SharpBrains

This is a partial list of the literature we reviewed during the research phase of our new book, The SharpBrains Guide to Brain Fitness.  We know many friends of SharpBrains are researchers, healthcare professionals, graduate/ Ph.D. students, who want have direct access to the references (perhaps PubMed should promote itself as a never ending source of mental stimulation?), so here you have this list, organized by relevant chapter. Please note that the list below appears in the book - whose manuscript we had to close in January 2009.

Introduction

• Basak, C. et al. (2008). Can training in a real-time strategy video game attenuate cognitive decline in older adults? Psychology and Aging.
• Begley, S. (2007). Train your mind, change your brain: How a new science reveals our extraordinary potential to transform ourselves. Ballantine Books.
• DeKosky, S. T., et al. (2008). Ginkgo biloba for prevention of dementia: a randomized controlled trial. Journal of the American Medical Association, 300, 2253-2262.
• Doidge, N. (2007). The Brain that changes itself: Stories of personal triumph from the frontiers of brain science. Viking Adult.

Chapter 1. The Brain and Brain Fitness 101

• Bunge, S. A., & Wright, S. B. (2007). Neurodevelopmental changes in working memory and cognitive control. Current Opinion In Neurobiology, 17(2), 243-50.
• Damasio, A. (1995). Descartes’ error: Emotion, reason, and the human brain. Penguin Press.
• David Kolb, D. (1983). Experiential learning: Experience as the source of learning and development. FT Press.
• Draganski, B., Gaser, C., Kempermann, G., Kuhn, H. G., Winkler, J., Buchel, C., & May A. (2006). Temporal and spatial dynamics of brain structure changes during extensive learning. The Journal of Neuroscience, 261231, 6314-6317.
• Gage, F. H., Kempermann, G., & Song, H. (2007). Adult Neurogenesis. Cold Spring Harbor Laboratory Press, NY.
• Gardner, H. (1983). Frames of Mind: The theory of multiple intelligences. New York: Basic Books.
• Gaser, C. & Schlaug, G. (2003). Brain structures differ between musicians and non-musicians. The Journal of Neuroscience, 23, 9240-9245. Continue Reading »

Here you have the April edition of our monthly newsletter covering cognitive health and brain fitness topics. Please remember that you can subscribe to receive this Newsletter by email, using the box at the top of this page.

We are excited to release our 2009 market report The State of the Brain Fitness Software Market 2009. To be formally released on May 4th but available now for our clients and readers, this report aims to inform decision-makers at healthcare, insurance, research, public policy, investment and technology organizations about important developments in the brain fitness and cognitive health space.

2009 Market Report

The State of the Brain Fitness Software Market 2009: This new 150-page report finds sustained growth in the brain fitness software market (from $225m in 2007 to $265m in 2008) and promising seeds for future growth, combined with increased confusion given aggressive marketing claims and lack of education and standards. The report includes, for the first time, a Market & Research Momentum Matrix to categorize 21 key vendors, 10 Research Executive Briefs written by 12 leading scientists, and the complete results of our market survey with 2,000+ respondents. You can learn more, and acquire the report, Here.

News and Resources

Cognitive Health News April Round-Up: New cognitive track at the Games for Health conference, bilingual brains, poverty's effect on the brain and working memory due to stress, diabetes, neuroenhancing drugs, Kellogg's settlement with the FTC, neurocognitive testing in the military.

Normal Aging vs. Alzheimer's Disease: Dr. Murali Doraiswamy shares his very insightful views on the key question, "How can we help the public at large to distinguish Alzheimer's Disease from normal aging --- so that an interest in early identification doesn't translate into unneeded worries?", based on his recent book The Alzheimer's Action Plan.

Upcoming Guide

This is one of the slides I created recently for my talks, and it seems to be getting the point across.

Your answer?

The follow-up question: is your job and life more similar to the constant problem-solving and mental challenge of the cab driver, or to the routine or the bus driver?

Pascale wrote an excellent article on this, check it out: Brain Plasticity - How learning changes your brain.

Have a good Good Friday/ Passover/ holiday/ weekend!

Physical Fitness Improves Spatial Memory, Increases Size Of Brain Structure (Science Daily)

- "Now researchers have found that elderly adults who are more physically fit tend to have bigger hippocampi and better spatial memory than those who are less fit."

- "Certain activities are believed to modify hippocampus size in humans. For example, a study of London taxi drivers found that the posterior portion of the hippocampus was larger in experienced taxi drivers than in other subjects. And a study of German medical students found that the same region of the hippocampus increased in size as they studied for their final exams."

- "Studies also have found that the hippocampus shrinks with age, a process that coincides with small but significant cognitive declines. The rate at which this occurs, however, differs among individuals."

