I  am very excited to pre-announce a col­lab­o­ra­tion with the Amer­i­can Soci­ety on Aging (ASA) to co-produce a Brain Health event, themed “New Tools, New Part­ner­ships”, to take place in Oak­land, CA, on Sep­tem­ber 11th. Read the rest of this entry »

Think about this: How can any­one take care of his or her brain when every week brings a new bar­rage of arti­cles and stud­ies which seem to con­tra­dict each other?

Do sup­ple­ments improve mem­ory? Do you need both phys­i­cal and men­tal exer­cise or is one of them enough? Which brain train­ing approach, if any, is worth one’s time and money?

We tried to address these ques­tions, and many oth­ers, in our recent book, The Sharp­Brains Guide to Brain Fit­ness (182 pages, $24.95), that we pre­sented at Games for Health Con­fer­ence last week. The book is the result of over two years of exten­sive research includ­ing more than a hun­dred inter­views with sci­en­tists, pro­fes­sion­als and con­sumers, and a deep review of the sci­en­tific lit­er­a­ture, led by neu­ropsy­chol­o­gist Elkhonon Gold­berg and myself with the help of cog­ni­tive sci­en­tist Pas­cale Mich­e­lon. As we wrote in the Intro­duc­tion, what we wanted to do first of all was to debunks these 10 myths on brain health and brain training:

Myth 1. Genes deter­mine the fate of our brains.
Facts: Life­long neu­ro­plas­tic­ity allows our lifestyles and actions to play a mean­ing­ful role in how our brains phys­i­cally evolve, espe­cially given longer life expectancy.

Myth 2. Aging means auto­matic decline.
Facts: There is noth­ing inher­ently fixed in the pre­cise tra­jec­tory of how brain func­tions evolve as we age.

Myth 3. Med­ica­tion is the main hope for cog­ni­tive enhance­ment.
Facts: Non-invasive inter­ven­tions can have com­pa­ra­ble and more durable effects, side effect-free.

Myth 4. We will soon have a Magic Pill or Gen­eral Solu­tion to solve all our cog­ni­tive chal­lenges.
Facts: A multi-pronged approach is rec­om­mended, cen­tered around nutri­tion, stress man­age­ment, and both phys­i­cal and men­tal exercise.

Myth 5. There is only one “Use It or Lose it”.
Facts: The brain is com­posed of a num­ber of spe­cial­ized units. Our life and pro­duc­tiv­ity depend on a vari­ety of brain func­tions, not just one.

Myth 6. All brain activ­i­ties or exer­cises are equal.
Facts: Var­ied and tar­geted exer­cises are the nec­es­sary ingre­di­ents in brain train­ing so that a wide range of brain func­tions can be stimulated.

Myth 7. There is only one way to train your brain.
Facts: Brain func­tions can be impacted in a num­ber of ways: through med­i­ta­tion, cog­ni­tive ther­apy, cog­ni­tive training.

Myth 8. We all have some­thing called “Brain Age”.
Facts: Brain age is a fic­tion. No two indi­vid­u­als have the same brain or expres­sion of brain functions.

Myth 9. That “brain age”‚ can be reversed by 10, 20, 30 years.
Facts: Brain train­ing can improve spe­cific brain func­tions, but, with research avail­able today, can­not be said to roll back one “brain age”‚ by a num­ber of years.

Myth 10. All human brains need the same brain train­ing.
Facts: As in phys­i­cal fit­ness, users must ask them­selves: What func­tions do I need to improve on? In what time­frame? What is my budget?

Do you have other myths in mind you would like  us to address?

We have started to receive great feed­back from the health­care com­mu­nity, such as this email from a neu­ro­sur­geon in Texas:

“I really like the book, it is com­pre­hen­sive with­out being too tech­ni­cal. I have rec­om­mended it to sev­eral patients. There are some other books that I expected would be greeted with enthu­si­asm, but were too com­plex for most of my patients. I think this book is right in the sweet spot”.

A short, sweet, enter­tain­ing read of a com­plex topic, with timely (writ­ten in 1/09) reviews of 21 top tech­nol­ogy prod­ucts, as well as informed and expert pre­dic­tions of where this bur­geon­ing brain-fitness field is headed. More impor­tantly, after you read it, you’ll have a good, detailed sense of where you, per­son­ally, can act to improve your own couch-potato brain — and how to keep it fit and flex­i­ble your whole life. The Sharp­Brains Guide To Brain Fit­ness reminds of us all why books (and not just googling a topic) can be well worth your time and money. Two Stetho­scopes Up — check it out. life.”

