo­si­tion and dis­tri­b­u­tion chan­nels to reach spe­cific seg­ments such as retire­ment com­mu­ni­ties, schools, or health­care providers.

Lead­ing researchers pre­pared 10 Research Exec­u­tive Briefs:
- Dr. Joshua Stein­er­man (Einstein-Monteore): Neu­ro­pro­tec­tion via cog­ni­tive activ­i­ties
– Dr. Jerri Edwards (South Florida): Assess­ments of dri­ving fit­ness
– Dr. Susanne Jaeggi and Dr. Mar­tin Buschkuehl (Bern, Michi­gan): Work­ing mem­ory train­ing and  intel­li­gence
– Dr. Torkel Kling­berg (Karolin­ska): Work­ing mem­ory train­ing, dopamine, and math
– Dr. Liz Zelin­ski (UC Davis): Audi­tory pro­cess­ing train­ing
– Dr. David Vance (UAB): Speed-of-processing train­ing
– Dr. Jerri Edwards (South Florida): Cog­ni­tive train­ing for healthy aging
– Dr. Daphne Bave­lier & Dr. Shawn Green (Rochester): Action videogames and atten­tional skills
– Dr. Arthur Kramer (Illi­nois): Strat­egy videogames and exec­u­tive func­tions
– Dr. Yaakov Stern (Colum­bia): The cog­ni­tive reserve and neu­roimag­ing
– Dr. David Rabiner (Duke): Objec­tive assess­ments for ADHD

Table of Contents

Edi­to­r­ial
Exec­u­tive Sum­mary
Chap­ter 1. Bird-Eye View of the Grow­ing Field
Chap­ter 2. Mar­ket Sur­vey on Beliefs, Atti­tudes, Pur­chase Habits
Chap­ter 3. The Emerg­ing Com­pet­i­tive Land­scape
Chap­ter 4. The Sci­ence for Brain Fit­ness and Cog­ni­tive Health
Chap­ter 5. Con­sumers  Adopt­ing Cross­words 2.0?
Chap­ter 6: Health­care and Insur­ance Providers — A Cul­ture of Cog­ni­tive Health
Chap­ter 7: K12 School Sys­tems– Ready for Change?
Chap­ter 8: Mil­i­tary, Sports Teams, Com­pa­nies,  Brain-Performance Link
Chap­ter 9: Future Direc­tions‚ Pro­jec­tions and Bottlenecks

Com­pa­nies pro­filed include: Advanced Brain Tech­nolo­gies, Applied Cog­ni­tive Engi­neer­ing, Brain Cen­ter Amer­ica, Brain Resource, CNS Vital Signs, Cogmed, Cogstate, Cog­niFit, Cog­ni­tive Drug Research, Dakim, Houghton Mif­flin, Learn­ing Enhance­ment Cor­po­ra­tion, Learn­ingRx, Lumos Labs, Mar­bles: The Brain Store, Nin­tendo, NovaV­i­sion, Posit Sci­ence, Sci­en­tific Brain Train­ing, Sci­en­tific Learn­ing, Trans­An­a­lyt­ics, vibrant­Brains, Vig­or­ous Mind, Viv­ity Labs.

More on the report by click­ing on The State of the Brain Fit­ness Soft­ware Mar­ket 2009.

Just saw a very inter­est­ing press release regard­ing computer-based neu­rocog­ni­tive assess­ments — a crit­i­cal part of the brain fit­ness puz­zle. How long will it take before con­sumers can have access to a reli­able and cred­i­ble annual “men­tal check-up”/ cog­ni­tive baseline?

Head­Min­der Cog­ni­tive Sta­bil­ity Index: Com­put­er­ized Neu­rocog­ni­tive … (Press release)

- “The Head­Min­der web-based Cog­ni­tive Sta­bil­ity Index (CSI) has proven more use­ful for blast-concussion detec­tion than the ANAM com­put­er­ized test bat­tery the DoD cur­rently employs. The CSI pro­vides an imme­di­ate solu­tion to clear the back­log of 400,000 IED-exposed ser­vice mem­bers in less than two years.”

- “The CSI is a 30-minute, Internet-based, com­put­er­ized test that pro­vides auto­mated, objec­tive mea­sures of atten­tion, mem­ory, response speed, and pro­cess­ing speed for ini­tial eval­u­a­tion of cog­ni­tive func­tion­ing. The CSI pro­duces stan­dard­ized reports that enable triage and decision-making appro­pri­ate to a user’s qual­i­fi­ca­tions — from medic to neu­ropsy­chol­o­gist to neu­rol­o­gist and other treat­ment team members.”

