There's such a flood of very significant research studies, educational resources and articles related to brain health, it's hard to keep track - even for us!

Let me introduce and quote some of the top Brain Health Studies, Articles and Resources published in March:

1) Cognitive Decline Begins In Late 20s, Study Suggests (Science Daily)

- "These patterns suggest that some types of mental flexibility decrease relatively early in adulthood, but that how much knowledge one has, and the effectiveness of integrating it with one's abilities, may increase throughout all of adulthood if there are no pathological diseases," Salthouse said.

- However, Salthouse points out that there is a great deal of variance from person to person

2) Cerebrum 2009: Emerging Ideas in Brain Science - new book by the Dana Foundation that "explores the cutting edge of brain research and its implications in our everyday lives, in language understandable to the general reader."

A couple of excellent chapters of direct relevance to everyone's brain health are:
- Chapter 4: A Road Paved by Reason, by Elizabeth Norton Lasley

- Chapter 10: Neural Health: Is It Facilitated by Work Force Participation?, by Denise Park, Ph.D

3) Staying Sharp DVD Program: "Dr. Jordan Grafman, chief of the Cognitive Neuroscience Section at the National Institute of Neurological Disorders and Stroke outside of Washington, DC, and a member of the Dana Alliance for Brain Initiatives, is your guide as we cover what to expect from the aging brain and what we can do to 'stay sharp.'

For a free DVD of this program you can contact stayingsharp@dana.org. (they say free in their website, I don't know if that includes shipping & handling)

4) Drivers to be tested on cognitive ability starting at age 75 (Japan Times)

The outline of a cognitive test that drivers aged 75 or over will be required to take from June when renewing their licenses was released Thursday...The test is intended to reduce the number of traffic accidents involving elderly drivers by measuring their cognitive level.

5) Physical Fitness Improves Spatial Memory, Increases Size Of Brain Structure (Science Daily)

- "Now researchers have found that elderly adults who are more physically fit tend to have bigger hippocampi and better spatial memory than those who are less fit."

6) Brain Trainers: A Workout for the Mind (Scientific American Mind)

"I recently tried out eight of the latest brain fitness programs, training with each for a week. The programs ranged widely in focus, quality and how fun they were to use. “Like physical exercise equipment, a brain exercise program doesn’t do you any good if you don’t use it,” says Andrew J. Carle, director of the Program in Assisted Living/Senior Housing Administration at George Mason University. And people tend not to use boring equipment. “I remember when NordicTrack was the biggest thing out there. Everyone ran out and bought one, and 90 percent of them ended up as a clothes rack in the back of your bedroom.”

The reporter used: Posit Science's Brain Fitness Program Classic, HappyNeuron, Nintendo BrainAge, CogniFit's MindFit/ CogniFit Personal Coach, Lumosity, MyBrainTrainer, BrainTwister, Cogmed Working Memory Training.

7) The Latest in Mental Health: Working Out at the 'Brain Gym' (Wall Street Journal)

- "Marshall Kahn, an 82-year-old family doctor in Fullerton, Calif., says he got such a boost from brain exercises he started doing at a "Nifty after Fifty" club that he decided to start seeing patients again part-time. "Doing all the mental exercise," he says, "I realized I've still got it."

8) Debate Over Drugs For ADHD Reignites (Washington Post)

- "New data from a large federal study have reignited a debate over the effectiveness of long-term drug treatment of children with hyperactivity or attention-deficit disorder, and have drawn accusations that some members of the research team have sought to play down evidence that medications do little good beyond 24 months."

- "The study also indicated that long-term use of the drugs can stunt children's growth."

8) Adaptive training leads to sustained enhancement of poor working memory in children (Developmental Science)

Abstract: Working memory plays a crucial role in supporting learning, with poor progress in reading and mathematics characterizing children with low memory skills. This study investigated whether these problems can be overcome by a training program designed to boost working memory. Children with low working memory skills were assessed on measures of working memory, IQ and academic attainment before and after training on either adaptive or non-adaptive versions of the program. Adaptive training that taxed working memory to its limits was associated with substantial and sustained gains in working memory, with age-appropriate levels achieved by the majority of children. Mathematical ability also improved significantly 6 months following adaptive training. These findings indicate that common impairments in working memory and associated learning difficulties may be overcome with this behavioral treatment.

9) Brain cortex thinning linked to inherited depression (Los Angeles Times)

- "On average, people with a family history of depression appear to have brains that are 28% thinner in the right cortex --- the outermost layer of the brain --- than those with no known family history of the disease. That cortical thinning, said the researchers, is on a scale similar to that seen in patients with Alzheimer's disease or schizophrenia."