And this great book review by an Internist Physi­cian and Robert Wood John­son Foun­da­tion Fel­low, titled Is Your Brain A Couch Potato?:

Doc Gur­ley, book review for SFGate.com (06/08/09)

The book:  The Sharp­Brains Guide to Brain Fit­ness (avail­able via Amazon.com Here, review copies avail­able upon request).

Descrip­tion: While most of us have heard the phrase “use it or lose it,” very few under­stand what it means, or how to prop­erly ‚“use it”‚¬ in order to main­tain brain func­tion and fit­ness. The Sharp­Brains Guide to Brain Fit­ness is an invalu­able guide that helps read­ers nav­i­gate grow­ing brain research and iden­tify the lifestyle fac­tors and prod­ucts that con­tribute to brain health and fit­ness. By gath­er­ing insights from eigh­teen of the world’s top sci­en­tists and offer­ing tools and detailed descrip­tions of over twenty prod­ucts, this book is an essen­tial guide to the field of brain fit­ness, neu­ro­plas­tic­ity and cog­ni­tive health. An acces­si­ble and thought-provoking read, The Sharp­Brains Guide to Brain Fit­ness edu­cates life­long learn­ers and pro­fes­sion­als in health­care, edu­ca­tion, busi­ness, etc., on emerg­ing trends and fore­casts of what the future will hold.

Prod­ucts Reviewed (we reviewed sci­en­tific stud­ies pub­lished before Jan­u­ary 2009, when the man­u­script text was closed):

– Over­all brain main­te­nance: Brain Age series (Nin­tendo), Brain­Ware Safari (Learn­ing Enhance­ment Cor­po­ra­tion), FitBrains.com (Viv­ity Labs), Happy-Neuron.com (Sci­en­tific Brain Train­ing), Lumosity.com (Lumos Labs), Mind­Fit (Cog­niFit), (m)Power (Dakim)

– Tar­geted brain work­out: Clas­sic and InSight (Posit Sci­ence), Work­ing Mem­ory Train­ing JM and RM (Cogmed), Dri­ve­Fit (Cog­niFit), Earo­bics (Houghton Mif­flin), Fast For­Word (Sci­en­tific Learn­ing), Intel­li­Gym (Applied Cog­ni­tive Engi­neer­ing), Vision Rest­pra­tion Ther­apy (NovaVision)

– Emo­tional self-regulation: emWave PC and Per­sonal Stress Reliever (Heart­Math), Jour­ney to the Wild Divine (Wild Divine), RES­PeR­ATE (Inter­Cure), StressEraser (Helicor)

This is a par­tial list of the lit­er­a­ture we reviewed dur­ing the research phase of our new book, The Sharp­Brains Guide to Brain Fit­ness.  We know many friends of Sharp­Brains are researchers, health­care pro­fes­sion­als, graduate/ Ph.D. stu­dents, who want have direct access to the ref­er­ences (per­haps PubMed should pro­mote itself as a never end­ing source of men­tal stim­u­la­tion?), so here you have this list, orga­nized by rel­e­vant chap­ter. Please note that the list below appears in the book — whose man­u­script we had to close in Jan­u­ary 2009.

Intro­duc­tion

Basak, C. et al. (2008). Can train­ing in a real-time strat­egy video game atten­u­ate cog­ni­tive decline in older adults? Psy­chol­ogy and Aging.
Beg­ley, S. (2007). Train your mind, change your brain: How a new sci­ence reveals our extra­or­di­nary poten­tial to trans­form our­selves. Bal­lan­tine Books.
DeKosky, S. T., et al. (2008). Ginkgo biloba for pre­ven­tion of demen­tia: a ran­dom­ized con­trolled trial. Jour­nal of the Amer­i­can Med­ical Asso­ci­a­tion, 300, 2253–2262.
Doidge, N. (2007). The Brain that changes itself: Sto­ries of per­sonal tri­umph from the fron­tiers of brain sci­ence. Viking Adult.

Chap­ter 1. The Brain and Brain Fit­ness 101

Bunge, S. A., & Wright, S. B. (2007). Neu­rode­vel­op­men­tal changes in work­ing mem­ory and cog­ni­tive con­trol. Cur­rent Opin­ion In Neu­ro­bi­ol­ogy, 17(2), 243–50.
Dama­sio, A. (1995). Descartes error: Emo­tion, rea­son, and the human brain. Pen­guin Press.
David Kolb, D. (1983). Expe­ri­en­tial learn­ing: Expe­ri­ence as the source of learn­ing and devel­op­ment. FT Press.
Dra­gan­ski, B., Gaser, C., Kem­per­mann, G., Kuhn, H. G., Win­kler, J., Buchel, C., & May A. (2006). Tem­po­ral and spa­tial dynam­ics of brain struc­ture changes dur­ing exten­sive learn­ing. The Jour­nal of Neu­ro­science, 261231, 6314–6317.
Gage, F. H., Kem­per­mann, G., & Song, H. (2007). Adult Neu­ro­ge­n­e­sis. Cold Spring Har­bor Lab­o­ra­tory Press, NY.
Gard­ner, H. (1983). Frames of Mind: The the­ory of mul­ti­ple intel­li­gences. New York: Basic Books.
Gaser, C. & Schlaug, G. (2003). Brain struc­tures dif­fer between musi­cians and non-musicians. The Jour­nal of Neu­ro­science, 23, 9240–9245. Read the rest of this entry »

