Very sig­nif­i­cant find­ings reported today. Keep­ing brain sharp may ward off Alzheimer’s pro­tein (Reuters):

“Peo­ple who chal­lenge their brains through­out their life­times — through read­ing, writ­ing and play­ing games — are less likely to develop pro­tein deposits in the brain linked with Alzheimer’s, researchers said on Mon­day.” Read the rest of this entry »

Below you can find the full tran­script of our engag­ing Q&A ses­sion yes­ter­day on holis­tic brain health with clin­i­cal neu­ropsy­chol­o­gist Dr. Paul Nuss­baum, author of Save Your Brain. You can learn more about the full Brain Fit­ness Q&A Series Here.

Per­haps one of the best exchanges was: Read the rest of this entry »

Wel­come to the XL edi­tion of Sci­en­tia Pro Pub­lica (or, since we are try­ing to speak Eng­lish, the 40th edi­tion of “Sci­ence for the Peo­ple”), the rotat­ing blog car­ni­val that show­cases the finest sci­ence, med­ical and envi­ron­ment writ­ing pub­lished in the blogosphere.

Quick now — ask a ques­tion, any ques­tion, that comes to mind. Chances are some­one in this excel­lent ros­ter of sci­ence blog­gers has antic­i­pated it and pro­vided an answer below. Enjoy!

About our­selves

1. Why do I feel bet­ter after I exer­cise (pic: brainblogger)
2. Can thought­ful blog­ging and read­ing build brain reserve and delay dementia
3. What’s the bor­der­line between high and low func­tion­ing — autism research examples
4. Can we learn to multi-task more effectively
5. Should you mind your brain

About our bod­ies Read the rest of this entry »

Here you have the Sep­tem­ber edi­tion of our monthly newslet­ter cov­er­ing cog­ni­tive health and brain fit­ness top­ics. Please remem­ber that you can sub­scribe to receive this Newslet­ter by email, using the box at the top of this page.

In the cur­rent edi­tion of The Jour­nal on Active Aging, I dis­cuss why we need to Retool “Use it or lose it”, and why rou­tine, doing things inside our com­fort zones, is the most com­mon enemy of the nov­elty, vari­ety and chal­lenge our brains need. You can read the full arti­cle for free Here.

Book Tour

We are glad to report that The Sharp­Brains Guide to Brain Fit­ness con­tin­ues to obtain excel­lent endorsements:

“This is the only book that I know of that seam­lessly inte­grates lat­est infor­ma­tion about cog­ni­tive health across the lifes­pan. Very use­ful to any­one inter­ested in brain care.”

–Arthur Kramer, Ph. D., Pro­fes­sor of Psy­chol­ogy at Uni­ver­sity of Illinois

“…we now have a rock solid primer on brain health that we can rec­om­mend with confidence…I found it par­tic­u­larly effec­tive to start the book with a list of ten brain myths that need debunk­ing.“
–Michael C. Pat­ter­son, for­mer Man­ager NRTA/ Stay­ing Sharp at AARP

The offi­cial book tour starts this week, and includes New York Pub­lic Library!
09/08: Club One Fit­ness Cen­ter, Petaluma, CA
09/09: San Fran­cisco State Uni­ver­sity OLLI
09/11: ASA Brain Health Day, Oak­land, CA
09/23: New York Pub­lic Library, Bronx Library Cen­ter
09/25: New York Pub­lic Library, Stephen Schwarz­man Build­ing
10/06, Smart­Sil­vers MIT North­ern Cal­i­for­nia, Palo Alto, CA
10/14: UC-Berkeley OLLI, CA

You can find all the details here. If you haven’t read the book yet, you can order it via Ama­zon Here (print book) or Here (Kin­dle edi­tion). Or ask your local book­store or library.

Brain Reserve

Given the grow­ing media cov­er­age men­tion­ing the terms Cog­ni­tive Reserve and Brain Reserve, you may be ask­ing your­self, “What exactly is my Cog­ni­tive (or Brain) Reserve?”

The cog­ni­tive reserve hypoth­e­sis, tested in mul­ti­ple stud­ies, states that indi­vid­u­als with more cog­ni­tive reserve can expe­ri­ence more Alzheimer’s dis­ease pathol­ogy in the brain (more plaques and tan­gles) with­out devel­op­ing Alzheimer’s dis­ease symptoms.

