Here you have the October edition of our monthly newsletter covering cognitive health and brain fitness topics. Please remember that you can subscribe to receive this Newsletter by email, using the box at the top of this page.

We recently run an online survey among subscribers of our monthly eNewsletter, and over 500 people said we have helped them make better personal or professional decisions on how to maintain and improve brain fitness. Most gave very illuminating examples, which we are reading and enjoying as we speak.

Respondents also had many good questions to ask, so I have selected 15 common ones, paraphrased/ synthesized them below, and answered them by linking to our most relevant posts and resources. I hope you enjoy the FAQ session.

Q: I teach a brain fitness class at my library/ senior center/ school, using much of your info. Can you share some of your presentations?
A: Yes, we have just decided to share, using a Creative Commons Attribution No Derivatives License, the full presentation of my recent book talk at New York Public Library. As long as you give credit to SharpBrains and don’t modify it, you are free to use the presentation you can see and download HERE. The talk was videotaped, and will be available online soon, so please keep tuned.

Q: What exactly does neuroplasticity mean, and why is it so important for education and health?
A: Start by reading how learning changes your brain.

Q. Is this only relevant for older adults? Can I also apply it in the workplace (I am 47)
A. I strongly suspect you do have a human brain, so you may benefit from these Ten Habits of Highly Effective Brains. Further, HR departments would do well to start paying more attention to Cognitive Fitness and the Mature Workforce trends.

Q. I read so many conflicting things I don’t know where to start.
A. You are not alone. We should all be aware that It is Not Only Cars That Deserve Good Maintenance: Brain Care 101.

Q. How can my organization deliver brain fitness activities as a community service?
A. These articles will provide good guidelines and ideas: Retooling Use It or Lose It , and Public Libraries: Community-Based Health Clubs for the Brain.

Q. Everyone seems obsessed with brain games. What about meditation?
A. Check out Yes, You Can Build Willpower, and Mindfulness Meditation in Schools.

Q. Are software-based cognitive interventions effective?
A. As a category, it certainly seems so, as long as we ask the right questions, For Whom, For What?. For example, did you see this Science paper on how Cognitive Training Can Influence Dopamine System?.

Q. What about the trade-off between time invested vs benefits realized.
A. Efficiency and replicability of cognitive and brain-based outcomes seem to be, in fact, the strongest points of structured cognitive interventions. They seem to maximize the Cognitive Value of your Mental Workout.

Q. It sometimes looks like the whole field came out of nowhere, due to Nintendo Brain Age’s success, so we can’t be talking about something serious.
A: Nintendo did indeed create consumer awareness (for a product with little evidence) but “brain training” has solid roots in neuropsychology and cognitive neuroscience, as you can read in our interview with Elkhonon Goldberg.

Q. What about neurofeedback?
A. After years of much clinical use and little solid evidence, several important trials have been published in 2009, showing how neurofeedback can help diagnose and treat ADHD patients.

Q. How can one improve memory?
A. Well, the answer deserves a whole book, but we can offer some Tips to Improve Memory including Sleep, Practice and Testing.

Q. How can I choose one among the number of products making memory and brain claims?
A. We suggest you use this Evaluation checklist, and consider reading our consumer guide/ book.

Q. Any general tips for educators and lifelong learners?
A. Indeed, here you have these 10 Brain Tips to Teach and Learn.

Q. How can I keep track of all the new trends, companies and products? Our health system/ insurer/ senior community/ venture firm/ company needs to make good decisions.
A. Well, that’s why we publish market research, such as the one summarized in this Infographic: State of the Market 2009 and also recently launched a professional Network for Brain Fitness Innovation. You can also Save the Date for the upcoming SharpBrains Summit.

Q: Thank you for all the information you provide…but what I want more of is… brain teasers!
A. Understood. We will make sure to offer more, but you can try, right now, these Top 50 Brain Teasers and continue with more recent puzzles and brain games.

We’ll have an exciting session in Palo Alto on October 6th, as part of the BoomerTech series organized by the MIT Club and SmartSilvers. Let me share the details now.

Fact or Fad: Who is Shaping the Brain Fitness Market?
Description: Lots of buzz … Perhaps you think that “Senior Moments” are an inevitable part of aging. But research shows you may be able to keep your brain young and fit the same way you do your body, with exercise and training. With the success of Nintendo’s Brain Age, Posit Science and dozens of new software programs and games that promise “brain fitness”, the real question is: “Are we experiencing a fad, or an emerging new consumer market?”

