(Editor’s note: this article belongs to the excellent May 2009 special issue on Augmenting Cognition of scientific journal Frontiers in Neuroscience, Volume 3, Issue 1. You can order this issue, for 50 euros, here. Highly recommended for scientists and technical readers interested in the science. This article, an industry overview, is reproduced here with authorization by the Frontiers Research Foundation).

Preparing Society for the Cognitive Age

- By Alvaro Fernandez

Groundbreaking cognitive neuroscience research has occurred over the last 20 years – without parallel growth of consumer awareness and appropriate professional dissemination. “Cognition” remains an elusive concept with unclear implications outside the research community.

Earlier this year, I presented a talk to health care professionals at the New York Academy of Medicine, titled “Brain Fitness Software: Helping Consumers Separate Hope from Hype”. I explained what computerized cognitive assessment and training tools can do (assess/enhance specific cognitive functions), what they cannot do (reduce one’s “brain age”) and the current uncertainties about what they can do (i.e., delay Alzheimer’s symptoms). At the same symposium, Dr. Gary Kennedy, Director of Geriatric Psychiatry at Montefiore Medical Center, provided guidance on why and how to screen for executive function deficits in the context of dementia.

I could perceive two emerging trends at the event: 1) “Augmenting Cognition” research is most commonly framed as a healthcare, often pharmacological topic, with the traditional cognitive bias in medicine of focusing on detection and treatment of disease, 2) In addition, there is a growing interest in non-invasive enhancement options and overall lifestyle issues. Research findings in Augmenting Cognition are only just beginning to reach the mainstream marketplace, mostly through healthcare channels. The opportunity is immense, but we will need to ensure the marketplace matures in a rational and sustainable manner, both through healthcare and non-healthcare channels.

In January 2009, we polled the 21,000 subscribers of SharpBrains’ market research eNewsletter to identify attitudes and behaviors towards the “brain fitness” field (a term we chose in 2006 based on a number of consumer surveys and focus groups to connect with a wider audience). Over 2,000 decision-makers and early adopters responded to the survey.

One of the key questions we asked was, “What is the most important problem you see in the brain fitness field and how do you think it can be solved?”. Some examples of the survey free text answers are quoted here, together with my suggestions.

Most important problems in the brain fitness field

• Public awareness (39%): “To get people to understand that heredity alone does not decide brain functioning”. We need to ramp up efforts to build public awareness and enthusiasm about brain research, including establishing clear links to daily living. We can collaborate with initiatives such as the Dana Foundation’s Brain Awareness Week and use the recent “Neuroscience Core Concepts” materials developed by the Society for Neuroscience to give talks at schools, libraries and workplaces.

• Claims (21%): “The lack of standards and clear definitions is very confusing, and Read the rest of this entry »

Given the whole distracting “controversy” of whether Nintendo Brain Age “works” or not, I have started to use the following “brain teasers” in my talks in order to help the audience gain a more useful perspective of what is going on. They worked great both in the Medicare Readmissions Summit in DC a few weeks ago, and at the Games for Heath Conference last week.

Q: How many soldiers in the US Army have gone through computerized cognitive testing before being deployed, and why?
A: Over 150,000, in order to establish an objective starting baseline and identify potential Post Traumatic Stress Disorder (PTSD) and Traumatic Brain Injury (TBI) problems upon their return.

Q: How big is the ongoing investment by OptumHealth, a division of UnitedHealth Group (UNH), in developing computerized cognitive assessments to inform clinical decision-making?
A: over $6m.

Q: How many Allstate policy-holders over the age of 50 have received a computerized cognitive training program to improve their driving safety?
A: Over 8,000, in the state of Pennsylvania.

Q: How many residential communities are offering computerized cognitive training programs to their residents?
A: Over 700, in the US alone, covering independent and assisted living.

Q: How much money has the Government of Ontario invested in setting up a new Centre for Brain Fitness as part of Baycrest research center in order to develop and commercialize technologies to assess and enhance cognitive functions?
A: $10m, matched with another 10m from local investors.

For more on our Cognitive Health Track at Games for Health Conference last week, see this USA Today article:

More doctor’s prescriptions may include brain games to improve mental acuity

(pretty good overall, but please note that SharpBrains didn’t organize the whole conference, “only” the cognitive health track, which was a lot of stimulating fun. Ben Sawyer and team did overall conference).

Several readers, after enjoying my interview with Lee Woodruff on the Bob Woodruff Foundation and helping Traumatic Brain Injury survivors, asked for the address of the Bob Woodruff Foundation, in order to send a donation via check.

Here is the right address:

Bob Woodruff Foundation
PO Box 955
Bristow, VA  20136

Thank you for your generosity!

Interview with Lee Woodruff:  here

Bob Woodruff Foundation website: here

We have just announced an upcoming webinar to provide a market update:  Top 10 Cognitive Fitness Events of 2008 – A Market Update.

When: Thursday December 11th, from 12:00 to 1:00 pm Pacific Time. The same webinar will be repeated on Thursday December 18th, from 9:00 to 10:00 pm Pacific Time.

