We are now finalizing agenda and contacting sponsors and partners. Details will be ready, and registration open, by the end of October. In the meantime, please Save the Date if you are interested in participating: January 18-20th 2010 (Pacific Time).

• Conference: January 18-19th. A series of 30-minute sessions (20-minute presentation, 10-minute Q&A), to discuss Market and Research Insights,  together with online discussions and, in some cities, social gatherings of participants.
• Expo Day: January 20th. Product demos by Sponsors.

Confirmed speakers and themes:

Monday, January 18th, 2010:

Cognition and Neuroplasticity: The New Healthcare Frontier

• Alvaro Fernandez, CEO, SharpBrains
• David Whitehouse, Chief Medical Officer, OptumHealth Behavioral Solutions
• William Reichman, President, Baycrest
• P Murali Doraiswamy, Biological Psychiatry Division Head, Duke University

Tools for Safer Driving: Teenagers and Older Adults

• Steven Aldrich, CEO, Posit Science
• Peter Christianson, President of Young Drivers of Canada
• Jerri Edwards, Assoc. Professor University of South Florida

Clinical Applications: Researching, Identifying, Treating Cognitive Deficits

• Keith Wesnes, Practice Leader, United BioSource Corporation
• Jonas Jendi, CEO, Cogmed
• Michel Noir, President, Scientific Brain Training
• Elkhonon Goldberg, Chief Scientific Advisor, SharpBrains

Read the rest of this entry »

(Editor’s Note: given the growing media attention to three apparently separate worlds -cognitive enhancement via drugs, brain fitness training software, computerized neurocognitive assessments-, I found it refreshing to see our co-founder Elkhonon Goldberg introduce the topic of cognotropic drugs with an integrative perspective in the much updated new edition of his classic book, now titled The New Executive Brain: Frontal Lobes In A Complex World. Below goes an excerpt).

For many neuropsychologists, like myself, science is a labor of love, but seeing patients is bread and butter. Traditionally, the clinical contribution of neuropsychology has been mostly diagnostic, with precious little to offer patients by way of treatment. Neuropsychology is not the only clinical discipline for years consigned to helpless voyeurism. Every discipline concerned with cognition shares this humbling predicament. A psychiatrist treating a schizophrenic patient or a depressed patient finds him- or herself in a similar position. There are ample pharmacological tools to treat the patient’s psychosis or mood, but very few to treat the patient’s cognition. Even though psychiatrists increasingly recognize that cognitive impairment is often more debilitating in their patients than psychosis or mood disorder, traditionally, very little direct effort has been aimed at improving cognition.

A neurologist treating a patient recovering from the effects of head injury does not fare much better. There are adequate means to control the patient’s seizures but not his or her cognitive changes, despite the fact that cognitive impairment is usually far more debilitating than an occasional seizure. Society has been so preoccupied with saving lives, treating hallucinations, controlling seizures, and lifting depression that cognition (memory, attention, planning, problem solving) has been largely ignored. Granted, various neuroleptics, anticonvulsants, antidepressants, sedatives, and stimulants do have an effect on cognition, but it is an ancillary effect of a drug designed to treat something else.

Alzheimer’s disease and other dementias have been society’s wake-up call. Here, in the most affluent country in the most affluent of times, human minds were succumbing to decay before human bodies, a sharp challenge to the tacit popular belief that the “body is frail but soul is forever.” This provided an impetus for the development of an entirely new class of drugs, which can be termed familially as “cognotropic.” Their primary and explicit purpose is to improve cognition.

Since medical and public preoccupation with dementia focuses on memory, most of the pharmacological efforts have been directed at improving memory. At the time of this writing, a handful of drugs known as “Alzheimer’s drugs” or “memory enhancers” have been approved by the U.S. Food and Drug Administration (FDA). In reality, both designations are somewhat misleading. The drugs in question are Read the rest of this entry »

(Editor’s note: this article belongs to the excellent May 2009 special issue on Augmenting Cognition of scientific journal Frontiers in Neuroscience, Volume 3, Issue 1. You can order this issue, for 50 euros, here. Highly recommended for scientists and technical readers interested in the science. This article, an industry overview, is reproduced here with authorization by the Frontiers Research Foundation).