Related articles:

Physical Exercise and Brain Health

Brain Plasticity: How learning changes your brain

Spectacular article by Dr. Denise Park in this month's Cerebrum:

Working Later in Life May Facilitate Neural Health

- "Carmi Schooler at the National Institutes of Health, using a technique that allowed him to assess causal relationships, found that adults who performed intellectually challenging jobs across their life span showed more cognitive flexibility in late adulthood than those who performed less demanding jobs."
- "Perhaps the most compelling evidence regarding the impact of novel experiences on brain volume and function comes from a study at the Max Planck Institute in Germany. Adults with a mean age of 59 spent three months learning to juggle three balls. Although only about half the participants were able to achieve competence in this complex skill, those who succeeded had increased volume in a mediotemporal area of the visual cortex as well as the nucleus accumbens and the hippocampus, suggesting that sustained novel experience can increase the sizes of neural structures. Notably, the changes in the nucleus accumbens and hippocampus were Continue Reading »

As the Brain Fitness industry continues to gain momentum, and people explore all the incredible brain-training tools being developed, we hope that enthusiasts don't take their eye off the importance of the physical health of the brain and all the systems it communicates with. The brain is unique in that it houses our cognitive and emotional capacities in the form of the mind. It is a 'cognitive' organ that hungers for stimulation from new experiences and challenges. Many brain fitness programs strive to satisfy this need. Yet the brain is also a physical organ that plays by many of the same rules as the heart, lungs, liver and kidneys. To stay healthy and perform optimally it requires quality nutrition, physical activity and optimal sleep. The brain, especially, relies on a healthy vascular system to efficiently deliver oxygen and key nutrients and remove waste. In fact, the brain uses approximately 20% of the oxygen we breathe to satisfy its high-energy demands. Given that the brain only weighs about 2% of the body, we can consider it an energy hog and we must cater to its needs very carefully.

Nutrients play key roles in brain function. Several have shown efficacy in clinical trials treating cases of mood disorders, cognitive decline and of course benefiting the physical health of the brain. Nutrients are both the raw materials employed in creating new neural connections and Continue Reading »

In other words, may some foods be specifically good for brain function?

For a great in-depth review of the effects of food on the brain you can check out Fernando Gomez-Pinilla’s recent article in Nature Reviews Neuroscience (reference below). Here is an overview of the state off the research.

Several components of diet seem to have a positive effect on brain function.

Omega-3 fatty acids

These acids are normal constituents of cell membranes and are essential for normal brain function. Omega-3 fatty acids can be found in fish (salmon), kiwi, and walnuts. Docosahexaenoic acid, or DHA, is the most abundant omega-3 fatty acid in cell membranes in the brain. The human body produces DHA but not enough. So we are dependent on the DHA that we get from what we eat.

A randomized double-blind controlled trial (which means seriously conducted scientific study) is currently looking at the effect of taking omega-3 fatty acids on children’s performance at school in England. Preliminary results (Portwood, 2006) suggest that Continue Reading »

I apologize for the long delay in getting back to this column but I have a good excuse. We just recently had a baby, and boy, that takes care right there of the physical exercise need. Between carrying the baby upstairs and downstairs, running to get the baby, getting out of the bed and picking the baby up and putting the baby down a couple of times a night no you need not worry about getting your daily exercise dose in…Now, the majority of the answers to my post on the brain virtues of physical exercise suggests that most people think that the brain benefits of physical exercise are mostly to be understood as complementary effects of a healthy life style.

Is this correct? In my post today I will attempt to answer this question.

First, while generally healthier people seem to have healthier brains, the physical exercise effect on the brain seems to be independent of other things. One of the most important development in neuroscience was when the official dogma claiming that there was no neurogenesis (production of new brain cells) in the adult brain was toppled. Now we know that the brain is “plastic” meaning that, under the right circumstances, the brain can change Continue Reading »

After about age 50, most people begin to experience a decline in memory capability. Why is that? One obvious answer is that the small arteries of the brain begin to clog up, often as a result of a lifetime of eating the wrong things and a lack of exercise. If that lifetime has been stressful, many neurons may have been killed by stress hormones. Given the most recent scientific literature, reviewed in my book Thank You, Brain, For All You Remember. What You Forgot Was My Fault, dead neurons can’t be replaced, except in the hippocampus, which is fortunate for memory because the hippocampus is essential for making certain kinds of memories permanent. Another cause is incipient Alzheimer’s disease; autopsies show that many people have the lesions of the disease but have never shown symptoms, presumably because a lifetime of exceptional mental activity has built up a “cognitive reserve.”

So is there anything you can do about it besides exercise like crazy, eat healthy foods that you don’t like all that much, pop your statin pills, and take up yoga?

Yes. In short: focus, focus, focus.

Changing thinking styles can help. Research shows that Continue Reading »

My natural rhythms are in cycle with the school calendar. January 1st takes a back seat to my new year, which gets ushered in with the month of September when there is crispness in the air that gradually shakes off the slower, more relaxed pace of summer.Conveniently, my career in teaching meshes with my natural cyclical year. And as this year draws to a close, I am re-energized by the pace of summer, knowing that anything may pop in to my mind as I engage in activities not directly related to school. But before that happens, I’d like to reflect on this past year, in particular as it was my first year of blogging about the brain.

My interest in the brain stems from wanting to better understand both how to make school more palatable for students, and professional development more meaningful for faculty. To that end, I began my Neurons Firing blog in April, 2007, have been doing a lot of reading, and been attending workshops and conferences, including Learning & the Brain.

If you agree that our brains are designed for learning, then Continue Reading »