We cov­ered this emerg­ing type of assess­ments in the arti­cle Com­put­er­ized Cog­ni­tive Assess­ments: oppor­tu­ni­ties and concerns

- “In fact, one of the Read the rest of this entry »

Over the next weeks we are going to be shar­ing the Exec­u­tive Sum­mary of our mar­ket report The State of the Brain Fit­ness Soft­ware Mar­ket 2008 with mem­bers and clients of sev­eral part­ner orga­ni­za­tions (the British Colum­bia Seniors Liv­ing Asso­ci­a­tion, where I will be speak­ing this Thurs­day, Neu­rotech Reports, where I will speak on Octo­ber 24th, and the Health 2.0 con­fer­ence, where we are spon­sor­ing a panel on gam­ing for health), so it is only fair that we first share it with our own readers.

Exec­u­tive Summary

A spate of recent global news cov­er­age on brain fit­ness and brain train­ing reflects a grow­ing inter­est in nat­ural, non drug-based inter­ven­tions to keep our brains sharp as we age. This inter­est is very timely, given an aging pop­u­la­tion, increas­ing preva­lence of Alzheimer’s rates, and soar­ing health care costs in the US that place more empha­sis than ever on pre­ven­tion and lifestyle changes.

US brain fit­ness mar­ket: sig­nif­i­cant and growing

We esti­mate the size of the US brain fit­ness mar­ket was $225m in 2007 – more than dou­ble what it was in 2005. Whereas K12 school sys­tems were the largest buy­ers in 2005, con­sumers were respon­si­ble for most of the growth from 2005 to 2007. We esti­mate that the con­sumer seg­ment grew from a few mil­lion in 2005 to $80m in 2007, and fore­see sig­nif­i­cant mar­ket growth dri­ven not only by con­sumers but also by health­care and insur­ance providers.

Mar­ket dynamics

As we speak to diverse audi­ences about this emerg­ing field around the coun­try we are fre­quently asked the fol­low­ing questions:

- Why are we talk­ing about the brain fit­ness field at all?

Over the past decade, teams backed by neu­ro­sci­en­tists around the world Read the rest of this entry »

You know your weight. And your phys­i­cal fit­ness. And a vari­ety of health-related metrics.

What about your brain fitness?

Two recent announce­ments bring out how the assess­ment of cog­ni­tive abil­i­ties, or brain func­tions, is increas­ingly being done thanks to new com­put­er­ized options:

1) Last week, OptumHealth announced an exclu­sive 3-year agree­ment (esti­mated at $18m) with the Aus­tralian com­pany Brain Resource. OptumHealth will be embed­ding the Brain Resource plat­form into their over­all Behav­ioral Solu­tions program.

- OptumHealth Behav­ioral Solu­tions will work with Brain Resource to pro­vide clin­i­cians with a Web-based assess­ment that mea­sures gen­eral cog­ni­tion (how peo­ple process infor­ma­tion) and social cog­ni­tion (how peo­ple man­age their emo­tions). This 40-minute assess­ment is based on well-known and val­i­dated tests of mem­ory, atten­tion, exec­u­tive func­tion, and response speed, and mood, social skills and emo­tional resilience.

Read the rest of this entry »

A few col­leagues referred me over the week­end to a very nice arti­cle at busi­ness pub­li­ca­tion Port­fo­lio.

While the arti­cle does an excel­lent job at intro­duc­ing the reader to the con­cept and promise of com­put­er­ized cog­ni­tive assess­ments, it also con­tributes to the mythol­ogy of “Brain Age”.

Let’s first take a look at the arti­cle How Smart Are You: The busi­ness of assess­ing cog­ni­tion and mem­ory is mov­ing from test­ing brain-impaired patients to assess­ing healthy peo­ples’ brains online.

A cou­ple of quotes:

- “Cog­ni­tive Drug Research is one a hand­ful of busi­nesses, most of them out­side of the U.S., that work with phar­ma­ceu­ti­cal com­pa­nies to test how new drugs for every­thing from nico­tine addic­tion to Alzheimer’s dis­ease affect the mind’s abil­ity to remem­ber things, make deci­sions, and ana­lyze information.”

- “Cog­ni­tive tests have been around for a cen­tury as exam­i­na­tions taken with paper and pen­cil. In the 1970s and ‘80s the tests shifted to com­put­ers, Cog­ni­tive Drug Research founder Keith Wesnes says.