The Longevity Div­i­dend is a the­ory that says we hope to inter­vene sci­en­tif­i­cally to slow the aging process, which will also delay the onset of age-related dis­eases. Delay­ing aging just seven years would slash rates of con­di­tions like can­cer, dia­betes, Alzheimer’s dis­ease and heart dis­ease in half. That’s the longevity part.

The div­i­dend comes from the social, eco­nomic, and health bonuses that would then be avail­able to spend on schools, energy, jobs, infra­struc­ture tril­lions of dol­lars that today we spend on health­care ser­vices. In fact, at the rate we’re going, by the year 2020 one out of every $5 spent in this coun­try will be spent on health­care. Obvi­ously, some­thing has to change.

Enter the Longevity Div­i­dend. The Longevity Div­i­dend doesn’t sug­gest that we live longer; instead, it calls for liv­ing bet­ter. The idea is that if we use sci­ence to increase healthspan, not lifes­pan. In other words, tomor­rows 50-year-old would have the health pro­file of a 43-year-old.

It might sound like sci­ence fic­tion, but, in fact, it’s quite pos­si­ble. We’re already doing it in some ani­mal mod­els using genetic and dietary inter­ven­tions, tech­niques related to what sci­en­tists call “the biol­ogy of aging.”

Get­ting there in humans, how­ever, means embrac­ing an entirely new approach to our think­ing about dis­ease and aging, and how we con­duct sci­en­tific research into the two.

Get­ting Sci­en­tists’ Attention

A group of emi­nent researchers first pro­posed the Longevity Div­i­dend in a 2006 arti­cle pub­lished in The Sci­en­tist. The authors, S. Jay Olshan­sky, PhD, pro­fes­sor of epi­demi­ol­ogy and bio­sta­t­ics at the Uni­ver­sity of Illi­nois in Chicago, Daniel P. Perry, exec­u­tive direc­tor of the Alliance for Aging Research in Wash­ing­ton, DC, Richard A. Miller, MD, PhD, pro­fes­sor of pathol­ogy at the Uni­ver­sity of Michi­gan in Ann Arbor, and Robert N. But­ler, MD, pres­i­dent and CEO of the Inter­na­tional Longevity Cen­ter in New York, intended their essay to be a “gen­eral state­ment to sci­en­tists about the need for a par­a­digm shift in the way we think about aging and disease.

The researchers also met with U.S. sen­a­tors who served on the Sen­ate com­mit­tee that over­saw the bud­get for the National Insti­tutes of Health (NIH). “We told them we believed Read the rest of this entry »

After many many months of men­tal stim­u­la­tion, phys­i­cal exer­cise and the cer­tain need for stress man­age­ment… we have just announced the release of the The State of the Brain Fit­ness Soft­ware Mar­ket 2009 report, our sec­ond annual com­pre­hen­sive mar­ket analy­sis of the US mar­ket for com­put­er­ized cog­ni­tive assess­ment and train­ing tools. In this report we esti­mate the size of the US brain fit­ness soft­ware mar­ket at $265M in 2008, up from $225M in 2007 (18% annual growth), and from $100m in 2005. Two seg­ments fuelled the mar­ket growth from 2007 to 2008: con­sumers (grew from $80m to $95m) and health­care & insur­ance providers (grew from $65m to $80m).

The 150-page report finds promis­ing research and ini­tia­tives to drive sig­nif­i­cant growth, com­bined with increased con­sumer con­fu­sion given aggres­sive mar­ket­ing claims and lack of edu­ca­tion and stan­dards. The report includes:
– The com­plete results of an exclu­sive Jan­u­ary 2009 Sur­vey with 2,000+ respon­dents
– A pro­pri­etary Mar­ket & Research Momen­tum Matrix to cat­e­go­rize 21 key ven­dors into four cat­e­gories
– 10 Research Exec­u­tive Briefs writ­ten by lead­ing sci­en­tists at promi­nent research labs
– An analy­sis of the level of clin­i­cal val­i­da­tion per prod­uct and cog­ni­tive domain

Top 10 High­lights from the report:

1) Con­sumers, seniors, com­mu­ni­ties and insur­ance providers drove year on year sus­tained growth, from $225m in 2007 to $265m in 2008. Rev­enues may reach between $1 bil­lion to $5 bil­lion by 2015, depend­ing on how impor­tant prob­lems (Pub­lic Aware­ness, Nav­i­gat­ing Claims, Research, Health Cul­ture, Lack of Assess­ment) are addressed.