Join our speaker, Alvaro Fernandez, author of the new book, The Sharp Brains Guide to Brain Fitness, and our expert panel to discuss:

* What are the top products on the market today?
* Can the emerging field of Brain fitness improve your job performance?
* How will consumers make informed decisions on what to buy and use?
* What are the emerging trends to leverage for entrepreneurs to jump into the marketplace?

Click Here to Register

Speaker, Panelist & Moderator

Alvaro Fernandez, SharpBrains — Alvaro is co-founder and CEO of SharpBrains, a leading market research firm that tracks the market and research for cognitive assessments, training, and games. A member of the World Economic Forum’s Global Agenda Councils, he has been quoted in The New York Times, The Wall Street Journal, USA Today, and more, and recently co-authored the book, The SharpBrains Guide to Brain Fitness: 18 Interviews with Scientists, Practical Advice, and Product Reviews, to Keep Your Brain Sharp. Alvaro received masters’ degrees in education and business from Stanford University, and teaches at UC-Berkeley Osher Lifelong Learning Institute.

Panelists

Roger Quy, General Partner, Technology Partners — Roger has been responsible for the life science practice of Technology Partners since 1989. He specializes in neurotechnology, investing in both biopharma and medical device companies. Roger began his career at the Queen Square Institute of Neurology, London where he was a Research Fellow for the British Medical Research Council. He developed and commercialized techniques for monitoring the brains of ambulatory patients. He contributed to a textbook on epilepsy and holds eight patents. Roger earned a BA with honors in psychology and law and a PhD in neuroscience from the University of Keele, England. He received an MBA from the Haas School of Business at the University of California, Berkeley.

Jan Zivic, Founder, Vibrant Brains — Jan’s interest in Brain Fitness is very personal. She suffered a traumatic brain injury after an automobile accident several years ago, and experienced the concept of neuroplasticity first-hand as she rehabilitated from not being able to walk or think rationally to restoring much of her previous function.

Jan has served in a variety of leadership roles including: the Board of Directors of the Yerba Buena Center for the Arts where she currently serves as President of the Board, the Library Commission of SF, the California Executive Recruiters Association (its first female President), the Katherine Delmar Burke Independent School, and The Family Services Agency of SF – President of the Board. Jan was recognized as The SF Cable Car Awards “Woman of the Year,” and later as the recipient of the Maya Angelou Community Leadership Award, from the University of California, San Francisco Medical School’s Center Of Excellence.

Date: Tuesday, October 6, 2009

Time:

* 6:00PM Registration, Hors d’oeuvres and Networking
* 7:00PM Presentation and Panel Discussion

Cost:

* $20.00 in advance on the website
* $25.00 Walk-ins at the door (cash or check please, no credit cards accepted at door)

Contact:

Michael Sarfatti
tel 415-885-2293
sarfatti@alum.mit.edu

Location:

Wilson Sonsini
950 Page Mill Road
Palo Alto, CA 94301

Click Here to Register

Have you already read The SharpBrains Guide to Brain Fitness?

Let’s see…

1. Pick the only part of your body that does not contain fat:

a. Arm
b. Thigh
c. Brain
d. None

Answer: d) Fats are also present in the brain: in neurons’ membranes to keep them flexible. These fats are the omega 3 and omega 6 fatty acids molecules. (Page 32 of the book)

2. Pick the only food product that doesn’t contain Omega-3 fatty acids

a. Tuna
b. Walnut
c. Kiwi
d. Jelly Beans

Answer: d) Fatty acids can be found in cold-water fish (such as mackerel, herring, salmon, and tuna), kiwi, and walnuts. (Page 33)

3. Pick the only food product that doesn’t contain antioxidants

a. Olive oil
b. Milk
c. Nuts
d. Berries

Answer: b) Antioxidants can be found in vegetable oils, nuts, green leafy vegetables (e.g., spinach), citrus fruit, and berries. (Page 33)

4. Chronic Stress cannot:

a. Prevent you from being creative
b. Kill brain cells
c. Prevent you from sleeping
d. Kill liver cells

Answer: d) Prolonged exposure to adrenal steroid hormones like cortisol, which is released into the blood stream when we are stressed, can lead to cell death and block the formation of new neurons. (Page 35)

5. What type of physical exercise is the best for your brain health?

a. Weight lifting
b. Aerobic exercises
c. Flexibility exercises Read the rest of this entry »

Here you have the August edition of our monthly newsletter covering cognitive health and brain fitness topics. Please remember that you can subscribe to receive this Newsletter by email, using the box at the top of this page.

