SharpBrains

This is a partial list of the literature we reviewed during the research phase of our new book, The SharpBrains Guide to Brain Fitness.  We know many friends of SharpBrains are researchers, healthcare professionals, graduate/ Ph.D. students, who want have direct access to the references (perhaps PubMed should promote itself as a never ending source of mental stimulation?), so here you have this list, organized by relevant chapter. Please note that the list below appears in the book - whose manuscript we had to close in January 2009.

Introduction

• Basak, C. et al. (2008). Can training in a real-time strategy video game attenuate cognitive decline in older adults? Psychology and Aging.
• Begley, S. (2007). Train your mind, change your brain: How a new science reveals our extraordinary potential to transform ourselves. Ballantine Books.
• DeKosky, S. T., et al. (2008). Ginkgo biloba for prevention of dementia: a randomized controlled trial. Journal of the American Medical Association, 300, 2253-2262.
• Doidge, N. (2007). The Brain that changes itself: Stories of personal triumph from the frontiers of brain science. Viking Adult.

Chapter 1. The Brain and Brain Fitness 101

• Bunge, S. A., & Wright, S. B. (2007). Neurodevelopmental changes in working memory and cognitive control. Current Opinion In Neurobiology, 17(2), 243-50.
• Damasio, A. (1995). Descartes’ error: Emotion, reason, and the human brain. Penguin Press.
• David Kolb, D. (1983). Experiential learning: Experience as the source of learning and development. FT Press.
• Draganski, B., Gaser, C., Kempermann, G., Kuhn, H. G., Winkler, J., Buchel, C., & May A. (2006). Temporal and spatial dynamics of brain structure changes during extensive learning. The Journal of Neuroscience, 261231, 6314-6317.
• Gage, F. H., Kempermann, G., & Song, H. (2007). Adult Neurogenesis. Cold Spring Harbor Laboratory Press, NY.
• Gardner, H. (1983). Frames of Mind: The theory of multiple intelligences. New York: Basic Books.
• Gaser, C. & Schlaug, G. (2003). Brain structures differ between musicians and non-musicians. The Journal of Neuroscience, 23, 9240-9245. Continue Reading »

Dr. Andrew Newberg is an Associate Professor in the Department of Radiology and Psychiatry and Adjunct Assistant Professor in the Department of Religious Studies at the University of Pennsylvania. He has published a variety of neuroimaging studies related to aging and dementia. He has also researched the neurophysiological correlates of meditation, prayer, and how brain function is associated with mystical and religious experiences.

Dr. Newberg, thank you for being with us today. Can you please explain the source of your interests at the intersection of brain research and spirituality?

Since I was a kid, I had a keen interest in spiritual practice. I always wondered how spirituality and religion affect us, and over time I came to appreciate how science can help us explore and understand the world around us, including why we humans care about spiritual practices. This, of course, led me to be particularly interested in brain research.

During medical school I was particularly attracted by the problem of consciousness. I was fortunate to meet researcher Dr. Eugene D'Aquili in the early 1990s, who had been doing much research on religious practices effect on brain since the 1970s. Through him I came to see that brain imaging can provide a fascinating window into the brain.

Can we define religion and spirituality -which sound to me as very different brain processes-, and why learning about them may be helpful from a purely secular, scientific point of view?

Good point, definitions matter, since different people may be searching for God in different ways. I view being religious as participating in organized rituals and shared beliefs, such as going to church. Being spiritual, on the other hand, is more of an individual practice, whether we call it meditation, or relaxation, or prayer, aimed at expanding the self, developing a sense of oneness with the universe.

What is happening is that specific practices that have traditionally been associated with religious and spiritual contexts may also be very useful from a mainstream, secular, health point of view, beyond those contexts. Scientists are researching, for example, what Continue Reading »

You may have seen this insighful OpEd last Friday in the New York Times, by clinical neuropsychologist Gerald Tramontano:

Head Games

- "CHILDREN aged 5 to 18 suffer at least 96,000 sports-related concussions every year in the United States, the Centers for Disease Control and Prevention estimates. Even more troubling, as many as 20 percent of all high school football players sustain concussions annually, studies show."

- "The only way to know for sure whether a concussion victim’s brain has returned to normal is to compare the results of neuropsychological tests conducted before and after the injury. That requires preparing athletes for the season by putting them through baseline testing."

Comment: Great OpEd, raising awareness of a problem with growing importance - not only in terms of sports concussions, but also car accidents, strokes, and a variety of life-events that may provoke brain damage - and introducing readers to the need for cognitive baselines for specific individuals.

Now, we will probably need to go further than the author of the OpEd suggests. There are simply not enough neuropsychologists in the whole planet to test one-person at a time for 4-hours each, and the cost of trying so would be astronomical.

The more realistic route is to combine a) fully-automated computer-based assessments as a baseline, b) the involvement of a neuropsychologist when needed, probably both to supervise the whole assessment program for a sports team, for example, and then to supervise the post-damage rehabilitation process.

Good article on the August edition of Military Officer magazine:

Mental Floss (August 2008) (link opens a PDF-life document, you can read the text by Zooming In).

My 2 favorite quotes, both by Dr. Molly Wagster, chief of the Neuropsychology of Aging Branch, National Institute on Aging (NIA) in Bethesda, Md:

- "Certainly as we age there are declines with brain functions and cognition. But there's evidence that the aging brain can adapt and change more than we ever thought".

- "We don't know how it happens or how long changes last, but even in the face of these unanswered questions, there is the chance to maintain our cognitive function".

Let me add a  reflection: who among us won't be tomorrow one day older than he/she is today? The good news about the "aging brain" doesn't only refer to adults over 70!

To explore these concepts in more depth, you may enjoy visiting our Neuroscience Interview Series.

July is shaping up to be a fascinating month, full of cognitive health research reports and applications. Here you have a roundup, covering food for the brain, cognitive assessments, mental training and DNA, and more.

1) Brain foods: the effects of nutrients on brain function (Nature Neuroscience)