We are excited to invite you to the first virtual, global SharpBrains Summit (January 18-20th, 2010). The SharpBrains Summit will feature a “dream team” of over 25 speakers who are leaders in industry and research from 7 countries, to discuss emerging research, tools and best practices for cognitive health and performance. This inaugural event will expose health and insurance providers, developers, innovators at Fortune 500 companies, investors and researchers, to the opportunities, partnerships, trends, and standards of the rapidly evolving cognitive fitness field.

Register Today

Learn more and register Here today, at discounted early-bird rates, to receive these benefits:

• Learn: Full access to all Conference live sessions, and Downloadable Recordings and Handouts
• See: latest technologies and products during Expo Day
• Connect and Discuss: become a member of the SharpBrains Network for Brain Fitness Innovation (members-only LinkedIn Group) through the end of 2010, access online chats during the summit, meet other registrants in your city
• Understand the Big Picture: access 10 Research Executive Briefs prepared by leading scientists

On top of those early-bird discounts, we offer an additional 15% discount for SharpBrains readers who want Regular Admission. Discount code: sharp2010. You can register Here.

Agenda/ Speakers

Monday, January 18th, 2010:

(Preliminary schedule, US Pacific Time)

8-9.15am. Cognition & Neuroplasticity: The New Healthcare Frontier

• Alvaro Fernandez, SharpBrains
• David Whitehouse, OptumHealth Behavioral Solutions
• William Reichman, Baycrest
• P Murali Doraiswamy, Duke University

9.30-11am. Tools for Safer Driving: The Opportunity with Teenagers and Adults

• Steven Aldrich, Posit Science
• Shlomo Breznitz, CogniFit
• Jerri Edwards, University of South Florida
• Peter Christianson, Young Drivers of Canada

Noon-1.30pm. Baby Boomers and Beyond: Maintaining Cognitive Vitality

• Kunal Sarkar, Lumos Labs
• Elizabeth Zelinski, USC Davis School of Gerontology Read the rest of this entry »

A spate of recent news coverage on brain fitness and “brain training” reflects a growing interest in natural, non-drug-based interventions to keep our brains sharp as we age. This interest is very timely, given the aging population, increasing Alzheimer’s rates, and soaring health care costs that place more emphasis than ever on prevention and changing lifestyle.

This past Tuesday, the MIT Club of Northern California, the American Society on Aging, and SmartSilvers sponsored an event on The Emerging Brain Fitness Software Market: Building Better Brains to explore the realities and myths of this growing field. The panel was moderated by Zack Lynch, Executive Director of the Neurotechnology Industry Organization, and composed of a venture capitalist and 3 CEOs of program developers in the field. Before the panel, I had the chance to present an overview of the state of the Brain Fitness Software Market based on our upcoming report to be released on March 4th.

Why are we talking about this field at all? Well, for one, an increasing number of companies are achieving significant commercial success in packaging “brain exercise”. An example is the line of Nintendo games, such as Brain Age and Brain Training, that have shipped over 15 million units worldwide despite limited scientific support, since 2005. What is less visible is that a number of companies and scientists are Read the rest of this entry »

This is an event you may be interested in, if you are based in the San Francisco Bay Area.

The MIT Club of Northern California, American Society on Aging, The Business Forum on Aging and SmartSilvers presents:

The Emerging Brain Fitness Market:  Building Better Brains (Contact information and Registration Here)

Date: 02/12/2008 Tuesday
Time: 6:00pm
Venue: Wilson Sonsini
Location: 950 Page Mill Road, Palo Alto
Cost: $20 online, $25 walk-in

Contact information and Registration Here.

Here is the buzz … Scientific, technological and demographic trends have converged to create an exciting new market in brain fitness, where software and online applications can assess and train cognitive abilities. That equates to a sharper mind and better memory retention contributing to healthier aging.  There is currently a $400m worldwide market with high growth ahead predicted.

