Below you can find the full tran­script of our engag­ing Q&A ses­sion yes­ter­day on holis­tic brain health with clin­i­cal neu­ropsy­chol­o­gist Dr. Paul Nuss­baum, author of Save Your Brain. You can learn more about the full Brain Fit­ness Q&A Series Here.

Per­haps one of the best exchanges was: Read the rest of this entry »

(Editor’s note: below you have the final part of the 6-part Stress and the Brain series. If you are join­ing the series now, you can read the pre­vi­ous parts via the links below.)

Stayin’ Alive

TO FIGHT, FLEE, OR FREEZE — THAT IS THE QUESTION

With a bet­ter under­stand­ing of the neu­ro­bi­ol­ogy of stress, the LD — ADHD — stress con­nec­tion becomes clear.  Stu­dents with learn­ing dis­abil­i­ties or ADHD, con­fronted with the stress cre­ated by expo­sure to tasks that are in real­ity or in their per­cep­tion too dif­fi­cult (and thus threat­en­ing), exhibit the pro­tec­tive behav­ior of any organ­ism under extreme stress:  They fight, they flee, or they freeze. When these kids don’t under­stand why they can’t do what other kids can do (mas­ter the stres­sor), and they can’t see any way to get out of a sit­u­a­tion that won’t go away, they begin to shut down. Read the rest of this entry »

(Editor’s note: below you have part 5 of the 6-part The Neu­ro­bi­ol­ogy of Stress series. If you are join­ing the series now, you can read the pre­vi­ous part Here.)

Stayin’ Alive

The Human Brain Likes to Be in Balance

For­tu­nately, the brain has some built — in safety sys­tems. Too much cor­ti­sol in the blood sig­nals the brain and adrenal glands to decrease cor­ti­sol pro­duc­tion. And under nor­mal con­di­tions, when the stress is over­come or brought under con­trol (by fight­ing, flee­ing, or turn­ing into an immo­bile statue, or by mas­ter­ing the threat), the hypo­thal­a­mus starts send­ing out the orders to stand down. Stop pro­duc­ing cor­ti­sol!  Event over!  Under con­tin­u­ous stress, how­ever, this feed­back sys­tem breaks down. The hypo­thal­a­mus keeps read­ing the stress as a threat, furtively send­ing mes­sages to the pitu­itary gland, which screams out to the adrenal glands to keep pump­ing out cor­ti­sol, which at this point begins to be neu­ro­toxic — poi­son to the brain. Read the rest of this entry »

(Editor’s note: below you have part 4 of the 6-part The Neu­ro­bi­ol­ogy of Stress series. If you are join­ing the series now, you can read the pre­vi­ous part Here.)

Stayin’  Alive

THE STRESS RESPONSE EXPLAINED

Stress was put on the map, so to speak, by a Hun­gar­ian — born Cana­dian endocri­nol­o­gist named Hans Hugo Bruno Selye (ZEL — yeh) in 1950, when he pre­sented his research on rats at the annual con­ven­tion of the Amer­i­can Psy­cho­log­i­cal Asso­ci­a­tion. To explain the impact of stress, Selye pro­posed some­thing he called the Gen­eral Adap­ta­tion Syn­drome (GAS), which he said had three com­po­nents. Accord­ing to Selye, when an organ­ism expe­ri­ences some novel or threat­en­ing stim­u­lus it responds with an alarm reac­tion. This is fol­lowed by what Selye referred to as the recov­ery or resis­tance stage, a period of time dur­ing which the brain repairs itself and stores the energy it will need to deal with the next stress­ful event.

Read the rest of this entry »

(Editor’s note: below you have part 3 of the 6-part The Neu­ro­bi­ol­ogy of Stress series. If you are join­ing the series now, you can read the pre­vi­ous part Here.)

Stayin’ Alive

Under­stand­ing the Human Brain and How It Responds to Stress

The Lit­tle Brain Down Under

The tour con­tin­ues … Sit­ting under the occip­i­tal and tem­po­ral lobes of the brain is the cere­bel­lum. It’s about the size of a child’s fist. Because it looks like a sep­a­rate brain­like struc­ture attached to the under­side of the cor­tex, the cere­bel­lum is some­times referred to as the “ lit­tle brain. ” It’s con­nected to the brain stem, which in turn con­nects the brain to the spinal cord. The cere­bel­lum used to be rel­e­gated to the very sim­ple role of help­ing us main­tain bal­ance when we walk or run, but mod­ern neu­ro­science has found that the cere­bel­lum plays a much larger and more impor­tant role than that. Read the rest of this entry »

(Editor’s note:  below you have part 2 of the 6-part The Neu­ro­bi­ol­ogy of Stress series. If you are join­ing the series now, you can read the pre­vi­ous part Here.)