So far, so good. In fact, one of the key high­lights from the mar­ket report we released in March was that “Large-scale, fully-automated cog­ni­tive assess­ments are being used in a grow­ing num­ber of clin­i­cal tri­als. This opens the way for the devel­op­ment of inex­pen­sive consumer-facing, base­line cog­ni­tive assess­ments.” And we pro­filed a few lead­ing com­pa­nies in the space: Brain Resource Com­pany, Cog­ni­tive Drug Research, CNS Vital Signs and CogState.

Now, the arti­cle is accom­pa­nied by a 5–7 minute quick test that promises to give us our “Brain Age”. And this doesn’t come from Nin­tendo, but from Cog­ni­tive Drug Research, a respected science-based company.

You can check it out Read the rest of this entry »

Grow­ing media atten­tion on the brain fit­ness field. At least on the “Healthy Aging” seg­ment (I pre­dict the media with catch up soon with devel­op­ments in other areas, from cog­ni­tive train­ing for kids and adults with ADD/ ADHD to stroke and TBI reha­bil­i­ta­tion, to peak per­for­mance for cor­po­rate training).

First, a superb arti­cle by Leslie Walker at the Wash­ing­ton Post: Cross-Training Your Brain to Main­tain Its Strength

Quotes:  “A grow­ing body of research sug­gests that men­tal activ­ity in mid­dle age and ear­lier can help later in life. As a result, Web sites such as HappyNeuron.com are spring­ing up to offer online games to peo­ple of all ages, while blogs like SharpBrains.com pro­vide com­men­tary on the fledg­ling indus­try.” (Note: we can also pro­vide com­men­tary on the commentary!)

“Peo­ple who engage in very chal­leng­ing tasks — not just in work but dur­ing leisure activ­i­ties such as read­ing, cross­word puz­zles, bridge, chess and travel — tend to slow down their men­tal aging process very sig­nif­i­cantly,” says Breznitz, who is also a mem­ber of Israel’s leg­is­la­ture and has devel­oped a brain-training pro­gram called MindFit.”

“Also con­tribut­ing to the brain work­out boom are state-of-the-art imag­ing tech­niques that have allowed sci­en­tists to val­i­date a the­ory devel­oped decades ago. By tak­ing detailed pic­tures of brain neu­rons, sci­en­tists watch parts of the brain that had seemed dor­mant light up and assume new respon­si­bil­i­ties in response to stim­uli. The­o­ret­i­cally, this means brain decay can be halted or even reversed.”

“The brain is con­stantly rewiring and recal­i­brat­ing itself in response to what you do,” says Henry Mah­ncke, who holds a PhD in neu­ro­science and is vice pres­i­dent of Posit Sci­ence, the San Fran­cisco devel­oper of the Brain Fit­ness soft­ware. “It remakes itself into a more effi­cient oper­a­tion to do the things you ask it to do.”

Com­ments: the arti­cle touches many key points. I espe­cially enjoy the quote “To be effec­tive, sci­en­tists say men­tal activ­ity must become pro­gres­sively more chal­leng­ing. Oth­er­wise, the brain adjusts and learns to per­form repet­i­tive tasks with less effort”, a key mes­sage I make often in my lec­tures to explain why well-designed pro­grams can be more effec­tive than doing cross­word puz­zle num­ber 512,789. The arti­cle also relates how many retire­ment com­mu­ni­ties and senior cen­ters and indi­vid­u­als are try­ing out the new brain fit­ness pro­grams com­ing to mar­ket, and shows some healthy skep­ti­cism on the state of the research. Now, this is an invi­ta­tion to the reporter to inter­view neu­ropsy­chol­o­gist Dr. Elkhonon Gold­berg to get the full pic­ture of the sci­ence behind the field, since these pro­grams haven’t appeared in a vac­uum. Our 10-Question Eval­u­a­tion Check­list can pro­vide use­ful guid­ance to any­one con­sid­er­ing a program.

Boomers use online brain games to stave off demen­tia (AccountingWeb)

Quotes: “The Inter­net offers a plethora of brain games for those who don’t sub­scribe to a daily news­pa­per or don’t want to pur­chase games. AARP, for exam­ple, offers plenty of free games on its site. More games appear at SharpBrains.com, includ­ing a page that con­tains the Top Ten Neu­ro­science Brain­teasers, and you can sign up to have the Col­lege Board e-mail you the SAT ques­tion of the day.”

“The gen­er­a­tion that refuses to age is not going to sit back and wait for Alzheimer’s Dis­ease and other signs of demen­tia to take hold. Instead, savvy Baby Boomers are expand­ing their minds (no, not the way they did in the 60s) with the aid of the com­puter, puz­zles, and games. A brain health move­ment is sweep­ing Read the rest of this entry »