Join us in lively and informative discussions as Alvaro Fernandez; CEO of SharpBrains.com summarizes the science, key market segments, players and trends, based on the first Brain Fitness Software Market Report, presented in this event.  He will discuss the implications with several neuro-technology, gaming experts and investors.”   Moderated by Zack Lynch, the speaker and panel will discuss:  Read the rest of this entry »

The Neurotechnology Industry Organization (NIO) just announced the top ten emerging areas of neuroscience that will “impact the future of treatments for brain and nervous system”: Top 10 Neuroscience Trends in 2007.

It provides superb food for thought. And some of them will sound familiar to readers of this blog:

* 6. Normal brain aging gets more attention: More research and development is being focused on thinking impairments that only partially limit independence and quality of life for senior citizens, adults and school aged children. Neurosoftware will penetrate nursing homes and schools, as brain fitness software becomes new first-line treatment strategy.
* 8. Prevention evidence grows: You are what you eat; smoking is as bad as we thought; and new studies reveal the effects of environmental substances on Alzheimer’s disease, Parkinson’s disease and others.
* 9. Emotional disorders research advances:  New research continues to link neurogenesis to treatment of depression.  A better understanding of PTSD should lead to new treatment regimes.

Want to read probably the best overview of the neurosoftware/ brain fitness software market? Check this article, fresh from the oven: Thank Boomers for Buffing Up Brain Market.

To clarify the numbers mentioned: we project $225m in the US alone (growing from $70m in 2003), broken-down as follows: $80m for the Consumer segment, $60m in K12 Education, $50m in Clinical applications, and $35m in the Corporate segment. The Consumer segment, with a healthy aging value proposition, is the most recent one but the most rapidly growing.

Hi,

It’s Andreas, the neuroscience intern from Norway.

Lately, you might have noticed the comedian Judson Laipply’s awesome movie clip, the Evolution of Dance on Youtube?

The dance is part of Laipply’s “Inspirational Comedy” and has become a huge success. As a neuroscientist I’m interested in what are the neural substrates of dance? Further, I thought of ways to express this in an easy way so that people can learn more about the dance and the brain in a fun way. The result is my new Youtube video: A neurocomment on Laipply’s movie clip.

[youtube QQNhP2oOexU]
Read the rest of this entry »

Hi! It’s Andreas, the Norwegian MD/PhD intern at SharpBrains.

Last week Alvaro wrote about how people with low stress levels are better able to tolerate age-related changes in the brain. The other side of the coin, as mentioned today in the Wall Street Journal, is that chronic stress is a risk factor of dementia and might be related to harmful stress hormones called glucocorticoids.

So why do we have glucocorticoids? Well, they are steroids produced to help us manage short-term periods of stress. However, long-term release may erode pathways (connetions) between brain cells and can potentially accelerate cognitive decline.

Why is this relevant to all of us? Because depression can be seen as a chronic state of brain stress, and explain why stress management is important. Studies now show that depression may actually damage brain structures responsible for memory. The findings from a study in Archives of General Psychiatry showed patients with a history of depression are more likely to suffer from cognitive problems later in life, such as Alzheimer’s or dementia. As the journalist writes, “In findings that highlight the importance of mood and stress to maintaining a healthy brain, researchers and psychiatrists say that a bout of depression may raise the risks of developing dementia later in life.”

In some cases, patients with untreated depression exhibit an 10% volume reduction of the brain’s memory center Read the rest of this entry »

If you want to live long and strong, you’ve got to do more than work out your body; you’ve got to exercise your brain, insists Dr. Elkhonon Goldberg, clinical professor of neurology at New York University School of Medicine. While we’ve heard for years that mental stimulation can stave off dementia and Alzheimer’s, Dr. Goldberg says scientists now know exactly how to keep our brains from turning to mush – by stimulating the growth of new neurons and interconnections between them that boost brain efficiency. If you don’t use your brain in new and novel ways, your brain won’t be fit to use.