2) Increased inter­est and con­fu­sion: 61% of respon­dents Strongly Agree with the state­ment Address­ing cog­ni­tive and brain health should be a health­care pri­or­ity. But, 65% Agree/Strongly Agree. I don’t really know what to expect from prod­ucts mak­ing brain claims.

3) Invest­ment in R&D seeds future growth: Land­mark invest­ments by insur­ance providers and government-funded research insti­tutes test­ing new brain fit­ness appli­ca­tions planted new seeds for future growth.

4) Becom­ing stan­dard in res­i­den­tial facil­i­ties: Over 700 res­i­den­tial facil­i­ties mostly Inde­pen­dent and Assisted Liv­ing facil­i­ties and CCRCs have installed com­put­er­ized cog­ni­tive train­ing programs.

5) Cus­tomer sat­is­fac­tion: Con­sumers seem more sat­is­fied with computer-based prod­ucts than paper-based options. But, sat­is­fac­tion dif­fers by prod­uct. When asked I got real value for my money, results were as fol­lows: Lumosity.com (65% Agree), Puz­zle Books (60%), Posit Sci­ence (52%), Nin­tendo (51%) agreed. Posit Sci­ence (53% Agree) and Lumosity.com (51%) do bet­ter than Puz­zle Books (39%) and Nin­tendo (38%) at I have seen the results I wanted.

6) Assess­ments: Increas­ing adop­tion of computer-based cog­ni­tive assess­ments to base­line and track cog­ni­tive func­tions over time in mil­i­tary, sports, and clin­i­cal con­texts. The Alzheimer’s Foun­da­tion of Amer­ica now advo­cates for wide­spread cog­ni­tive screen­ings after 65–75.

7) Spe­cific com­put­er­ized cog­ni­tive train­ing and videogames have been shown to improve brain func­tions, but the key ques­tions are, Which ones, and Who needs what when?

Aggres­sive mar­ket­ing claims are cre­at­ing con­fu­sion and skep­ti­cism, result­ing in a dis­tract­ing con­tro­versy between two mis­lead­ing extremes: (a) buy­ing prod­uct XYZ can reju­ve­nate your brain Y years or (b) those prod­ucts don’t work; just do one more cross­word puz­zle. The upcom­ing book The Sharp­Brains Guide to Brain Fit­ness aims to help con­sumers nav­i­gate these claims.

9) Devel­op­ers can be clas­si­fied into four groups, based on a pro­pri­etary Mar­ket and Research Momen­tum Matrix: Sharp­Brains finds 4 Lead­ers, 8 High Poten­tials, 3 Cross­words 2.0, and 6 Wait & See companies.

10) Increased dif­fer­en­ti­a­tion: Lead­ing com­pa­nies are bet­ter defin­ing their value propo­si­tion and dis­tri­b­u­tion chan­nels to reach spe­cific seg­ments such as retire­ment com­mu­ni­ties, schools, or health­care providers.

Lead­ing researchers pre­pared 10 Research Exec­u­tive Briefs:
- Dr. Joshua Stein­er­man (Einstein-Monteore): Neu­ro­pro­tec­tion via cog­ni­tive activ­i­ties
– Dr. Jerri Edwards (South Florida): Assess­ments of dri­ving fit­ness
– Dr. Susanne Jaeggi and Dr. Mar­tin Buschkuehl (Bern, Michi­gan): Work­ing mem­ory train­ing and  intel­li­gence
– Dr. Torkel Kling­berg (Karolin­ska): Work­ing mem­ory train­ing, dopamine, and math
– Dr. Liz Zelin­ski (UC Davis): Audi­tory pro­cess­ing train­ing
– Dr. David Vance (UAB): Speed-of-processing train­ing
– Dr. Jerri Edwards (South Florida): Cog­ni­tive train­ing for healthy aging
– Dr. Daphne Bave­lier & Dr. Shawn Green (Rochester): Action videogames and atten­tional skills
– Dr. Arthur Kramer (Illi­nois): Strat­egy videogames and exec­u­tive func­tions
– Dr. Yaakov Stern (Colum­bia): The cog­ni­tive reserve and neu­roimag­ing
– Dr. David Rabiner (Duke): Objec­tive assess­ments for ADHD

