SharpBrains

This is a partial list of the literature we reviewed during the research phase of our new book, The SharpBrains Guide to Brain Fitness.  We know many friends of SharpBrains are researchers, healthcare professionals, graduate/ Ph.D. students, who want have direct access to the references (perhaps PubMed should promote itself as a never ending source of mental stimulation?), so here you have this list, organized by relevant chapter. Please note that the list below appears in the book - whose manuscript we had to close in January 2009.

Introduction

• Basak, C. et al. (2008). Can training in a real-time strategy video game attenuate cognitive decline in older adults? Psychology and Aging.
• Begley, S. (2007). Train your mind, change your brain: How a new science reveals our extraordinary potential to transform ourselves. Ballantine Books.
• DeKosky, S. T., et al. (2008). Ginkgo biloba for prevention of dementia: a randomized controlled trial. Journal of the American Medical Association, 300, 2253-2262.
• Doidge, N. (2007). The Brain that changes itself: Stories of personal triumph from the frontiers of brain science. Viking Adult.

Chapter 1. The Brain and Brain Fitness 101

• Bunge, S. A., & Wright, S. B. (2007). Neurodevelopmental changes in working memory and cognitive control. Current Opinion In Neurobiology, 17(2), 243-50.
• Damasio, A. (1995). Descartes’ error: Emotion, reason, and the human brain. Penguin Press.
• David Kolb, D. (1983). Experiential learning: Experience as the source of learning and development. FT Press.
• Draganski, B., Gaser, C., Kempermann, G., Kuhn, H. G., Winkler, J., Buchel, C., & May A. (2006). Temporal and spatial dynamics of brain structure changes during extensive learning. The Journal of Neuroscience, 261231, 6314-6317.
• Gage, F. H., Kempermann, G., & Song, H. (2007). Adult Neurogenesis. Cold Spring Harbor Laboratory Press, NY.
• Gardner, H. (1983). Frames of Mind: The theory of multiple intelligences. New York: Basic Books.
• Gaser, C. & Schlaug, G. (2003). Brain structures differ between musicians and non-musicians. The Journal of Neuroscience, 23, 9240-9245. Continue Reading »

Arts education influences learning and other areas of cognition and may deserve a more prominent place in schools, according to a wave of recent neuroscience research.One recent study found that children who receive music instruction for just 15 months show strengthened connections in musically relevant brain areas and perform better on associated tasks, compared with students who do not learn an instrument.

A separate study found that children who receive training to improve their focus and attention perform better not only on attention tasks but also on intelligence tests. Some researchers suggest that arts training might similarly affect a wide range of cognitive domains. Educators and neuroscientists gathered recently in Baltimore and Washington, D.C., to discuss the increasingly detailed picture of how arts education changes the brain, and how to translate that research to education policy and the classroom. Many participants referred to the results of Dana Foundation-funded research by cognitive neuroscientists from seven leading universities over three years, released in 2008.

“Art must do something to the mind and brain. What is that? How would we be able to detect that?” asked Barry Gordon, a behavioral neurologist and cognitive neuroscientist at Johns Hopkins University, who spoke May 8 during the “Learning and the Brain” conference in Washington, D.C. “Art, I submit to you without absolute proof, can improve the power of our minds. However, this improvement is hard to detect.”

Study links music, brain changes

Among the scientists trying to detect such improvement, Ellen Winner, a professor of psychology at Boston College, and Gottfried Schlaug, a professor of neurology at Beth Israel Deaconess Medical Center and Harvard Medical School, presented research at the “Learning, Arts, and the Brain” summit May 6 in Baltimore. Their work measured, for the first time, changes to the brain as a result of music training.

For four years, Winner and Schlaug followed children ages 9 to 11, some of whom Continue Reading »

Working memory is our ability to store and manipulate information for a brief time. It is typically measured by dual-tasks, where the individual has to remember an item while simultaneously processing a sometimes unrelated piece of information. A widely used working memory task is the reading span task where the individual reads a sentence, verifies it, and then recalls the final word. Individual differences in working memory performance are closely related to a range of academic skills such as reading, spelling, comprehension, and mathematics. Crucially, there is emerging research that working memory predicts learning outcomes independently of IQ. One explanation for the importance of working memory in academic attainment is that because it appears to be relatively unaffected by environmental influences, such as parental educational level and financial background, it measures a student’s capacity to acquire knowledge rather than what they have already learned.