Here you have 4 of the most popular brain games in our blog, plus a bonus stress management tip.

Brain Teaser 1. In which direction is the bus pictured below traveling?

Schoolbus

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My natural rhythms are in cycle with the school calendar. January 1st takes a back seat to my new year, which gets ushered in with the month of September when there is crispness in the air that gradually shakes off the slower, more relaxed pace of summer.Conveniently, my career in teaching meshes with my natural cyclical year. And as this year draws to a close, I am re-energized by the pace of summer, knowing that anything may pop in to my mind as I engage in activities not directly related to school. But before that happens, I’d like to reflect on this past year, in particular as it was my first year of blogging about the brain.

My interest in the brain stems from wanting to better understand both how to make school more palatable for students, and professional development more meaningful for faculty. To that end, I began my Neurons Firing blog in April, 2007, have been doing a lot of reading, and been attending workshops and conferences, including Learning & the Brain.

If you agree that our brains are designed for learning, then Continue Reading »

I just read a very interesting article in Newsweek: Executive Functions: The School Skill That May Matter More Than IQ. A few quotes:

- "But recent advances in psychology and brain science are now suggesting that a child's ability to inhibit distracting thoughts and stay focused may be a fundamental cognitive skill, one that plays a big part in academic success from The Executive Brain by Elkhonon Goldbergpreschool on. Indeed, this and closely related skills may be more important than traditional IQ in predicting a child's school performance."

- "EF (executive functions) comprises not only effortful control and cognitive focus but also working memory and mental flexibility—the ability to adjust to change, to think outside the box."

- "When the teacher holds up a circle they clap, with a triangle they hop, and so forth. The kids are taught to talk themselves through the mental exercise: "OK, now clap." "Twirl now." This has been shown to flex and enhance the brain's ability to switch gears, to suppress one piece of information and sub in a new one. It takes discipline; it's the elementary school equivalent of saying "I really need stop thinking about next week's vacation and focus on this report."

The main points: executive functions are crucial for success in life, AND they can be trained. I couldn't agree more with the article in that cognitive training should be part of the education curriculum and receive more research dollars to determine exactly how to best do so.

I read another very interesting article on Alzheimer's Disease. Which may look like a completely different topic than the one above...but please bear with me. Continue Reading »

The MIT Technology Review September/ October edition brings an article by Daniel Dennett titled Higher Games: It's been 10 years since IBM's Deep Blue beat Garry Kasparov in chess. A prominent philosopher asks what the match meant (subscription required), which is creating a lot of buzz on the science blogosphere on whether humans or machines are "smarter".  

GABA ReceptorAll this begs the question, what does "being smart" means? "Is it possible to improve intelligence and become "smarter" and what does it really mean to be "smarter?" (question asked by Patricia, one of our readers).

Today we bring you an answer to those questions provided by David Gamon, author of Building Mental Muscle: Conditioning Exercises for the Six Intelligence Zones:

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As we age, our brains accumulate an ever larger collection of patterns. This gives us a kind of mental quickness that compensates for the slowing of processing speed. Instead of having to piece together the pattern bit by bit from scratch by associating individual pieces of data, you need only a few pieces of data to make you realize that they fit a pattern you already know, much the way a few bars of melody are all you need to recognize an entire song.

The more experience we accumulate, the more of these patterns we hold in our brains, and the less effort we have to make to piece together new pieces of data in new ways. With that comes a danger. We get lazy. It’s a lot easier to Continue Reading »

We hope you are enjoying the growing coverage of Brain Fitness as much as we are. Below you have the Brain Fitness Newsletter we sent a few days ago-you can subscribe to this monthly email update in the box on the right hand side.

In this post, we will briefly cover:

I. Press: see what CBS and Time Magazine are talking about. SharpBrains was introduced in the Birmingham News, Chicago Tribune and in a quick note carried by the American Psychological Association news service.

II. Events: we are outreach partners for the Learning & the Brain conference, which will gather neuroscientists and educators, and for the Dana Foundation’s Brain Awareness Week.

III. Program Reviews: The Wall Street Journal reviewed six different programs for brain exercise and aging, and the one we offer is one of the two winners. A college-level counseling center starts offering our stress management one. And we interview a Notre Dame scientist who has conducted a replication study for the working memory training program for kids with ADD/ ADHD.

IV. New Offerings: we have started to offer two information packages that can be very useful for people who want to better understand this field before they commit to any particular program: learn more about our Brain Fitness 101 guide and Exercise Your Brain DVD.