Scientific publication Frontiers in Neuroscience recently published a special issue on Augmenting Cognition, and invited me to contribute with an article titled Preparing Society for the Cognitive Age. Groundbreaking brain research has occurred over the last 20 years. The opportunity to improve brain health and performance is immense, but we need to ensure the marketplace matures in a rational and sustainable manner, both through healthcare and non-healthcare channels. Click Here to read my article.

Announcements

In May 2009 SharpBrains published The State of the Brain Fitness Software Market 2009, the main industry report for leading organizations preparing their members, their clients, and their patients for the cognitive age. 150-pages long, the report includes a market survey with 2,000+ respondents, detailed analysis of 20+ vendors, research briefs written by 12 leading scientists and data and trends for 4 major customer segments.

Below we share the full Executive Summary of the report and announce an exclusive webinar on September 29th to discuss the State of the Market in more depth with buyers of the report.

To order the report and access both the report and the webinar, you can click Here. (Only $975 -a 25% discount- using Discount Code Frontiers2009 before September 28th).

State of the Market
 

Think about this: How can anyone take care of his or her brain when every week brings a new barrage of articles and studies which seem to contradict each other?

Do supplements improve memory? Do you need both physical and mental exercise –or is one of them enough? Which brain training approach, if any, is worth one’s time and money?

We tried to address these questions, and many others, in our recent book, The SharpBrains Guide to Brain Fitness (182 pages, $24.95), that we presented at Games for Health Conference last week. The book is the result of over two years of extensive research including more than a hundred interviews with scientists, professionals and consumers, and a deep review of the scientific literature, led by neuropsychologist Elkhonon Goldberg and myself with the help of cognitive scientist Pascale Michelon. As we wrote in the Introduction, what we wanted to do first of all was to debunks these 10 myths on brain health and brain training:

Myth 1. Genes determine the fate of our brains.
Facts: Lifelong neuroplasticity allows our lifestyles and actions to play a meaningful role in how our brains physically evolve, especially given longer life expectancy.

Myth 2. Aging means automatic decline.
Facts: There is nothing inherently fixed in the precise trajectory of how brain functions evolve as we age.

Myth 3. Medication is the main hope for cognitive enhancement.
Facts: Non-invasive interventions can have comparable and more durable effects, side effect-free.

Myth 4. We will soon have a Magic Pill or General Solution to solve all our cognitive challenges.
Facts: A multi-pronged approach is recommended, centered around nutrition, stress management, and both physical and mental exercise.

Myth 5. There is only one “it” in “Use It or Lose it”.
Facts: The brain is composed of a number of specialized units. Our life and productivity depend on a variety of brain functions, not just one.

Myth 6. All brain activities or exercises are equal.
Facts: Varied and targeted exercises are the necessary ingredients in brain training so that a wide range of brain functions can be stimulated.

Myth 7. There is only one way to train your brain.
Facts: Brain functions can be impacted in a number of ways: through meditation, cognitive therapy, cognitive training.

Myth 8. We all have something called “Brain Age”.
Facts: Brain age is a fiction. No two individuals have the same brain or expression of brain functions.

Myth 9. That “brain age” can be reversed by 10, 20, 30 years.
Facts: Brain training can improve specific brain functions, but, with research available today, cannot be said to roll back one’s “brain age” by a number of years.

Myth 10. All human brains need the same brain training.
Facts: As in physical fitness, users must ask themselves: What functions do I need to improve on? In what timeframe? What is my budget?

Do you have other myths in mind you would like  us to address?

We have started to receive great feedback from the healthcare community, such as this email from a neurosurgeon in Texas:

“I really like the book, it is comprehensive without being too technical. I have recommended it to several patients. There are some other books that I expected would be greeted with enthusiasm, but were too complex for most of my patients. I think this book is right in the sweet spot”.