Table of Contents

Edi­to­r­ial
Exec­u­tive Sum­mary
Chap­ter 1. Bird-Eye View of the Grow­ing Field
Chap­ter 2. Mar­ket Sur­vey on Beliefs, Atti­tudes, Pur­chase Habits
Chap­ter 3. The Emerg­ing Com­pet­i­tive Land­scape
Chap­ter 4. The Sci­ence for Brain Fit­ness and Cog­ni­tive Health
Chap­ter 5. Con­sumers  Adopt­ing Cross­words 2.0?
Chap­ter 6: Health­care and Insur­ance Providers — A Cul­ture of Cog­ni­tive Health
Chap­ter 7: K12 School Sys­tems– Ready for Change?
Chap­ter 8: Mil­i­tary, Sports Teams, Com­pa­nies,  Brain-Performance Link
Chap­ter 9: Future Direc­tions‚ Pro­jec­tions and Bottlenecks

Com­pa­nies pro­filed include: Advanced Brain Tech­nolo­gies, Applied Cog­ni­tive Engi­neer­ing, Brain Cen­ter Amer­ica, Brain Resource, CNS Vital Signs, Cogmed, Cogstate, Cog­niFit, Cog­ni­tive Drug Research, Dakim, Houghton Mif­flin, Learn­ing Enhance­ment Cor­po­ra­tion, Learn­ingRx, Lumos Labs, Mar­bles: The Brain Store, Nin­tendo, NovaV­i­sion, Posit Sci­ence, Sci­en­tific Brain Train­ing, Sci­en­tific Learn­ing, Trans­An­a­lyt­ics, vibrant­Brains, Vig­or­ous Mind, Viv­ity Labs.

More on the report by click­ing on The State of the Brain Fit­ness Soft­ware Mar­ket 2009.

(Editor’s Note: I recently came across an excel­lent book and resource, The Alzheimer’s Action Plan: The Experts’ Guide to the Best Diag­no­sis and Treat­ment for Mem­ory Prob­lems, just released in paper­back. Dr. Murali Doraiswamy, one of the authors and lead­ing Alzheimer’s expert, kindly helped us cre­ate a 2-part arti­cle series to share with Sharp­Brains read­ers advice on a very impor­tant ques­tion, “How can we help the pub­lic at large to dis­tin­guish Alzheimer’s Dis­ease from nor­mal aging — so that an inter­est in early iden­ti­fi­ca­tion doesn’t trans­late into unneeded wor­ries?” What fol­lows is an excerpt from the book, pages 3–8).

—

As it turns out, Jane did not have Alzheimer’s. She con­sulted a doc­tor, who, in doc­s­peak, told her that the pas­sage of time (get­ting older) had taken a slight toll on her once-superquick mem­ory. She was slow­ing down a lit­tle, and if she relaxed, the name or date or other bit of infor­ma­tion she needed would come to her soon enough. She was still good at her job and home life. She had sim­ply joined the ranks of the wor­ried well.

Nor­mal brain aging, begin­ning as early as the for­ties in some peo­ple, may include:

• Tak­ing longer to learn or remem­ber information
• Hav­ing dif­fi­culty pay­ing atten­tion or con­cen­trat­ing in the midst of distractions
• For­get­ting such basics as an anniver­sary or the names of friends
• Need­ing more reminders or mem­ory cues, such as promi­nent appoint­ment cal­en­dars, reminder notes, a phone with a well­stocked speed dial

Although they may need some assis­tance, older peo­ple with­out a men­tal dis­or­der retain their abil­ity to do their errands, han­dle money, find their way to famil­iar areas, and behave appropriately.

How does this com­pare to a per­son with Alzheimer’s? When Alzheimer’s slows the brain’s machin­ery, peo­ple begin to lose their abil­ity to Read the rest of this entry »

There’s such a flood of very sig­nif­i­cant research stud­ies, edu­ca­tional resources and arti­cles related to brain health, it’s hard to keep track — even for us!

Let me intro­duce and quote some of the top Brain Health Stud­ies, Arti­cles and Resources pub­lished in March:

1) Cog­ni­tive Decline Begins In Late 20s, Study Sug­gests (Sci­ence Daily)

- “These pat­terns sug­gest that some types of men­tal flex­i­bil­ity decrease rel­a­tively early in adult­hood, but that how much knowl­edge one has, and the effec­tive­ness of inte­grat­ing it with one’s abil­i­ties, may increase through­out all of adult­hood if there are no patho­log­i­cal dis­eases,” Salt­house said.