However little is known about the consequences of low working memory capacity per se, independent of other associated learning difficulties. In particular, it is not known either what proportion of students with low working memory capacities has significant learning difficulties or what their behavioral characteristics are. The aim of a recent study published in Child Development (reference below) was to provide the first systematic large-scale examination of the cognitive and behavioral characteristics of school-aged students who have been identified solely on the basis of very low working memory scores.

In screening of over 3000 school-aged students in mainstream schools, 1 in 10 was identified as having working memory difficulties. There were several key findings regarding their cognitive skills. The first is that the majority of them performed below age-expected levels in reading and mathematics. This suggests that Continue Reading »

This is one of the slides I created recently for my talks, and it seems to be getting the point across.

Your answer?

The follow-up question: is your job and life more similar to the constant problem-solving and mental challenge of the cab driver, or to the routine or the bus driver?

Pascale wrote an excellent article on this, check it out: Brain Plasticity - How learning changes your brain.

Have a good Good Friday/ Passover/ holiday/ weekend!

Learning can be incidental. We all memorize facts without paying much attention to these facts or without willing to memorize them. However, when one really wants to memorize a fact, it is crucial to pay attention. Many studies have shown that compared to full attention conditions, dividing attention during study time leads to poor memory performance.

This exercise will help you practice focusing your attention.

It may seem easy but make sure you count twice!

Count the number of “Y” in this text:

Yesterday, Lucy went all the way to Boston. She wanted to buy new shoes. She had to go in many shops before she found the shoes she wanted. She was happy to stop at a restaurant to have some tea and cookies before she took the train back home.

Count the number of “F” in this text:

Finished files are the result of years of scientific study combined with the experience of years.
Count the number of “E” in this text:

Last summer, Jean and Harriet spent their vacation in Michigan. They rented a cabin on the lake. The cabin had two bedrooms and a nice deck. They used to spend a lot of time on the deck, just looking at how the light would change on the water. Several times, they borrowed bikes from their neighbors and spent a few hours exploring the villages not far from their cabin.

---
Solutions

There are 7 “Y” in the first text.

There are 6 "F" in the second text (got them?)
There are 38 “E” in the third text.

---

For many other Brain Teasers, click Here.
For many other teasers and articles by Dr. Michelon, click Here.

-- Pascale Michelon, Ph. D., is SharpBrains' Research Manager for Educational Projects. Dr. Michelon has a Ph.D. in Cognitive Psychology and has worked as a Research Scientist at Washington University in Saint Louis, in the Psychology Department. She conducted several research projects to understand how the brain makes use of visual information and memorizes facts. She is now an Adjunct Faculty at Washington University.

There's such a flood of very significant research studies, educational resources and articles related to brain health, it's hard to keep track - even for us!

Let me introduce and quote some of the top Brain Health Studies, Articles and Resources published in March:

1) Cognitive Decline Begins In Late 20s, Study Suggests (Science Daily)

- "These patterns suggest that some types of mental flexibility decrease relatively early in adulthood, but that how much knowledge one has, and the effectiveness of integrating it with one's abilities, may increase throughout all of adulthood if there are no pathological diseases," Salthouse said.

- However, Salthouse points out that there is a great deal of variance from person to person

2) Cerebrum 2009: Emerging Ideas in Brain Science - new book by the Dana Foundation that "explores the cutting edge of brain research and its implications in our everyday lives, in language understandable to the general reader."

A couple of excellent chapters of direct relevance to everyone's brain health are:
- Chapter 4: A Road Paved by Reason, by Elizabeth Norton Lasley

- Chapter 10: Neural Health: Is It Facilitated by Work Force Participation?, by Denise Park, Ph.D

3) Staying Sharp DVD Program: "Dr. Jordan Grafman, chief of the Cognitive Neuroscience Section at the National Institute of Neurological Disorders and Stroke outside of Washington, DC, and a member of the Dana Alliance for Brain Initiatives, is your guide as we cover what to expect from the aging brain and what we can do to 'stay sharp.'