And this great book review by an Internist Physician and Robert Wood Johnson Foundation Fellow, titled Is Your Brain A Couch Potato?:

“…a short, sweet, entertaining read of a complex topic, with timely (written in 1/09) reviews of 21 top technology products, as well as informed and expert predictions of where this burgeoning brain-fitness field is headed. More importantly, after you read it, you’ll have a good, detailed sense of where you, personally, can act to improve your own couch-potato brain – and how to keep it fit and flexible your whole life. The SharpBrains Guide To Brain Fitness reminds of us all why books (and not just googling a topic) can be well worth your time and money. Two Stethoscopes Up – check it out. life.”

—Doc Gurley, book review for SFGate.com (06/08/09)

The book:  The SharpBrains Guide to Brain Fitness (available via Amazon.com Here, review copies available upon request).

Description: While most of us have heard the phrase “use it or lose it,” very few understand what “it” means, or how to properly “use it” in order to maintain brain function and fitness. The SharpBrains Guide to Brain Fitness is an invaluable guide that helps readers navigate growing brain research and identify the lifestyle factors and products that contribute to brain health and fitness. By gathering insights from eighteen of the world’s top scientists and offering tools and detailed descriptions of over twenty products, this book is an essential guide to the field of brain fitness, neuroplasticity and cognitive health. An accessible and thought-provoking read, The SharpBrains Guide to Brain Fitness educates lifelong learners and professionals in healthcare, education, business, etc., on emerging trends and forecasts of what the future will hold.

Products Reviewed (we reviewed scientific studies published before January 2009, when the manuscript text was closed):

- Overall brain maintenance: Brain Age series (Nintendo), BrainWare Safari (Learning Enhancement Corporation), FitBrains.com (Vivity Labs), Happy-Neuron.com (Scientific Brain Training), Lumosity.com (Lumos Labs), MindFit (CogniFit), (m)Power (Dakim)

- Targeted brain workout: Classic and InSight (Posit Science), Working Memory Training JM and RM (Cogmed), DriveFit (CogniFit), Earobics (Houghton Mifflin), Fast ForWord (Scientific Learning), IntelliGym (Applied Cognitive Engineering), Vision Restpration Therapy (NovaVision)

- Emotional self-regulation: emWave PC and Personal Stress Reliever (HeartMath), Journey to the Wild Divine (Wild Divine), RESPeRATE (InterCure), StressEraser (Helicor)

Given the whole distracting “controversy” of whether Nintendo Brain Age “works” or not, I have started to use the following “brain teasers” in my talks in order to help the audience gain a more useful perspective of what is going on. They worked great both in the Medicare Readmissions Summit in DC a few weeks ago, and at the Games for Heath Conference last week.

Q: How many soldiers in the US Army have gone through computerized cognitive testing before being deployed, and why?
A: Over 150,000, in order to establish an objective starting baseline and identify potential Post Traumatic Stress Disorder (PTSD) and Traumatic Brain Injury (TBI) problems upon their return.

Q: How big is the ongoing investment by OptumHealth, a division of UnitedHealth Group (UNH), in developing computerized cognitive assessments to inform clinical decision-making?
A: over $6m.

Q: How many Allstate policy-holders over the age of 50 have received a computerized cognitive training program to improve their driving safety?
A: Over 8,000, in the state of Pennsylvania.

Q: How many residential communities are offering computerized cognitive training programs to their residents?
A: Over 700, in the US alone, covering independent and assisted living.

Q: How much money has the Government of Ontario invested in setting up a new Centre for Brain Fitness as part of Baycrest research center in order to develop and commercialize technologies to assess and enhance cognitive functions?
A: $10m, matched with another 10m from local investors.

For more on our Cognitive Health Track at Games for Health Conference last week, see this USA Today article:

More doctor’s prescriptions may include brain games to improve mental acuity

(pretty good overall, but please note that SharpBrains didn’t organize the whole conference, “only” the cognitive health track, which was a lot of stimulating fun. Ben Sawyer and team did overall conference).