- How­ever, Salt­house points out that there is a great deal of vari­ance from per­son to person

2) Cere­brum 2009: Emerg­ing Ideas in Brain Sci­ence — new book by the Dana Foun­da­tion that “explores the cut­ting edge of brain research and its impli­ca­tions in our every­day lives, in lan­guage under­stand­able to the gen­eral reader.”

A cou­ple of excel­lent chap­ters of direct rel­e­vance to everyone’s brain health are:
– Chap­ter 4: A Road Paved by Rea­son, by Eliz­a­beth Nor­ton Lasley

- Chap­ter 10: Neural Health: Is It Facil­i­tated by Work Force Par­tic­i­pa­tion?, by Denise Park, Ph.D

3) Stay­ing Sharp DVD Pro­gram: “Dr. Jor­dan Graf­man, chief of the Cog­ni­tive Neu­ro­science Sec­tion at the National Insti­tute of Neu­ro­log­i­cal Dis­or­ders and Stroke out­side of Wash­ing­ton, DC, and a mem­ber of the Dana Alliance for Brain Ini­tia­tives, is your guide as we cover what to expect from the aging brain and what we can do to ‘stay sharp.’

For a free DVD of this pro­gram you can con­tact stayingsharp@dana.org. (they say free in their web­site, I don’t know if that includes ship­ping & handling)

4) Dri­vers to be tested on cog­ni­tive abil­ity start­ing at age 75 (Japan Times)

The out­line of a cog­ni­tive test that dri­vers aged 75 or over will be required to take from June when renew­ing their licenses was released Thursday…The test is intended to reduce the num­ber of traf­fic acci­dents involv­ing elderly dri­vers by mea­sur­ing their cog­ni­tive level.

5) Phys­i­cal Fit­ness Improves Spa­tial Mem­ory, Increases Size Of Brain Struc­ture (Sci­ence Daily)

- “Now researchers have found that elderly adults who are more phys­i­cally fit tend to have big­ger hip­pocampi and bet­ter spa­tial mem­ory than those who are less fit.”

6) Brain Train­ers: A Work­out for the Mind (Sci­en­tific Amer­i­can Mind)

“I recently tried out eight of the lat­est brain fit­ness pro­grams, train­ing with each for a week. The pro­grams ranged widely in focus, qual­ity and how fun they were to use. “Like phys­i­cal exer­cise equip­ment, a brain exer­cise pro­gram doesn’t do you any good if you don’t use it, says Andrew J. Carle, direc­tor of the Pro­gram in Assisted Living/Senior Hous­ing Admin­is­tra­tion at George Mason Uni­ver­sity. And peo­ple tend not to use bor­ing equip­ment. “I remem­ber when Nor­dic­Track was the biggest thing out there. Every­one ran out and bought one, and 90 per­cent of them ended up as a clothes rack in the back of your bedroom.

The reporter used: Posit Science’s Brain Fit­ness Pro­gram Clas­sic, Hap­pyNeu­ron, Nin­tendo BrainAge, CogniFit’s MindFit/ Cog­niFit Per­sonal Coach, Lumos­ity, MyBrain­Trainer, Brain­Twister, Cogmed Work­ing Mem­ory Training.

7) The Lat­est in Men­tal Health: Work­ing Out at the ‘Brain Gym’ (Wall Street Journal)

- “Mar­shall Kahn, an 82-year-old fam­ily doc­tor in Fuller­ton, Calif., says he got such a boost from brain exer­cises he started doing at a “Nifty after Fifty” club that he decided to start see­ing patients again part-time. “Doing all the men­tal exer­cise,” he says, “I real­ized I’ve still got it.”

Debate Over Drugs For ADHD Reignites (Wash­ing­ton Post)

- “New data from a large fed­eral study have reignited a debate over the effec­tive­ness of long-term drug treat­ment of chil­dren with hyper­ac­tiv­ity or attention-deficit dis­or­der, and have drawn accu­sa­tions that some mem­bers of the research team have sought to play down evi­dence that med­ica­tions do lit­tle good beyond 24 months.”

- “The study also indi­cated that long-term use of the drugs can stunt children’s growth.”

