SharpBrains

Not a day goes by without a significant depression-related announcement. Yesterday, one could read that Older Women More Likely to Suffer Depression (than Older Men; in the Washington Post). Today, we see that St. Jude Starting Trial On Brain Stimulation For Depression (CNN). A few days ago, Blue Cross of California Launched Maternity Depression Program (press release).

Time to step back and ask ourselves questions such as, "What is going On", "What is Depression", "What Treatments Work, and What is the Latest Research". Fortunately, thanks to our collaboration with Greater Good Magazine, Jill Suttie offers a fascinating answers to those questions-and more. Enjoy.

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Closing the Circuit

Helen Mayberg's research could revolutionize depression treatment.

--- By Jill Suttie.

At some point in their lives, 5 to 12 percent of American men and 10-25 percent of women will suffer an episode of depression, making it the most commonly diagnosed mental disorder today. Unlike normal sadness, which passes with time, depression feels unstoppable and causes people to lose interest in nearly all activities. Because it affects a person's ability to eat, sleep, work, and function normally, it exacts a huge cost on the economy, estimated at $30 billion dollars annually. The cost in human suffering cannot be measured.

Millions of people diagnosed with depression turn to medication as a treatment, and many of the most popular Continue Reading »

Last week, the US Car Care Council released a list of tips on how to take care of your car and “save big money at the pump in 2008.”

You may not have paid much attention to this announcement. Yes, it’s important to save gas these days; but, it’s not big news that good maintenance habits will improve the performance of a car, and extend its life.

If we can all agree on the importance of maintaining our cars that get us around town, what about maintaining our brains sitting behind the wheel?

A spate of recent news coverage on brain fitness and “brain training” has missed an important constituency: younger people. Recent advancements in brain science have as tremendous implications for teenagers and adults of all ages as they do for seniors.

In a recent conversation with neuroscientist Yaakov Stern of Columbia University, he related how surprised he was when, years ago, a reporter from Seventeen magazine requested an interview. The reporter told Dr. Stern that he wanted to write an article to motivate kids to stay in school and not to drop out, in order to start building their Cognitive Reserve early and age more gracefully.

What is the Cognitive Reserve? Continue Reading »

Over the last months, thanks to the traffic growth of SharpBrains.com (over 100,000 unique visitors per month these days, THANK YOU for visiting today and please come back!), a number of proactive book agents, publishers and authors have contacted us to inform us of their latest brain-related books. We have taken a look at many books, wrote reviews of The Dana Guide to Brain Health book review and Best of the Brain from Scientific American, and interviewed scientists such as Judith Beck, Robert Emmons and James Zull.

Now we are launching a new Author Speaks Series to provide a platform for leading scientists and experts writing high-quality brain-related books to reach a wide audience. We are honored to start the series with an article by Larry McCleary, M.D, former acting Chief of Pediatric Neurosurgery at Denver Children's Hospital, and author of The Brain Trust Program: A Scientifically Based Three-Part Plan to Improve Memory, Elevate Mood, Enhance Attention, Alleviate Migraine and Menopausal Symptoms, and Boost Mental Energy (Perigee Trade, 2007).

Without further ado, let's enjoy Dr. McCleary's article:

Brain Evolution and Why it is Meaningful Today to Improve Our Brain Health

You may feel overwhelmed by the stream of seemingly contradictory suggestions regarding the best way to maintain mental clarity as you age. Based on an analysis of seminal factors in the development of modern brain anatomy, I believe it is possible to make some very compelling recommendations for growing big brains, enhancing their function, and making them resistant to the aging process. These may be loosely categorized as factors pertaining to the mental or physical attributes of the brain. Although they are not truly independent entities, such a conceptualization provides a basis for the generation of brain healthy prescriptions. Diet, physical exercise, and stress reduction enhance neuronal resilience. Sleep and mental stimulation are vital for cognitive ability, learning, and memory.

Diet: Follow a modern shore-based/marine diet including seafood in its most general sense, non-starchy vegetables of all colors, berries, and eggs. Other sources of lean protein containing long-chain omega 3 fatty acids such as free range beef, chicken, bison, or elk are nutritious alternatives.

Physical exercise (Think ‘fight or flight’ activity.): Include all types. Aerobic activities such as swimming, bicycling, walking, or hiking for promotion of vascular health and weight control; resistance training for promotion of neurotrophic factors, naturally occurring compounds that make brain cells more resistant to aging, such as IGF-1 (Insulin-like growth factor-1) and BDNF (Brain-derived neurotrophic factor); and balance, coordination, and agility training such as ping-pong, balance beam, trampoline, and jumping rope to enhance cognitive speed and motor skills.

Stress Control: From an evolutionary perspective, stressors (such as meeting a cave bear) and intense physical activity (running or fighting) were brief in duration and usually occurred together. Modern stressors (psychological or emotional stress) tend to be unremitting and are generally uncoupled from the physical (fight or flight) component, meaning stress develops without any associated physical activity. Such intense physical pursuits are now called exercise. Not surprisingly, exercise is a perfect physiologic antidote for stress due to its beneficial impact on cortisol (the ‘stress’ hormone) and blood pressure and should be incorporated into any program of stress reduction.