V. Website and Blog Summary: we revamped our home page and have had a very busy month writing many good articles. We also hosted two “Blog Carnivals”- don’t you want to know what that means?
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Continuing with the theme of a Week of Science sponsored by Just Science, we will highlight some of the key points in: Appelhans BM, Luecken LJ. Heart Rate Variability as an Index of Regulated Emotional Responding. Review of General Psychology. 2006;10:229–240.

Defining Heart Rate Variability
Effective emotional regulation depends on being able to flexibly adjust your physiological response to a changing environment.

"... heart rate variability (HRV) is a measure of the continuous interplay between sympathetic and parasympathetic influences on heart rate that yields information about autonomic flexibility and thereby represents the capacity for regulated emotional responding."

"HRV reflects the degree to which cardiac activity can be modulated to meet changing situational demands."

The sympathetic (SNS) and parasympathetic (PNS) branches of the autonomic nervous system (ANS) antagonistically influence the lengths of time between consecutive heartbeats. Faster heart rates, which can be due to increased SNS and/or lower PNS activity, correspond to a shorter interbeat interval while slower heart rates have a longer interbeat interval, which can be attributed to increased PNS and/or decreased SNS activity.

The frequency-based HRV analyses are based on the fact that the variations in heart rate produced by SNS and PNS activity occur at different speeds, or frequencies. SNS is slow acting and mediated by norepinephrine while PNS influence is fast acting and mediated by acetylcholine.

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For information on the 2008 Conference, and the discount for SharpBrains readers, visit: Learning & The Brain Conference: discount for SharpBrains readers.

The post below refers to the 2007 Conference: 

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The organizers of this amazing conference, whose registration is about to expire, just extended their very kind offer to SharpBrains readers: you can register at the reduced price of $475 (right now the normal price is $545) if you do so by February 9nd. You can register here http://www.edupr.com/reg.html, making sure to write SharpBrains1 in the comments section

This is what we wrote about the conference:

Talk about neuroscience applied to education: we will be reporting from a fascinating conference in San Francisco, February 15-17, titled Learning & the Brain: Enhancing Cognition and Emotions for Learning And Student Performance, sponsored by leading universities and the Dana Alliance for Brain Initiatives.

  • Speakers include a truly "Dream Team" of neuroscientists and educators such as Michael S. Gazzaniga, William C. Mobley, John D.E. Gabrieli, Robert M. Sapolsky, Robert Sylwester, and many many others. You can check the program here http://www.edupr.com/schedule2.htm.
  • The description of the event is: "Use this explosion of scientific knowledge to create new, powerful paradigms for teaching and healthcare. Cutting-edge discoveries in neuroscience may soon transform educational and clinical interventions by enhancing memory and cognition. Discover the influences of emotions, gender and the arts. Explore new ways to enhance cognition and to assess potential benefits and pitfalls of using pharmacology, technology and therapy to boost performance."

Update: we now have an in-depth interview with Yaakov Stern, leading advocate of the cognitive reserve theory, and one of the authors of the paper we review below: click on Build Your Cognitive Reserve-Yaakov Stern

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In honor of the Week of Science presented at Just Science from Monday, February 5, through Sunday, February 11, we will be writing about "just science" this week. We thought we would take this time to discuss more deeply some of the key scientific publications in brain fitness.

Today, we will highlight the key points in an excellent review of cognitive reserve: Scarmeas, Nikolaos and Stern, Yaakov. Cognitive reserve and lifestyle. Journal of Clinical and Experimental Neuropsychology. 2003;25:625-33.

What is Cognitive Reserve?
The concept of a cognitive reserve has been around since 1998 when a post mortem analysis of 137 people with Alzheimer's Disease showed that the patients exhibited fewer clinical symptoms than their actual pathology suggested. (Katzman et al. 1988) They also showed higher brain weights and greater number of neurons when compared to age-matched controls. The investigators hypothesized that the patients had a larger "reserve" of neurons and abilities that offset the losses caused by Alzheimer's. Since then the concept of cognitive reserve has been defined as the ability of an individual to tolerate progressive brain pathology without demonstrating clinical cognitive symptoms.
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The Wall Street Journal has a great article today, Putting Brain Exercises to the Test (requires subscription), that compares 6 different computer-based brain exercise programs along ease-of-use, fun, and science behind. We at SharpBrains conducted a very similar exercise last year, coming to basically the same conclusions.

The article compares Nintendo Brain Age, MyBrainBuilder, MyBrainTrainer, HappyNeuron, (CogniFit Science) MindFit and Posit Science brain fitness 2.0, and ends up recommending Continue Reading »

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