Adap­tive train­ing leads to sus­tained enhance­ment of poor work­ing mem­ory in chil­dren (Devel­op­men­tal Science)

Abstract: Work­ing mem­ory plays a cru­cial role in sup­port­ing learn­ing, with poor progress in read­ing and math­e­mat­ics char­ac­ter­iz­ing chil­dren with low mem­ory skills. This study inves­ti­gated whether these prob­lems can be over­come by a train­ing pro­gram designed to boost work­ing mem­ory. Chil­dren with low work­ing mem­ory skills were assessed on mea­sures of work­ing mem­ory, IQ and aca­d­e­mic attain­ment before and after train­ing on either adap­tive or non-adaptive ver­sions of the pro­gram. Adap­tive train­ing that taxed work­ing mem­ory to its lim­its was asso­ci­ated with sub­stan­tial and sus­tained gains in work­ing mem­ory, with age-appropriate lev­els achieved by the major­ity of chil­dren. Math­e­mat­i­cal abil­ity also improved sig­nif­i­cantly 6 months fol­low­ing adap­tive train­ing. These find­ings indi­cate that com­mon impair­ments in work­ing mem­ory and asso­ci­ated learn­ing dif­fi­cul­ties may be over­come with this behav­ioral treatment.

9) Brain cor­tex thin­ning linked to inher­ited depres­sion (Los Ange­les Times)

- “On aver­age, peo­ple with a fam­ily his­tory of depres­sion appear to have brains that are 28% thin­ner in the right cor­tex — the out­er­most layer of the brain — than those with no known fam­ily his­tory of the dis­ease. That cor­ti­cal thin­ning, said the researchers, is on a scale sim­i­lar to that seen in patients with Alzheimer’s dis­ease or schizophrenia.”

What started as an aca­d­e­mic dis­pute regard­ing dis­clo­sure of con­flict of inter­est is now snow­balling into the main­stream media, due to the over-reaction by JAMA edi­tors as reported in this Wall Street Jour­nal blog post, JAMA edi­tor calls Critic a “Nobody and a Noth­ing”

In sum­mary, Dr. Jonathan Leo, the “Critic”, dared to draw atten­tion to 2 impor­tant points regard­ing a study com­par­ing the effi­cacy of ther­apy vs. med­ica­tion pub­lished in the Jour­nal of the Amer­i­can Acad­emy of Med­i­cine (JAMA) — one of the most pres­ti­gious sci­en­tific publications:

1) The study results were pre­sented and reported in a biased way, since they favored one spe­cific inter­ven­tion, a drug, while ignor­ing another one, therapy-based, that had equally sta­tis­ti­cally sig­nif­i­cant effects.

2) Both the lead author of the study and one of the main experts asked to com­ment on the study in sev­eral media out­lets had undis­closed and unre­ported con­flicts of inter­est. JAMA could have done a 5-minute Google search to iden­tify and report the con­flict of inter­est of the lead author (received a vari­ety of rev­enues from the drugmaker).

Dr. Leo has sum­ma­rized the con­tin­u­ing mat­ter in sev­eral impres­sive let­ters. The 2 main ones, in chrono­log­i­cal order:

Clin­i­cal Tri­als of Ther­apy vs. Med­ica­tion: Even in a Tie, Med­ica­tion Wins(BMJ)

- “Cen­tral to the idea of evidence-based med­i­cine is that the choices made by patients and doc­tors to use a cer­tain treat­ment should at least in part be based on sci­en­tific stud­ies pub­lished in peer reviewed aca­d­e­mic jour­nals. For a patient diag­nosed with Read the rest of this entry »

(Editor’s note: one of the most com­mon ene­mies of get­ting qual­ity cog­ni­tive exer­cise is being on “men­tal autopi­lot”. I recently came across an excel­lent new book, titled The Daily Trad­ing Coach: 101 Lessons for Becom­ing Your Own Trad­ing Psy­chol­o­gist, by trad­ing per­for­mance expert Dr. Brett Steen­barger, which explic­itly calls for address­ing the “men­tal autopi­lot” prob­lem in his Les­son 4. Even for those of us who are not traders, Dr. Steen­barger advice pro­vides excel­lent guid­ance for peak cog­ni­tive per­for­mance. Dr. Steen­barger gra­ciously gave us per­mis­sion to share with you, below, Les­son 4: Change Your Envi­ron­ment, Change Your­self. Enjoy!).

Human beings adapt to their envi­ron­ments. We draw on a range of skills and per­son­al­ity traits to fit into var­i­ous set­tings. That is why we can behave one way in a social set­ting and then seem like a totally dif­fer­ent human being at work. One of the endur­ing attrac­tions of travel is that it takes us out of our native envi­ron­ments and forces us to adapt to new peo­ple, new cul­tures, and new ways. When we make those adap­ta­tions, we dis­cover new facets of our­selves. As we’ll see shortly, dis­crep­ancy is the mother of all change: when we are in the same envi­ron­ments, we tend to draw upon the same, rou­tine modes of thought and behavior.