Adequate sleep: The body needs rest, but the brain requires sleep. Acute or chronic sleep deprivation causes devastating short and long-term consequences to brain anatomy (synaptic loss) and function (memory and learning difficulties). Off-line information processing and memory consolidation are additional sleep-related benefits.

Mental stimulation: Brain-training, a cognitively challenging lifestyle, novelty, and socialization are vital for the promotion of neuronal plasticity and neurogenesis (the formation of new nerve cells and neuronal connections), the enhancement of specific brain functions such as memory, and the development of cognitive reserve –additional mental processing potential that may be brought online when needed.

The combination of these recommendations, each of which was instrumental in the transformation from primitive to modern nervous systems, provides a template for the most logical approach for enhancing mental function and resisting neurodegeneration as we travel through life.

The Evolutionary Rationale

The human brain clearly has the genetic potential for dramatic expansion. This was illustrated about Continue Reading »

A misconception we encounter often is that "memory" is the only, or most important, "thing" that our brains do. And the only one we need to care for.

We have a variety of cognitive abilities, from attention to processing speed to problem-solving to emotional self-regulation to, yes, memory. (And more). Even memory is not one whole thing, but has different types and processes: working memory vs. long-term, auditory vs. visual, events vs. facts vs. skills.

I say this in the context of this article and video you may already have seen, where a young chimp displays amazing visual working memory capability, beating humans.

- Read insightful blog post here. Quote

"This study shows that chimps can memorize at a glance the numerals presented Continue Reading »

(Dear reader: Here you have a little gift to continue the Thanksgiving spirit. Enjoy the interview, and thank you for visiting our site.)

Prof. Robert Emmons studies gratitude for a living as Professor of Psychology at UC Davis and is Editor-In-Chief of the Journal of Positive Psychology. He has just published Thanks: How the New Science of Gratitude Can Make You Happier, an interdisciplinary book that provides a research-based synthesis of the topic as well as practical suggestions.

Alvaro Fernandez: Welcome. Prof. Emmons, could you please provide us an overview of the Positive Psychology field so we understand the context for your research?

Robert Emmons: Sure. Martin Seligman and colleagues launched what was called “positive psychology” in the late 90s as an antidote to the traditional nearly exclusive emphasis of “negative psychology” focused on fixing problems like trauma, addiction, and stress. We want to balance our focus and be able to help everyone, including high-functioning individuals. A number of researchers were investigating the field since the late 80s, but Seligman provided a new umbrella, a new category, with credibility, organized networks and funding opportunities for the whole field.

And where does your own research fit into this overall picture?

I have been researching gratitude for almost 10 years. Gratitude is a positive emotion that has traditionally been the realm of humanists and philosophers, and only recently the subject of a more scientific approach. We study gratitude not as a merely academic discipline, but as a practical framework to better functioning in life by taking control of happiness levels and practicing the skill of emotional self-regulation.

What are the 3 key messages that you would like readers to take away from your book?

First, the practice of gratitude can increase happiness levels by around 25%. Second, this is not hard to achieve - a few hours writing a gratitude journal over 3 weeks can create an effect that lasts 6 months if not more. Third, that cultivating gratitude brings other health effects, such as longer and better quality sleep time.

What are some ways to practice gratitude, and what benefits could we expect? Please refer to your 2003 paper in the Journal of Personality and Social Psychology, where I found fascinating quotes such as that “The ability to notice, appreciate, and savior the elements of one’s life has been viewed as a crucial element of well-being.”

The most common method we use in our research is to ask people to keep a “Gratitude Journal” where you write something you feel grateful for. Doing so 4 times a week, for as little as 3 weeks, is often enough to create a meaningful difference in one’s level of happiness. Another exercise is to write a “Gratitude Letter” to a person who has exerted a positive influence on one’s life but whom we have not properly thanked in the past, and then to meet that person and read the letter to them face to face.

The benefits seem to be very similar using both methods in terms of enhanced happiness, health and wellbeing. Most of the outcomes are self-reported, but there is an increasing emphasis on measuring objective data such as cortisol and stress levels, heart rate variability, and even brain activation patterns. The work of Richard Davidson is exemplary in that respect, showing how mindfulness practice can rewire some activation patterns in Continue Reading »

Who has not heard "Use It or Lose It". Now, what is "It"? Last week I gave a talk at the Italian Consulate in San Francisco, and one of the areas attendants seemed to enjoy the most was learning what our brains are and how they work, peaking into the "black box" of our minds. Without understanding at least the basics, how can we make good decisions about our own brain health and fitness?

Let's review at a glance:

The brain is composed of 3 "brains" or main sub-systems, each named after the evolutionary moment in which the sub-system is believed to have appeared. Continue Reading »

Here is question 17 of 25 from Brain Fitness 101: Answers to Your Top 25 Questions.

Question:
Are there herbal and vitamin supplements that will protect my memory?

Key Points:

• Omega-3 and omega-6 fatty acids found in cold-water fish may be helpful to long term brain health.
• Folic acid may also be helpful to both cognitive function and hearing.
• Ginkgo biloba and DHEA do not appear to help your brain.
• There is still more research to be done and never dismiss the placebo effect!

Answer:
Continue Reading »