Jul 3, 2007 2
Depression, Stress and Dementia
By: admin
Hi! It’s Andreas, the Norwegian MD/PhD intern at SharpBrains.
Last week Alvaro wrote about how people with low stress levels are better able to tolerate age-related changes in the brain. The other side of the coin, as mentioned today in the Wall Street Journal, is that chronic stress is a risk factor of dementia and might be related to harmful stress hormones called glucocorticoids.
So why do we have glucocorticoids? Well, they are steroids produced to help us manage short-term periods of stress. However, long-term release may erode pathways (connetions) between brain cells and can potentially accelerate cognitive decline.
Why is this relevant to all of us? Because depression can be seen as a chronic state of brain stress, and explain why stress management is important. Studies now show that depression may actually damage brain structures responsible for memory. The findings from a study in Archives of General Psychiatry showed patients with a history of depression are more likely to suffer from cognitive problems later in life, such as Alzheimer’s or dementia. As the journalist writes, “In findings that highlight the importance of mood and stress to maintaining a healthy brain, researchers and psychiatrists say that a bout of depression may raise the risks of developing dementia later in life.”
In some cases, patients with untreated depression exhibit an 10% volume reduction of the brain’s memory center Read the rest of this entry »

We are very excited to announce our newly released Brain Fitness for Sharp Brains: Your New New Year Resolution. We wrote it in order to provide an introduction to the concept, science, and practice of brain fitness in plain English, by answering the Top 25 questions we have received over the last four months. Dr. Elkhonon Goldberg, Alvaro Fernandez and myself (Caroline) have been working hard on this.





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