The Top 10 Cognitive Fitness Events that will be discussed include:

1) February: Dakim secures a $10.6m investment from Galen Partners. Jack LaLanne becomes spokesperson.
2) April: The Government of Ontario, Canada, invests $10m in Baycrest to develop and commercialize cognitive fitness technologies.
3) April: University of Michigan researchers reveal in the Proceedings of the National Academy of Sciences how computerized working memory training can generalize and improve fluid intelligence in healthy adults.
4) May: Humana unveils Games for Health initiatives, not renewing its agreement with Posit Science.
5) June: The US Army launches a new policy requiring cognitive screenings of all soldiers before deployment (in order to Read the rest of this entry »

As you have probably seen, the Cognitive Health and Brain Fitness field is rapidly evolving, so let me highlight some of the main recent developments affecting the field:

1) Public policy initiatives:
- The Government of Ontario, Canada, announced a $10m investment in Baycrest Research Center to help develop and commercialize brain fitness technologies. This $10m investment was matched with an additional $10m by local investors.
- In the US, The Paul Wellstone and Pete Domenici Mental Health Parity and Addiction Equity Act of 2008 was signed into law, included in the recently-approved economic bailout bill. The passage of this law has significant implications for healthcare providers and technology vendors alike.

2) Computerized Cognitive Assessments Used by the US Military:
The US Army launched a new policy requiring cognitive screenings of all soldiers before deployment (in order to better diagnose potential problems such as PTSD and TBI upon return). ANAM was the selected computerized battery of tests.

3) Venture & Angel Fundraising for Cognitive Training companies:
A number of developers have raised money. CogniFit received $5m (from Milk Capital), Lumos Labs $3m (FirstMark Capital -previously called Pequot Ventures-, Norwest Venture Partners), Scientific Brain Training $1.5m (issued shares), Vivity Labs $1m (undisclosed angel investors), This is, of course, on top of the February $10.6 investment in Dakim (Galen Partners) that we already included in our market report.

4) Major Initiatives by Insurance Companies:
- Allstate launched a large-scale research project to measure impact of Posit Science InSight (visual processing training) on driver safety for adults over 50.
- OptumHealth announced a 3-year, $18m agreement with Brain Resource to offer web-based cognitive assessments as part of clinicians’ decision support systems.
- Humana decided not to renew its agreement with Posit Science to offer Posit’s auditory processing training program to Medicare members.

5) New Research:
- In a significant new study, a team from the University of Michigan published a high-quality paper in the Proceedings of the National Academy of Sciences showing how computerized working memory training can generalize and improve fluid intelligence (one of the domains that tends to decline with age).
- Learning and Teaching Scotland released an internal study showing how Nintendo Brain Training can help children’s math and concentration skills. The study gained significant media attention, despite the fact it hasn’t been published in a respected journal.

Note: This is an excerpt from the 6-Month Market Update we will  release later this month, covering the many important developments that have occurred since we launched the inaugural Brain Fitness Market Report in March this year. This special report will be available exclusively for our Premium Research Sponsors.

You have may have seen a few weeks ago the interview between former US presidential contender John Edwards and reporter Bob Woodruff. All the resulting media coverage centered on Edwards’ declarations. However, there is something much more remarkable that surfaced at that interview: Bob Woodruff’s spectacular recovery.

This is the same reporter who suffered a severe traumatic brain injury when a roadside bomb detonated next to his vehicle in January 29th 2006 as he was covering news developments in Iraq.

Today we are fortunate to interview Lee Woodruff, Bob’s wife and pillar throughout his recovery. Lee and Bob co-wrote the fantastic book In an Instant: A Family’s Journey of Love and Healing.

Alvaro Fernandez: Lee, many thanks for your time. I was amazed reading your book, where you share your journey, and then watching Bob interview John Edwards, the best display I can imagine of his recovery. Can you please summarize for us what Bob -and you- went through since January 2006?

Lee Woodruff: As you know, Bob suffered a life-threatening traumatic brain injury in Iraq. He was promptly taken under military care and underwent a series of surgeries for head injuries, with a joint Army & Air Force neurosurgical team in Iraq, in a US Army Medical Command hospital in Germany, and at Bethesda Naval Hospital, back here in the US.

During this time, spanning around 4 months, he spent 37 days in coma, and his skull had to be surgically rebuilt. The cognitive rehabilitation process started then, at a medical facility closer home.

Can you please explain what kind of cognitive rehab Bob has gone though-both in a formal way, with a therapist, and informally, on his own?

The first thing I’d like to say is that rehab is a long process. Doctors told me that Bob, despite the severity of his injuries, had better chances to recover than other victims, because of the reserve of neurons and connections he had built thanks to Read the rest of this entry »

In an emerging, dynamic, high growth market, like brain training, it is difficult to make precise projections. But, we can observe a number of trends that executives, consumers, public policy makers, and the media should watch closely in the coming years, as brain fitness and training becomes mainstream, new tools appear, and an ecosystem grows around it.

1. We predict an increased emphasis on brain maintenance in locations ranging from retirement communities to gyms. As a computer-savvy baby boomer population looks for ways to stay mentally fit, brain fitness, or brain training, is becoming part of their vocabulary and concern.

2. Physical and mental exercise will be better integrated. Physical exercise has been shown to increase the rate of neurogenesis, whereas mental exercise helps ensure the survival of any newly created neurons. Today both activities usually take place in very different settings: the former, in health clubs, the later, in universities. We predict that the borders between them will become more diffuse. Expect new programs such as brain fitness podcasts that allow us to train working memory as we jog or exercise bikes with built-in brain games.

3. Watch for a Read the rest of this entry »