Stayin’ Alive

Gray Mat­ters

The term gray mat­ter usu­ally evokes an image of the cor­tex, because that ’ s the part most vis­i­ble in pic­tures of the brain.  In fact, gray mat­ter makes up not only the cere­bral cor­tex but also the cen­tral por­tion of the spinal cord and areas called the cere­bel­lar cor­tex and the hip­pocam­pal cor­tex.  This dense tis­sue is packed full of neu­ronal cells, their den­drites (branch­ing, root — like end­ings), axon ter­mi­nals (the other end), and those sticky glial cells I men­tioned ear­lier. The cor­tex is the area of the brain where the actual pro­cess­ing of infor­ma­tion takes place.  Because of its rel­a­tive size and com­plex­ity, it ’ s easy to under­stand why it plays a key role in mem­ory, atten­tion, per­cep­tual aware­ness, thought, lan­guage, and consciousness.

Read the rest of this entry »

(Editor’s note: We are pleased to bring to Sharp­Brains read­ers a new 6-part series on the Neu­ro­bi­ol­ogy of Stress, excerpted from the recent book Nowhere to Hide: Why Kids with ADHD and LD Hate School and What We Can Do About It, by Sharp­Brains con­trib­u­tor Dr. Jerome Schultz.)

Stayin ’ Alive

Worry is like a rock­ing chair. It gives you some­thing to do, but it gets you nowhere.
— Erma Bombeck

The brain is the con­trol cen­ter for all of our thoughts, actions, atti­tudes, and emo­tions. It ’ s the pilot­house on the river­boat of our lives. It’s Mis­sion Con­trol for all of our fl ights into space or time. It ’ s the air traffic con­troller that helps us nav­i­gate and reroute our paths based on incom­ing and out­go­ing infor­ma­tion and how we’re feel­ing about it at the time. It’s the John Williams of our per­sonal sym­phony. It ’ s the Mother Ship to our Starfleet; it’s . . . (Uh, sorry, I got car­ried away there, but I think you get my point!) Read the rest of this entry »

Here you are have the bi-monthly Digest of our most Pop­u­lar blog posts. (Also, remem­ber that you can sub­scribe to receive our blog RSS feed, or to our newslet­ter at the top of this page if you want to receive this digest by email).

Brain Fit­ness News and Events

Upcom­ing Events: I will be speak­ing at five Health, Edu­ca­tion and Gam­ing events over the next cou­ple of months to intro­duce find­ings from our recent mar­ket report. Please intro­duce your­self if you attend any of these events.

Pre­vent­ing Mem­ory Loss-Special Issue: Con­gres­sional Quar­terly Researcher, one of the main pub­li­ca­tions on Capi­tol Hill, pub­lished an impres­sive 24-page spe­cial issue titled Pre­vent­ing Mem­ory Loss. Highly rec­om­mended if you want to be on top of the lat­est research trends and their pol­icy implications.

Read the rest of this entry »

Very good arti­cle in the LA Times today. Like a Stair­Mas­ter for the brain: Can men­tal work­outs improve the mind’s agility? Baby boomer con­cerns stim­u­late an indus­try expan­sion.

The reporter, Melissa Healy, reviews the healthy aging seg­ment in the Brain Fit­ness field. A few selected quotes:

- “There is plau­si­bil­ity, both bio­log­i­cal and behav­ioral, to the claim that these may work,” says Molly Wag­ster, chief of the National Insti­tute on Aging’s neu­ropsy­chol­ogy branch. “But it is still a sit­u­a­tion of ‘buyer beware.’ ”

- “I see this as a new fron­tier of fit­ness over­all,” says Alvaro Fer­nan­dez, founder and chief exec­u­tive of the web­site Sharp­Brains .com, which tracks the busi­ness and sci­ence of brain-training. Amer­i­cans already under­stand the value of phys­i­cal fit­ness as a means of pre­serv­ing the body’s proper func­tion and pre­vent­ing age-related dis­eases, says Fer­nan­dez. He pre­dicts that cog­ni­tive fit­ness will become a goal to which Amer­i­cans equally aspire as we learn more about aging and the brain.
– (Dr. Elkhonon) Gold­berg, who pro­vides sci­en­tific advice on the web­site http://www.sharpbrains.com/, says that as neu­ro­sci­en­tists use imag­ing tech­nolo­gies to “see” the cel­lu­lar changes that come with learn­ing, he grows more con­fi­dent that well-designed train­ing pro­grams can have dis­cernible every­day effects in pre­serv­ing or repair­ing the intel­lec­tual func­tion of older adults. “This is shared hard­ware” that’s being changed in the brain, “and to the extent you some­how enhance it, that will have wide-ranging effects,” Gold­berg says. “It pro­vides a much more com­pelling raison­tre for this whole business.”