For a free DVD of this program you can contact stayingsharp@dana.org. (they say free in their website, I don't know if that includes shipping & handling)

4) Drivers to be tested on cognitive ability starting at age 75 (Japan Times)

The outline of a cognitive test that drivers aged 75 or over will be required to take from June when renewing their licenses was released Thursday...The test is intended to reduce the number of traffic accidents involving elderly drivers by measuring their cognitive level.

5) Physical Fitness Improves Spatial Memory, Increases Size Of Brain Structure (Science Daily)

- "Now researchers have found that elderly adults who are more physically fit tend to have bigger hippocampi and better spatial memory than those who are less fit."

6) Brain Trainers: A Workout for the Mind (Scientific American Mind)

"I recently tried out eight of the latest brain fitness programs, training with each for a week. The programs ranged widely in focus, quality and how fun they were to use. “Like physical exercise equipment, a brain exercise program doesn’t do you any good if you don’t use it,” says Andrew J. Carle, director of the Program in Assisted Living/Senior Housing Administration at George Mason University. And people tend not to use boring equipment. “I remember when NordicTrack was the biggest thing out there. Everyone ran out and bought one, and 90 percent of them ended up as a clothes rack in the back of your bedroom.”

The reporter used: Posit Science's Brain Fitness Program Classic, HappyNeuron, Nintendo BrainAge, CogniFit's MindFit/ CogniFit Personal Coach, Lumosity, MyBrainTrainer, BrainTwister, Cogmed Working Memory Training.

7) The Latest in Mental Health: Working Out at the 'Brain Gym' (Wall Street Journal)

- "Marshall Kahn, an 82-year-old family doctor in Fullerton, Calif., says he got such a boost from brain exercises he started doing at a "Nifty after Fifty" club that he decided to start seeing patients again part-time. "Doing all the mental exercise," he says, "I realized I've still got it."

8) Debate Over Drugs For ADHD Reignites (Washington Post)

- "New data from a large federal study have reignited a debate over the effectiveness of long-term drug treatment of children with hyperactivity or attention-deficit disorder, and have drawn accusations that some members of the research team have sought to play down evidence that medications do little good beyond 24 months."

- "The study also indicated that long-term use of the drugs can stunt children's growth."

8) Adaptive training leads to sustained enhancement of poor working memory in children (Developmental Science)

Abstract: Working memory plays a crucial role in supporting learning, with poor progress in reading and mathematics characterizing children with low memory skills. This study investigated whether these problems can be overcome by a training program designed to boost working memory. Children with low working memory skills were assessed on measures of working memory, IQ and academic attainment before and after training on either adaptive or non-adaptive versions of the program. Adaptive training that taxed working memory to its limits was associated with substantial and sustained gains in working memory, with age-appropriate levels achieved by the majority of children. Mathematical ability also improved significantly 6 months following adaptive training. These findings indicate that common impairments in working memory and associated learning difficulties may be overcome with this behavioral treatment.

9) Brain cortex thinning linked to inherited depression (Los Angeles Times)

- "On average, people with a family history of depression appear to have brains that are 28% thinner in the right cortex --- the outermost layer of the brain --- than those with no known family history of the disease. That cortical thinning, said the researchers, is on a scale similar to that seen in patients with Alzheimer's disease or schizophrenia."

A person who helped reinvent "aging", "retirement" and "learning", contributing to the cognitive health of millions of individuals as a result:

Martin P. 'Marty' Knowlton dies at 88; co-founder of Elderhostel (Los Angeles Times)

- "Martin P. "Marty" Knowlton, a world traveler who fought ageism by co-founding Elderhostel, a program that pioneered learning vacations for mature adults, has died. He was 88."

- "Knowlton died Thursday of natural causes at a nursing home in Ventura, said David Bianco, who started Elderhostel with his friend in 1975."

- "When he was about 50, Knowlton became highly annoyed by two things: the prevailing wisdom that "as you got older, your mind automatically began to fail" and the government notifying him that "old age begins at 55," he told the Ventura County Star in 2000."