How does that work? Sci­en­tists are not sure but two pos­si­bil­i­ties are con­sid­ered.
1. One is that more cog­ni­tive reserve means more brain reserve, that is more neu­rons and con­nec­tions (synapses) between neu­rons. Indi­vid­u­als with more synapses would then have more synapses to lose before the crit­i­cal thresh­old for Alzheimer’s Dis­ease is reached.
2. Another pos­si­bil­ity is that more cog­ni­tive reserve means more com­pen­satory processes. The brain of indi­vid­u­als with more cog­ni­tive reserve would use more alter­na­tive net­works to com­pen­sate for the dam­ages caused by the pathol­ogy in pre­vi­ously used networks.

In a newly pub­lished study, Roe and col­leagues from Wash­ing­ton Uni­ver­sity in St. Louis, used the num­ber of years of edu­ca­tion as a mea­sure of cog­ni­tive reserve. Why years of edu­ca­tion? Because pre­vi­ous stud­ies have shown that peo­ple who have more edu­ca­tion also exhibit a greater resis­tance to Alzheimer’s symp­toms, even while patho­log­i­cal changes are occur­ring in the brain (see Ben­nett el al., 2003 or Roe, Xiong, et al., 2008).

Roe and her col­leagues stud­ied 198 indi­vid­u­als whose mean age was 67. Out of these 198 indi­vid­u­als, 161 were non­de­mented and 37 were diag­nosed with Alzheimer’s Disease.

All the par­tic­i­pants in the study took a Read the rest of this entry »

As men­tioned before, the World Eco­nomic Forum asked me to write “an 800 words sum­mary of your most com­pelling action­able idea on the chal­lenges of geron­tol­ogy”, in prepa­ra­tion for the Inau­gural Sum­mit of the Global Agenda that will take place Novem­ber 7 to 9th in Dubai.A good num­ber of Sharp­Brains read­ers and clients offered their insights — and expressed an inter­est in read­ing the draft. So below you have — a pro­posal to cre­ate a Global Con­sor­tium for Neu­rocog­ni­tive Fit­ness Inno­va­tion, build­ing on our exist­ing mar­ket research and advi­sory ser­vices work. Your thoughts?

—–

The Con­text

Grow­ing Demands on Our Brains: Pic­ture 6.7 bil­lion Prim­i­tive Brains inhab­it­ing a Knowl­edge Soci­ety where life­long learn­ing and mas­ter­ing con­stant change in com­plex envi­ron­ments are crit­i­cal for pro­duc­tive work, health and per­sonal fulfillment.

Wel­come to Planet Earth, 2008.

Fur­ther stretched by increased longevity: Now pic­ture close to 1 bil­lion of those brains over the age of 60 – and please remem­ber that, less than 100 years ago, life expectancy was between 30 to 40 years. The rapidly evolv­ing Knowl­edge Soci­ety is plac­ing new and enor­mous demands on our “prim­i­tive” human brains. And the longer our lifes­pans, the more obvi­ous the “cog­ni­tive gap”. Hence, from a health point of view, the grow­ing Read the rest of this entry »

A cou­ple of recent research find­ings are mak­ing the media rounds, bring­ing much needed atten­tion to the high Alzheimer’s rates among Lati­nos and to pre­ven­tive approaches based on the Cog­ni­tive Reserve — such as, what jobs we choose:

More Alzheimer’s risk for His­pan­ics, stud­ies find (Inter­na­tional Her­ald Tribune):

- Stud­ies sug­gest that many His­pan­ics may have more risk fac­tors for devel­op­ing demen­tia than other groups, and a sig­nif­i­cant num­ber appear to be get­ting Alzheimer’s ear­lier. And sur­veys indi­cate that Lati­nos, less likely to see doc­tors because of finan­cial and lan­guage bar­ri­ers, more often mis­take demen­tia symp­toms for nor­mal aging, delay­ing diagnosis.

- “This is the tip of the ice­berg of a huge pub­lic health chal­lenge,” said Yanira Cruz, pres­i­dent of the National His­panic Coun­cil on Aging. “We really need to Read the rest of this entry »

We just received this quote of how a major health sys­tem is using our Brain Fit­ness Mar­ket Report:

“At Sut­ter Health Part­ners we rec­og­nize the impor­tance of brain health and how much the health of the brain and the body are inter­de­pen­dent.  The mar­ket report helped us fur­ther tar­get our coach­ing efforts to inte­grate brain fit­ness and upgrade our entire coach­ing plat­form.  It is easy to read and gives you the indus­try per­spec­tive in a thor­ough yet con­cise man­ner.  I highly rec­om­mend it!”