A few months ago I had an attack of acute appen­dici­tis while stay­ing in a LaGuardia air­port hotel await­ing a return flight to Chicago. When I went to the near­est emer­gency room at Elmhurst Hos­pi­tal out­side Jack­son Heights, Queens, I found that I was seem­ingly the only native Eng­lish speaker in a sea of peo­ple await­ing med­ical care. After some dif­fi­culty attract­ing atten­tion, I was admit­ted to the hos­pi­tal and spent the next sev­eral days of recu­per­a­tion nav­i­gat­ing my way through patients and staff of every con­ceiv­able nation­al­ity. By the end of the expe­ri­ence, I felt at home there. I’ve since stayed at the same air­port hotel and rou­tinely make vis­its into the sur­round­ing neighborhoods—areas I would have never in my wildest dreams ven­tured into pre­vi­ously. In adapt­ing to that envi­ron­ment, I dis­cov­ered hid­den strengths. I also over­came more than a few hid­den prej­u­dices and fears.

The great­est enemy of change is rou­tine. When we lapse into rou­tine and oper­ate on autopi­lot, we are no longer fully and actively con­scious of what we’re doing and why. That is why some of the most fer­tile sit­u­a­tions for per­sonal growth—those that occur within new environments—are those that force us to exit our rou­tines and actively mas­ter unfa­mil­iar challenges.

In famil­iar envi­ron­ments and rou­tines, we oper­ate on autopi­lot. Noth­ing changes.

When you act as your own trad­ing coach, your chal­lenge is to stay fully con­scious, alert to risk and oppor­tu­nity. One of your great­est threats will be the autopi­lot mode in which you act with­out think­ing, with­out full aware­ness of your sit­u­a­tion. If you shift your trad­ing envi­ron­ment, you push your­self to adapt to new sit­u­a­tions: you break rou­tines. If your envi­ron­ment is always the same, you will find your­self grav­i­tat­ing to the same Read the rest of this entry »

If you sub­scribe to our monthly newslet­ter, you may remem­ber we ran a sur­vey in Jan­u­ary. Well, the response rate and the qual­ity of the responses were noth­ing short of spec­tac­u­lar, in many dimen­sions. The responses from over 2,000 par­tic­i­pants (out of 21,000 sub­scribers) rein­force the need for pub­lic aware­ness ini­tia­tives and qual­ity infor­ma­tion to help eval­u­ate and nav­i­gate prod­uct claims.

I have been pre­sent­ing the results from one of the ques­tions (see below), yes­ter­day at the ASA/ NCOA (Amer­i­can Soci­ety on Aging) event, today at IHRSA (Inter­na­tional Health, Rac­quet and Sports­club Asso­ci­a­tion), as part of more com­pre­hen­sive pre­sen­ta­tions of what is going on in the brain fit­ness and cog­ni­tive health field.

An obvi­ous impli­ca­tion for the sur­vey result rein­forces the need for brain-related pub­lic aware­ness cam­paigns such as the ongo­ing Brain Aware­ness Week. Every year, land­mark research find­ings open new oppor­tu­ni­ties to help main­tain life­long cog­ni­tive health and brain fit­ness. The oppor­tu­nity is immense — but we will need to ensure the mar­ket­place matures in a ratio­nal and sus­tain­able man­ner, help­ing con­sumers and pro­fes­sion­als sep­a­rate hope from hype and make informed decisions.

Robin Klaus, Chair­man of Club One Fit­ness Cen­ters (the com­pany is a client, he is an advi­sor), just gave us a nice quote say­ing that “as our pop­u­la­tion ages the fields of phys­i­cal fit­ness and brain fit­ness will nat­u­rally merge and, as this hap­pens, a whole new field of val­ued added ser­vices will emerge for our mem­bers. High qual­ity infor­ma­tional resources such as Sharp­Brains’ are cru­cial to the suc­cess of this merger.”

The Sur­vey: Results to Key Question

Asked, “What is the most impor­tant prob­lem you see in the brain fit­ness field and how do you think it can be solved?” respon­dents iden­ti­fied the fol­low­ing six prob­lems in rank order:

#1: Pub­lic Aware­ness (39%)
– “Get­ting peo­ple to under­stand that hered­ity alone does not decide brain func­tion­ing.“
– “An expec­tant pub­lic will first want to believe that a “mir­a­cle” drug is to be soon avail­able (to pre­vent Alzheimer’s Disease).”

#2: Nav­i­gat­ing Claims (21%)
- “How to sep­a­rate mar­ket­ing hype from stuff that really works?“
– “The lack of stan­dards and clear def­i­n­i­tions is very con­fus­ing, and makes a lot of peo­ple sceptical.”

#3: Research (15%)
– “Deter­min­ing what activ­i­ties are most ben­e­fi­cial to Read the rest of this entry »