After many many months of mental stimulation, physical exercise and the certain need for stress management… we have just announced the release of the The State of the Brain Fitness Software Market 2009 report, our second annual comprehensive market analysis of the US market for computerized cognitive assessment and training tools. In this report we estimate the size of the US brain fitness software market at $265M in 2008, up from $225M in 2007 (18% annual growth), and from $100m in 2005. Two segments fuelled the market growth from 2007 to 2008: consumers (grew from $80m to $95m) and healthcare & insurance providers (grew from $65m to $80m).

The 150-page report finds promising research and initiatives to drive significant growth, combined with increased consumer confusion given aggressive marketing claims and lack of education and standards. The report includes:
- The complete results of an exclusive January 2009 Survey with 2,000+ respondents
- A proprietary Market & Research Momentum Matrix to categorize 21 key vendors into four categories
- 10 Research Executive Briefs written by leading scientists at prominent research labs
- An analysis of the level of clinical validation per product and cognitive domain

Top 10 Highlights from the report:

1) Consumers, seniors’ communities and insurance providers drove year on year sustained growth, from $225m in 2007 to $265m in 2008. Revenues may reach between $1 billion to $5 billion by 2015, depending on how important problems (Public Awareness, Navigating Claims, Research, Health Culture, Lack of Assessment) are addressed.

2) Increased interest and confusion: 61% of respondents Strongly Agree with the statement “Addressing cognitive and brain health should be a healthcare priority.” But, 65% Agree/Strongly Agree “I don’t really know what to expect from products making brain claims.”

3) Investment in R&D seeds future growth: Landmark investments by insurance providers and government-funded research institutes testing new brain fitness applications planted new seeds for future growth.

4) Becoming standard in residential facilities: Over 700 residential facilities – mostly Independent and Assisted Living facilities and CCRCs – have installed computerized cognitive training programs.

5) Customer satisfaction: Consumers seem more satisfied with computer-based products than paper-based options. But, satisfaction differs by product. When asked “I got real value for my money”, results were as follows: Lumosity.com (65% Agree), Puzzle Books (60%), Posit Science (52%), Nintendo (51%) agreed. Posit Science (53% Agree) and Lumosity.com (51%) do better than Puzzle Books (39%) and Nintendo (38%) at “I have seen the results I wanted.”

6) Assessments: Increasing adoption of computer-based cognitive assessments to baseline and track cognitive functions over time in military, sports, and clinical contexts. The Alzheimer’s Foundation of America now advocates for widespread cognitive screenings after 65-75.

7) Specific computerized cognitive training and videogames have been shown to improve brain functions, but the key questions are, “Which ones”, and “Who needs what when?”

Aggressive marketing claims are creating confusion and skepticism, resulting in a distracting controversy between two misleading extremes: (a) “buying product XYZ can rejuvenate your brain Y years” or (b) “those products don’t work; just do one more crossword puzzle.” The upcoming book The SharpBrains Guide to Brain Fitness aims to help consumers navigate these claims.

9) Developers can be classified into four groups, based on a proprietary Market and Research Momentum Matrix: SharpBrains finds 4 Leaders, 8 High Potentials, 3 Crosswords 2.0, and 6 Wait & See companies.

10) Increased differentiation: Leading companies are better defining their value proposition and distribution channels to reach specific segments such as retirement communities, schools, or healthcare providers.

Leading researchers prepared 10 Research Executive Briefs:
- Dr. Joshua Steinerman (Einstein-Montefiore): Neuroprotection via cognitive activities
- Dr. Jerri Edwards (South Florida): Assessments of driving fitness
- Dr. Susanne Jaeggi and Dr. Martin Buschkuehl (Bern, Michigan): Working memory training and fluid intelligence
- Dr. Torkel Klingberg (Karolinska): Working memory training, dopamine, and math
- Dr. Liz Zelinski (UC Davis): Auditory processing training
- Dr. David Vance (UAB): Speed-of-processing training
- Dr. Jerri Edwards (South Florida): Cognitive training for healthy aging
- Dr. Daphne Bavelier & Dr. Shawn Green (Rochester): Action videogames and attentional skills
- Dr. Arthur Kramer (Illinois): Strategy videogames and executive functions
- Dr. Yaakov Stern (Columbia): The cognitive reserve and neuroimaging
- Dr. David Rabiner (Duke): Objective assessments for ADHD

