Inter­est­ing arti­cle on The Dana Foun­da­tion web­site on how to mon­i­tor cog­ni­tive decline in the brain in the very early stages of Alzheimer’s: Func­tional MRI May Be Use­ful for Mon­i­tor­ing Cog­ni­tive Decline in the Elderly (Dana Foundation)

Alzheimer’s researchers have long wanted to find bet­ter ways not only to diag­nose the dis­ease but also to mon­i­tor its pro­gres­sion from the ear­li­est stages.

A new study sug­gests that func­tional mag­netic res­o­nance imag­ing (fMRI), a tech­nique cur­rently used mainly for neu­ro­science research or to guide brain surgery, could be use­ful in this clin­i­cal role.

[…] an ele­gant and thought-provoking study.

(Editor’s Note: I recently came across an excel­lent book and resource, The Alzheimer’s Action Plan: The Experts’ Guide to the Best Diag­no­sis and Treat­ment for Mem­ory Prob­lems, recently released in paper­back. Dr. Murali Doraiswamy, one of the authors and lead­ing Alzheimer’s expert, kindly helped us cre­ate a 2-part arti­cle series to share with Sharp­Brains read­ers advice on a very impor­tant ques­tion, “How can we help the pub­lic at large to dis­tin­guish Alzheimer’s Dis­ease from nor­mal aging — so that an inter­est in early iden­ti­fi­ca­tion doesn’t trans­late into unneeded wor­ries?” What fol­lows is an excerpt from the book, pages 72–78, dis­cussing the Pros and Cons of the most com­mon assessments).

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While no sin­gle test (other than a brain biopsy, which is a very inva­sive and risky pro­ce­dure) can con­clu­sively prove that a per­son has Alzheimer’s, many tests can give us a good idea. A list of all the tests that help us assess mem­ory and think­ing prob­lems appears at the end of this chap­ter. Mean­while, let’s take a good look at the whys and hows of a thor­ough mem­ory assessment.

WHAT A DIFFERENCE AN EXTRA TEST CAN MAKE

To under­stand why get­ting tested (and retested as symp­toms change and the dis­ease pro­gresses) is impor­tant, check out the expe­ri­ence of Kather­ine, who went to the doc­tor com­plain­ing of a mem­ory slow­down. She took five of the most impor­tant neu­ropsy­cho­log­i­cal tests, which assess brain func­tion with­out actu­ally phys­i­cally look­ing at the brain. Then she under­went brain scans, a car­dio­vas­cu­lar workup, and blood tests to see what else was going on that might be under­min­ing her men­tal func­tion. Read the rest of this entry »

If you could, you would. You can, but pre­fer not to know it?

More than any other organ, your brain is up to you. You are what you think, not just what you eat. Here’s some food for thought:

Design your Mind

Set­ting cog­ni­tive and behav­ioral goals raises chal­leng­ing and wor­thy ques­tions: What do you want from your brain? Will you know it when you achieve it?

To attain the brain of our choos­ing, we must under­stand our selves and cur­rent abil­i­ties. Intro­spec­tion and curios­ity are help­ful if they trig­ger and sus­tain the effort to enrich the mind. How­ever, objec­tive infor­ma­tion which leads to informed assess­ment of brain func­tion is often lacking.

Mind your Brain

Hon­esty. Open­ness. Self-awareness.

Irrefutable virtues, but in prac­tice most peo­ple fall short. Few reg­u­larly appraise their brain skills; even so, the abil­ity to accu­rately judge one’s own men­tal per­for­mance is not guar­an­teed. I believe the first step to mind­ing the brain is shed­ding hang-ups while offer­ing and solic­it­ing frank feed­back from fam­ily and close con­fi­dants. In the clin­i­cal set­ting, rou­tine cog­ni­tive screen­ing and “men­tal check ups” are not cur­rently prac­ticed, in part due to time con­straints and lim­ited util­ity of tra­di­tional paper-and-pencil tests. From a pub­lic health per­spec­tive, the U.S. Pre­ven­ta­tive Task Force reviewed Read the rest of this entry »