As the chief scientific adviser for SharpBrains.com, Dr. Goldberg’s site offers an array of brain teasers and exercises that improve brain function. But online tests are not all you can do. Just do something different and challenging. Getting out of your middle-aged comfort zone is the difference in a high quality of life when you’re older than none at all.

Keep reading more of the Florida Today interview with Dr. Goldberg at Next Up, A Gym for the Mind.

You can also read our more detailed (and probably more precise) interview with Dr. Elkhonon Goldberg on Brain Fitness and Cognitive Training.

A couple of good recent articles:

(You can join our monthly newsletter by subscribing at the top of this page).

Brain Games will give adults all the challenge they can handle

Baltimore Sun, MD. Mar 22, 2007.The reporter provides a great survey of products. The only parts I find missing are:

1) what specific cognitive skill/s is/are being trained by each product? if we understand that the brain has a variety of structural and functional areas, it becomes evident that different programs may be training different “mental muscles”.

2) How does each program enable the user measure progress in an objective way? I’d say this is the main difference between “games” and brain fitness programs. If you have a wildly different brain age everytime you try…that so-called brain age is not very credible.

Does brain exercise fight dementia?
Minneapolis Star Tribune (subscription), MN. Mar 18, 2007.As the article mentions, no program can claim to “prevent Alzheimer’s”. And I haven’t seen Posit Science (or us) claim such a thing, or imply it. But what can be claimed is meaningful: Read the rest of this entry »

Several recent stories on brain training and SharpBrains:

1) New brain games may improve mind fitness by Kevin Kosterman (U of Wisconsin Oshkosh’s Advance-Titan)

“Anytime we learn, we are training, changing, our brain,” Fernandez said. “The three key core elements for effective brain exercise are novelty, variety and constant challenge, similar to increasing the level in machines we find in gyms.”

2) “Training the Brain as possible as Training the Body”, جريدة النهار by Hanadi El Diri (Annahar, one of the most prestigious papers in the Middle East. The text is in Arabic.)

3) “Train your brain” by Mark Muckenfuss (The Press-Enterprise in Riverside and San Bernardino)

“We cannot promise to people you will only keep getting better until you are 200 years old. But I think people still underestimate how flexible the brain really is.”

The SmartBrains [sic] program combines mental exercises with a stress reduction program. Too much stress, says Fernandez, has been shown to be damaging not only to performance, but to the brain itself.
With all of the available programs for stimulating the brain, he says, it is important to shop carefully. A critical element, he says, is how clients or participants are evaluated.

“Make sure they have a credible assessment that helps you find your strengths and weaknesses and that they have programs that address (those areas),” he says. “Assessments that give you 50 (as an age-equivalent grade) and a week later you’re 32, that’s not a valuable assessment.”

Update: we now have an in-depth interview with Yaakov Stern, leading advocate of the cognitive reserve theory, and one of the authors of the paper we review below: click on Build Your Cognitive Reserve-Yaakov Stern. 

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In honor of the Week of Science presented at Just Science from Monday, February 5, through Sunday, February 11, we will be writing about “just science” this week. We thought we would take this time to discuss more deeply some of the key scientific publications in brain fitness.

Today, we will highlight the key points in an excellent review of cognitive reserve: Scarmeas, Nikolaos and Stern, Yaakov. Cognitive reserve and lifestyle. Journal of Clinical and Experimental Neuropsychology. 2003;25:625-33.

What is Cognitive Reserve?
The concept of a cognitive reserve has been around since 1998 when a post mortem analysis of 137 people with Alzheimer’s Disease showed that the patients exhibited fewer clinical symptoms than their actual pathology suggested. (Katzman et al. 1988) They also showed higher brain weights and greater number of neurons when compared to age-matched controls. The investigators hypothesized that the patients had a larger “reserve” of neurons and abilities that offset the losses caused by Alzheimer’s. Since then the concept of cognitive reserve has been defined as the ability of an individual to tolerate progressive brain pathology without demonstrating clinical cognitive symptoms.
Read the rest of this entry »