Table of Contents

Editorial
Executive Summary
Chapter 1. Bird’s-Eye View of the Growing Field
Chapter 2. Market Survey on Beliefs, Attitudes, Purchase Habits
Chapter 3. The Emerging Competitive Landscape
Chapter 4. The Science for Brain Fitness and Cognitive Health
Chapter 5. Consumers – Adopting Crosswords 2.0?
Chapter 6: Healthcare and Insurance Providers – A Culture of Cognitive Health
Chapter 7: K12 School Systems- Ready for Change?
Chapter 8: Military, Sports Teams, Companies – Brain-Performance Link
Chapter 9: Future Directions – Projections and Bottlenecks

Companies profiled include: Advanced Brain Technologies, Applied Cognitive Engineering, Brain Center America, Brain Resource, CNS Vital Signs, Cogmed, Cogstate, CogniFit, Cognitive Drug Research, Dakim, Houghton Mifflin, Learning Enhancement Corporation, LearningRx, Lumos Labs, Marbles: The Brain Store, Nintendo, NovaVision, Posit Science, Scientific Brain Training, Scientific Learning, TransAnalytics, vibrantBrains, Vigorous Mind, Vivity Labs.

More on the report by clicking on The State of the Brain Fitness Software Market 2009.

Nintendo brain-trainer ‘no better than pencil and paper’ (The Times):
“The survey of ten-year-old children found no evidence to support claims in Nintendo’s advertising campaign, featuring Nicole Kidman, that users can test and rejuvenate their grey cells. “The Nintendo DS is a technological jewel. As a game it’s fine,” said Alain Lieury, professor of cognitive psychology at the University of Rennes, Brittany, who conducted the survey. “But it is charlatanism to claim that it is a scientific test.”

Comments: as we have said before, Nintendo Brain Age and Brain Training should be seen as what they are: a game. And the construct of one’s having a  “brain age” makes no sense.

Having said that, the researcher quoted then offers, out of the blue, a highly inaccurate statement:

“The study tested Nintendo’s claims on 67 ten-year-olds. “That’s the age where you have the best chance of improvement,” Professor Lieury said. “If it doesn’t work on children, it won’t work on adults.”

That assertion (that something won’t “work” on adults because it won’t “work” on kids) makes even less sense than having a “brain age”. The Cognitive Reserve research shows the need for lifelong mental stimulation – and the reality is that kids are more exposed to novelty and challenge all the time, whereas older adults may not be. Further, that claim (something that doesn’t “work” on kids won’t “work” on adults) has already been tested and proven wrong:

In a couple of recent trials, discussed here, the same strategy game (Rise of Nations, a complex challenge for executive functions), played for the same number of hours (23)  showed quite impressive (untrained) cognitive benefits in people over 60 – and no benefits in people in their 20s.

How can this be? Well, we often say that our brains need novelty, variety and challenge – and it should be obvious that those ingredients depend on who we are Read the rest of this entry »

Here you have several recent articles and developments worthy of attention:

1) Boom times for brain training games (CNN)
2) Navigating the brain fitness landscape: do’s and don’ts (McKnight’s Long Term Care News)
3) USA Hockey and Intelligym (press release)
4) Brain Fitness at New York Public Library (NYPL blog)
5) McDonnell Foundation grant harnesses cognitive science to improve student learning (press release)
6) Health insurance firms offering online cognitive therapy for insomnia (Los Angeles Times)
7) HeadMinder Cognitive Stability Index: Computerized Neurocognitive … (Press release)
THE AGE OF MASS INTELLIGENCE (Intelligent Life)
9) Working Later in Life May Facilitate Neural Health (Cerebrum)
10) The Cool Factor: Never Let Them See You Sweat (New York Times)

Links, selected quotes and commentary: Read the rest of this entry »

Crisp CNN article:

Boom times for brain training games

Including my final quote “[Brain fitness] is not just some fad. The market is much deeper than Nintendo.”

The “brain fitness center” financed by Ontario is Baycrest. Companies mentioned: Mindfit, Posit Science, Nintendo, Allstate, BrainBuilder, MyBrainTrainer.

The reporter and I also discussed in depth the need for better consumer education and professional development, so people can make informed decisions, and for cognitive assessments to serve as independent baseline, help identify priorities and measure results. Please note that our market estimates do include revenues of computerized cognitive assessments, today mostly used in clinical trials, and wthin the military and sports teams.