The arti­cle adds that “Amer­i­cans this year are expected to invest $225 mil­lion in these pro­grams — up from just $70 mil­lion in 2003 — in an effort to tune up the brain, strengthen the mem­ory and fore­stall or reverse the cog­ni­tive slip­page that often comes with age, psy­chi­atric dis­ease, stroke or med­ical treatments.”

Our break­down for those 2007 US pre­dic­tions are as fol­lows: $80m for the Con­sumer seg­ment, $60m in K12 Edu­ca­tion, $50m in Clin­i­cal appli­ca­tions, and $35m in the Cor­po­rate seg­ment. The Con­sumer seg­ment, with a healthy aging value propo­si­tion, is the most recent one but the most rapidly growing.

Read the full arti­cle: Like a Stair­Mas­ter for the brain.

PS: the arti­cle also says “In the last three years, these brainpower-boosting pro­grams have pro­lif­er­ated, with names like Mind­Fit, Happy Neu­ron, Brain Fit­ness and Lumos­ity.”.. if there are reporters read­ing this, please avoid future con­fu­sion by nam­ing Posit Science’s pro­gram “Posit Sci­ence Brain Fit­ness Pro­gram 2.0″. Brain Fit­ness refers to the full category.

Today we inter­view Dr. Arthur Lavin, Asso­ciate Clin­i­cal Pro­fes­sor of Pedi­atrics at Case West­ern School of Med­i­cine, pedi­a­tri­cian in pri­vate prac­tice, and one of the first providers of Cogmed Work­ing Mem­ory Train­ing in the US (the pro­gram whose research we dis­cussed with Dr. Torkel Kling­berg and Dr. Bradley Gib­son). Dr. Lavin has a long stand­ing inter­est in technology-as evi­denced by Microsoft’s recog­ni­tion of his paper­less office– and in brain research and applications-he trained with esteemed Mel Levine from All Kinds of Minds-.

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Key take-aways:

- Schools today are not yet in a posi­tion to effec­tively help kids with cog­ni­tive issues deal with increas­ing cog­ni­tive demands.

- Work­ing Mem­ory is a cog­ni­tive skill fun­da­men­tal to plan­ning, sequenc­ing, and exe­cut­ing school-related work.

- Work­ing Mem­ory can be trained, as evi­denced by Dr. Lavin’s work, based on Cogmed Work­ing Mem­ory Train­ing, with kids who have atten­tion deficits.

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Con­text on cog­ni­tive fit­ness and schools

AF (Alvaro Fer­nan­dez): Dr. Lavin, thanks for being with us. It is not very com­mon for a pedi­a­tri­cian to have such an active inter­est in brain research and cog­ni­tive fit­ness. Can you explain the source of your interest?

AL (Arthur Lavin): Through­out my life I have been fas­ci­nated by how the mind works. Both from the research point of view and the prac­ti­cal one: how can sci­en­tists’ increas­ing knowl­edge improve kids’ lives? We now live in an truly excit­ing era in which solid sci­en­tific progress in neu­ro­science is at last cre­at­ing oppor­tu­ni­ties to improve people’s actual cog­ni­tive func­tion. The progress Cogmed has achieved in cre­at­ing a pro­gram that can make great dif­fer­ences in the lives of chil­dren with atten­tion deficits is one of the most excit­ing recent devel­op­ments. My col­league Ms. Susan Glaser and I recently pub­lished two books: Who’s Boss: Mov­ing Fam­i­lies from Con­flict to Col­lab­o­ra­tion (Col­lab­o­ra­tion Press, 2006) and Baby & Tod­dler Sleep Solu­tions for Dum­mies (Wiley, 2007), so I not only see myself as a pedi­a­tri­cian but also an edu­ca­tor. I see par­ents in real need of guid­ance and sup­port. They usu­ally are both very skep­ti­cal, since Read the rest of this entry »