The article: Here

Elderhostel website: Here

Physical Fitness Improves Spatial Memory, Increases Size Of Brain Structure (Science Daily)

- "Now researchers have found that elderly adults who are more physically fit tend to have bigger hippocampi and better spatial memory than those who are less fit."

- "Certain activities are believed to modify hippocampus size in humans. For example, a study of London taxi drivers found that the posterior portion of the hippocampus was larger in experienced taxi drivers than in other subjects. And a study of German medical students found that the same region of the hippocampus increased in size as they studied for their final exams."

- "Studies also have found that the hippocampus shrinks with age, a process that coincides with small but significant cognitive declines. The rate at which this occurs, however, differs among individuals."

Related articles:

Physical Exercise and Brain Health

Brain Plasticity: How learning changes your brain

Last week, in this article's first part, we discussed the importance of actually teaching children how to get themselves into a physical state of being relaxed, explored several suggestions I hope you found useful.

Let's continue.

Teachers can help student overcome stress by teaching them to identify the impediments they might encounter in doing a certain task.

The teacher can ask:

What's going to get in the way of you doing this work?
He or she may have to jump-start the students’ thinking by suggesting such things as:
- competing events (family activities, friends call, IM-ing, new video game, etc.)
- lack of adequate place to study
- inadequate prior preparation or skills
- a negative attitude (this is not necessary, I can't do math, I’ll never need to know this, etc).
- health factors (I’m sick; I’m tired)

Conversely, teachers have to teach students to identify the enhancers; What's going to make it more likely that you will do this, and do this well?
(examples)
- I have confidence in my ability
- I feel competent in this skill
- I am committed to learning this because: I have the necessary resources to complete this task, such as materials, sources of information, people supports; parents, tutor, other kids

Teachers can turn distress into de-stress by using the Language of Success

The key is to de-emphasize PRAISE and emphasize SELF-APPRAISAL.

Teachers can encourage self-evaluation by Continue Reading »

Eric Jensen alerted me to a research study published in the February 4th Journal of Neuroscience --- Transgenerational Rescue of a Genetic Defect in Long-Term Potentiation and Memory Formation by Juvenile Enrichment. We both had the same initial WOW! feeling that we had experienced when we first read about the discovery of mirror neurons a decade+ ago.

The study's findings seemed to suggest that acquired characteristics can be genetically transmitted, a Lamarckinan belief that had long been discarded by biologists. This seemed improbable, so we decided to check out what the scientific community thought. It's the kind of research that educators certainly need to understand because the potential educational implications are profound, no matter how this particular study sorts out.

I've thus appended the following information below: (1) the abstract and reference of the original sttudy, (2) a link to a non-technical report in the current issue of New Scientist, (3) a link to a non- technical explanation of the research in Medical News Today, and (4) a link to a recent extended non-technical New Scientist article on the issue of non-genetic inheritance. Eric will post his commentary on the research in the March edition of his Brighter Brain Bulletin newsletter.

THE STUDY:

To put it simply: The researchers studied long-term potentiation (LTP), in which longer and more robust synaptic activation occurs. LTP is the basic mechanism for learning and memory formation.

Juvenile mice placed into an enriched environment (EE) developed enhanced LTP capabilities that they later transmitted to their own offspring during embryogenesis (rather than through later maternal instruction), and these effects persisted even when the offspring weren't in an EE. The study concluded that a stimulating juvenile environment can thus influence the composition of signaling networks that influence synaptic plasticity and memory formation in the enriched mouse, and also in its future offspring.

The problem with this research appears to be over whether the transmitted effects occurred via genetic changes or through something else in the mother's uterine environment. A female's eggs develop early in life to be distributed later, so it's improbable that a female's juvenile experiences would alter the DNA in her eggs. A more probable explanation may be that any changes in the mother's brain that occur via an EE are represented as currently ill- understood signaling molecules that pass through the placental barrier into the embryonic brain.

THE SIGNIFICANCE:

For educators, this research simply adds to our own strong belief that long-term benefits accrue from a stimulating early environment that encourages curiosity and exploration. The research builds on Continue Reading »