– Mar­garet Sabin, CEO of Sut­ter Health Part­ners and VP, New Prod­uct Devel­op­ment, at Sut­ter Health.

You may won­der, “what is the link between  well­ness coach­ing and brain fitness”?

In prac­tice, good health and well­ness coaches pro­vide excel­lent brain health advice, given that the areas they focus on (nutri­tion, phys­i­cal exer­cise, stress man­age­ment) do play an impor­tant role in main­tain­ing our brains in top shape.

Addi­tion­ally, pio­neers  such as Sut­ter Health Part­ners are adding a Brain “lens” to their work. How?

First, by bet­ter under­stand­ing and explain­ing the brain ben­e­fits of what they already do, in order to pro­vide addi­tional moti­va­tion to stick with healthy behav­iors. For exam­ple, most peo­ple will be able to recite mul­ti­ple ben­e­fits of mod­er­ate car­dio­vas­cu­lar exer­cise. But how many know  that it can also con­tribute to neu­ro­ge­n­e­sis –the cre­ation of new neu­rons — in adult brains?

Sec­ond, by start­ing to offer brain fit­ness guide­lines to clients who want too go beyond cross­word puz­zles and sudoku.

I had a great train­ing ses­sion with a num­ber of Sut­ter Health coaches last week — let me sum­ma­rize some of the main points we cov­ered. Read the rest of this entry »

Wel­come to the third edi­tion of Hour­glass, the monthly vir­tual gath­er­ing of blog­gers to dis­cuss the Biol­ogy of Aging.

For today’s edi­tion, let’s imag­ine all par­tic­i­pants sit­ting around a table lead­ing a lively Ques­tions & Answers ses­sion, dis­cussing as a group, lis­ten­ing, talk­ing. (And, well, aging.)

Q: What is aging?
Ms. Wikipedia: “Age­ing or aging (Amer­i­can Eng­lish) is the accu­mu­la­tion of changes in an organ­ism or object over time. Age­ing in humans refers to a mul­ti­di­men­sional process of phys­i­cal, psy­cho­log­i­cal, and social change. Some dimen­sions of age­ing grow and expand over time, while oth­ers decline. Reac­tion time, for exam­ple, may slow with age, while knowl­edge of world events and wis­dom may expand.”

Aging may not be the sex­i­est  of words in our vocab­u­lary. Unless, of course (as I heard some­where recently but can’t prop­erly credit), you con­sider the most com­mon alternative.

Q: If the objec­tive of anti-aging research is to extend lifes­pan, isn’t there a risk that we may neglect qual­ity of life. After all, would peo­ple really like to spend more years afflicted by the dis­eases and the decline that often come with age?
Ed (dragged to the dis­cus­sion by Chris and Alvaro): I have rel­a­tively good news to share. A recent Uni­ver­sity of South­ern Den­mark found that the pro­por­tion of elderly Danes who man­age to remain inde­pen­dent holds steady at Read the rest of this entry »

We had a very fun ses­sion titled Teach­ing Brain Fit­ness in Your Com­mu­nity at an Amer­i­can Soci­ety on Aging (ASA) con­fer­ence for health pro­fes­sion­als a cou­ple of weeks ago. Full house, with over 60 atten­dants and very good par­tic­i­pa­tion, show­ing great inter­est in the topic. I can’t wait to see the evaluations.

These are some of the resources I promised as a follow-up, which can be use­ful to every­one inter­ested in our field:

Good gen­eral arti­cles in the busi­ness and gen­eral media:

Change or Die

Want a sharp mind for your golden years? Start now

You’re Wiser Now

On how new neu­rons are born and grow in the adult brain:

Salk Sci­en­tists Demon­strate For The First Time That Newly Born Brain Cells Are Func­tional In The Adult Brain

Old Brains, New Tricks

On the sur­pris­ing plas­tic­ity and devel­op­ment poten­tial through­out life:

Brain Plas­tic­ity, Lan­guage Pro­cess­ing and Reading

Jug­gling Jug­gles the Brain

Suc­cess­ful Aging of the Healthy Brain

Other impor­tant aspects:

Stress and the Brain

Exer­cise and the Brain

Humor, Laugh­ter and The Brain

On the impor­tance and impact of men­tal stim­u­la­tion and train­ing: Read the rest of this entry »