I wanted to alert you to a very inter­est­ing find­ing pub­lished in a recent issue of Sci­ence, one of the world’s lead­ing sci­en­tific journals.

The study was led by Dr. Torkel Kling­berg and his col­leagues from the Karolin­ska Insti­tute in Swe­den. The goal was to learn whether Work­ing Mem­ory Train­ing is asso­ci­ated with changes in brain bio­chem­istry, thus sug­gest­ing a mech­a­nism by which train­ing may lead to enhanced work­ing mem­ory capac­ity and a reduc­tion in atten­tion prob­lems. Thus, although Work­ing Mem­ory Train­ing has pre­vi­ously shown promis­ing results as a treat­ment for work­ing mem­ory and atten­tion dif­fi­cul­ties, this was a basic sci­ence study rather than a treat­ment study.

The major find­ing was that increased work­ing mem­ory capac­ity fol­low­ing train­ing was asso­ci­ated with changes in brain bio­chem­istry. Specif­i­cally, the researchers found changes in the den­sity and bind­ing poten­tial of cor­ti­cal D1 dopamine recep­tors in brain regions that are acti­vated dur­ing work­ing mem­ory tasks.

Results from this study sug­gest a bio­log­i­cal basis for the improve­ment in work­ing mem­ory capac­ity and reduc­tions i Read the rest of this entry »

Cog­ni­tive Train­ing Can Alter Bio­chem­istry Of The Brain (Sci­ence Daily)

- “Researchers at the Swedish med­ical uni­ver­sity Karolin­ska Insti­tute have shown for the first time that the active train­ing of the work­ing mem­ory brings about vis­i­ble changes in the num­ber of dopamine recep­tors in the human brain.”

- ““Brain bio­chem­istry doesn’t just under­pin our men­tal activ­ity; our men­tal activ­ity and think­ing process can also affect the bio­chem­istry,” says Pro­fes­sor Torkel Kling­berg, who led the study.”

- “Changes in the num­ber of dopamine recep­tors in a per­son doesn’t give us the key to poor mem­ory,” says Pro­fes­sor Lars Farde, one of the researchers who took part in the study. “We also have to ask if the dif­fer­ences could have been caused by a lack of mem­ory train­ing or other envi­ron­men­tal fac­tors. Maybe we’ll be able to find new, more effec­tive treat­ments that com­bine med­ica­tion and cog­ni­tive train­ing, in which case we’re in extremely inter­est­ing territory.”

Com­ment:  couldn’t agree more with “Maybe we’ll be able to find new, more effec­tive treat­ments that com­bine med­ica­tion and cog­ni­tive train­ing, in which case we’re in extremely inter­est­ing ter­ri­tory.” This study adds a very impor­tant angle to the grow­ing lit­er­a­ture on work­ing mem­ory train­ing, show­ing a more fun­da­men­tal, struc­tural impact, that once thought (such as the well-known effect that “cells that fire together wire together”). The com­put­er­ized cog­ni­tive pro­gram used in the study was Cogmed work­ing mem­ory training.

More on Torkel Klingberg’s research:

- Arti­cle writ­ten by Torkel Kling­berg on The Over­flow­ing Brain & Infor­ma­tion Overload

- His recent book, which was The Sharp­Brains Most Impor­tant Book of 2008: The Over­flow­ing Brain: Infor­ma­tion Over­load and the Lim­its of Work­ing Memory

- 2006 Inter­view with Dr. Kling­berg: Work­ing Mem­ory Train­ing and RoboMemo: Inter­view with Dr. Torkel Klingberg

Quick links to excel­lent resources:

1) FEATURE-Brain fit­ness seen as hot indus­try of the future (Reuters)

2) Learn­ing & the Brain Con­fer­ence for Edu­ca­tors and Clin­i­cians. April 26–29, 2008. Cam­bridge, MA

3) Brain Health Across the Lifes­pan Sem­i­nar for Health & Aging Pro­fes­sion­als. May 15th, 2008. San Fran­cisco, CA

For more info, Read the rest of this entry »

If you want to live long and strong, you’ve got to do more than work out your body; you’ve got to exer­cise your brain, insists Dr. Elkhonon Gold­berg, clin­i­cal pro­fes­sor of neu­rol­ogy at New York Uni­ver­sity School of Med­i­cine. While we’ve heard for years that men­tal stim­u­la­tion can stave off demen­tia and Alzheimer’s, Dr. Gold­berg says sci­en­tists now know exactly how to keep our brains from turn­ing to mush – by stim­u­lat­ing the growth of new neu­rons and inter­con­nec­tions between them that boost brain effi­ciency. If you don’t use your brain in new and novel ways, your brain won’t be fit to use.

As the chief sci­en­tific adviser for SharpBrains.com, Dr. Goldberg’s site offers an array of brain teasers and exer­cises that improve brain func­tion. But online tests are not all you can do. Just do some­thing dif­fer­ent and chal­leng­ing. Get­ting out of your middle-aged com­fort zone is the dif­fer­ence in a high qual­ity of life when you’re older than none at all.

Keep read­ing more of the Florida Today inter­view with Dr. Gold­berg at Next Up, A Gym for the Mind.

You can also read our more detailed (and prob­a­bly more pre­cise) inter­view with Dr. Elkhonon Gold­berg on Brain Fit­ness and Cog­ni­tive Train­ing.