(Editor’s note: below you have part 4 of the 6-part The Neu­ro­bi­ol­ogy of Stress series. If you are join­ing the series now, you can read the pre­vi­ous part Here.)

Stayin’  Alive

THE STRESS RESPONSE EXPLAINED

Stress was put on the map, so to speak, by a Hun­gar­ian — born Cana­dian endocri­nol­o­gist named Hans Hugo Bruno Selye (ZEL — yeh) in 1950, when he pre­sented his research on rats at the annual con­ven­tion of the Amer­i­can Psy­cho­log­i­cal Asso­ci­a­tion. To explain the impact of stress, Selye pro­posed some­thing he called the Gen­eral Adap­ta­tion Syn­drome (GAS), which he said had three com­po­nents. Accord­ing to Selye, when an organ­ism expe­ri­ences some novel or threat­en­ing stim­u­lus it responds with an alarm reac­tion. This is fol­lowed by what Selye referred to as the recov­ery or resis­tance stage, a period of time dur­ing which the brain repairs itself and stores the energy it will need to deal with the next stress­ful event.

Read the rest of this entry »

A few eter­nal ques­tions:
– Is caf­feine good for the brain?
– Does it boost cog­ni­tive func­tions?
– Does it pro­tect against dementia?

There is lit­tle doubt that drink­ing that morn­ing cup of cof­fee will likely increase alert­ness, but the main ques­tions that research is try­ing to answer go beyond that. Basi­cally: is there a sus­tained, life­time, ben­e­fit or harm from drink­ing cof­fee regularly?

The answer, so far, con­tains good news and bad news. The good news for cof­fee drinkers is that most of the long-term results are direc­tion­ally more pos­i­tive than neg­a­tive, so no clear harm seems to occur. The bad news is that it is not clear so far whether caf­feine has ben­e­fi­cial effects on gen­eral brain func­tions, either short-term or long-term (aged-related decline or risks of dementia).

It is impor­tant to note that many of the stud­ies show­ing an effect of cof­fee con­sump­tion on brain func­tions or risks of demen­tia report a cor­re­la­tion or asso­ci­a­tion (they are not ran­dom­ized clin­i­cal tri­als). As you know, cor­re­la­tion doesn’t prove cau­sa­tion: cof­fee drinkers may seem to do well in a num­ber in these long-term stud­ies, but there may be other rea­sons why cof­fee drinkers do better.

Q: How does caf­feine affect my brain?
A: Caf­feine is a stimulant.

It belongs to a chem­i­cal group called xan­thine. Adeno­sine is a nat­u­rally occur­ring xan­thine in the brain that slows down the activ­ity of brain cells (neu­rons). To a neu­ron, caf­feine looks like adeno­sine. It is there­fore used by some neu­rons in place of adeno­sine. The result is that these neu­rons speed up instead of slow­ing down.

This increased neu­ronal activ­ity trig­gers the release of the adren­a­line hor­mone, which will affect your body Read the rest of this entry »

Below you have a very insight­ful arti­cle on stress by one of our new Expert Con­trib­u­tors, Gre­gory Kel­let, a researcher at UCSF. Enjoy! (Credit for Pic of Vic­to­ria Crater in Mars: Mars Recon­nais­sance Orbiter, via Wikipedia).

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“My brain is fried, toast, fraz­zled, burnt out. How many times have you said or heard one ver­sion or another of these state­ments. Most of us think we are being fig­u­ra­tive when we utter such phrases, but research shows that the bio­log­i­cal con­se­quences of sus­tained high lev­els of stress may have us being more accu­rate than we would like to think.

Crash Course on Stress

Our bod­ies are a com­plex bal­anc­ing act between sys­tems work­ing full time to keep us alive and well. This bal­anc­ing act is con­stantly adapt­ing to the myr­iad of changes occur­ring every sec­ond within our­selves and our envi­ron­ments. When it gets dark our pupils dilate, when we get hot we sweat, when we smell food we sali­vate, and so forth. This con­stant bal­anc­ing act main­tains a range of sta­bil­ity in the body via change; and is often referred to as allosta­sis. Any change which threat­ens this bal­ance can be referred to as allo­sta­tic load or stress.

Allo­sta­tic load/stress is part of being alive. For exam­ple just by get­ting up in the morn­ing, we all expe­ri­ence a very impor­tant need to increase our heart rate and blood pres­sure in order to feed our newly ele­vated brain. Although usu­ally man­age­able, this is a change which the body needs to adapt to and, by our def­i­n­i­tion, a stressor.

Stress is only a prob­lem when this allo­sta­tic load becomes over­load. When change is exces­sive or Read the rest of this entry »

We are very excited to announce sub­mis­sions are open for our Brain Essay Con­test held in con­junc­tion with four other blogs. The hosts are:

• A Blog Around The Clock
• Neu­rophi­los­o­phy
• Pos­i­tive Psy­chol­ogy News Daily
• Sharp­Brains
• The Quick and the Ed

The goal of this con­test is to con­nect high-school stu­dents and teach­ers of biol­ogy and psy­chol­ogy with sci­ence and psy­chol­ogy blog­gers. Stu­dents will need to answer in 400–800 words:

“Based on brain and mind research (within the past 5 years),

1. How do we learn?
2. How can this new knowl­edge improve edu­ca­tion and the lives of all people?”

Sub­mis­sions are due by May 10, 2007.

The ten best essays, as selected by the jury of the host blogs, will be posted on the host blogs and entered into blog car­ni­vals. The win­ners will gain recog­ni­tion in the blo­go­phere and get a com­pli­men­tary annual sub­scrip­tion to Tuition­Coach, a per­son­al­ized, internet-based pro­gram that de-mystifies the col­lege finan­cial aid process for stu­dents and their fam­i­lies and helps fam­i­lies find the best options to finance col­lege choices.

Are you a high school stu­dent? Do you know a high school stu­dent? If so, get those key­boards warmed up and send us your best!

Here you have some use­ful advice from a fel­low blog­ger.