Preparing Society for the Cognitive Age

- By Alvaro Fernandez

Groundbreaking cognitive neuroscience research has occurred over the last 20 years – without parallel growth of consumer awareness and appropriate professional dissemination. “Cognition” remains an elusive concept with unclear implications outside the research community.

Earlier this year, I presented a talk to health care professionals at the New York Academy of Medicine, titled “Brain Fitness Software: Helping Consumers Separate Hope from Hype”. I explained what computerized cognitive assessment and training tools can do (assess/enhance specific cognitive functions), what they cannot do (reduce one’s “brain age”) and the current uncertainties about what they can do (i.e., delay Alzheimer’s symptoms). At the same symposium, Dr. Gary Kennedy, Director of Geriatric Psychiatry at Montefiore Medical Center, provided guidance on why and how to screen for executive function deficits in the context of dementia.

I could perceive two emerging trends at the event: 1) “Augmenting Cognition” research is most commonly framed as a healthcare, often pharmacological topic, with the traditional cognitive bias in medicine of focusing on detection and treatment of disease, 2) In addition, there is a growing interest in non-invasive enhancement options and overall lifestyle issues. Research findings in Augmenting Cognition are only just beginning to reach the mainstream marketplace, mostly through healthcare channels. The opportunity is immense, but we will need to ensure the marketplace matures in a rational and sustainable manner, both through healthcare and non-healthcare channels.

In January 2009, we polled the 21,000 subscribers of SharpBrains’ market research eNewsletter to identify attitudes and behaviors towards the “brain fitness” field (a term we chose in 2006 based on a number of consumer surveys and focus groups to connect with a wider audience). Over 2,000 decision-makers and early adopters responded to the survey.

One of the key questions we asked was, “What is the most important problem you see in the brain fitness field and how do you think it can be solved?”. Some examples of the survey free text answers are quoted here, together with my suggestions.

Most important problems in the brain fitness field

• Public awareness (39%): “To get people to understand that heredity alone does not decide brain functioning”. We need to ramp up efforts to build public awareness and enthusiasm about brain research, including establishing clear links to daily living. We can collaborate with initiatives such as the Dana Foundation’s Brain Awareness Week and use the recent “Neuroscience Core Concepts” materials developed by the Society for Neuroscience to give talks at schools, libraries and workplaces.

• Claims (21%): “The lack of standards and clear definitions is very confusing, and Read the rest of this entry »

The Longevity Dividend is a theory that says we hope to intervene scientifically to slow the aging process, which will also delay the onset of age-related diseases. Delaying aging just seven years would slash rates of conditions like cancer, diabetes, Alzheimer’s disease and heart disease in half. That’s the longevity part.

The dividend comes from the social, economic, and health bonuses that would then be available to spend on schools, energy, jobs, infrastructure—trillions of dollars that today we spend on healthcare services. In fact, at the rate we’re going, by the year 2020 one out of every $5 spent in this country will be spent on healthcare. Obviously, something has to change.

Enter the Longevity Dividend. The Longevity Dividend doesn’t suggest that we live longer; instead, it calls for living better. The idea is that if we use science to increase healthspan, not lifespan. In other words, tomorrow’s 50-year-old would have the health profile of a 43-year-old.

It might sound like science fiction, but, in fact, it’s quite possible. We’re already doing it in some animal models using genetic and dietary interventions, techniques related to what scientists call “the biology of aging.”

Getting there in humans, however, means embracing an entirely new approach to our thinking about disease and aging, and how we conduct scientific research into the two.

Getting Scientists’ Attention

A group of eminent researchers first proposed the Longevity Dividend in a 2006 article published in The Scientist. The authors, S. Jay Olshansky, PhD, professor of epidemiology and biostatics at the University of Illinois in Chicago, Daniel P. Perry, executive director of the Alliance for Aging Research in Washington, DC, Richard A. Miller, MD, PhD, professor of pathology at the University of Michigan in Ann Arbor, and Robert N. Butler, MD, president and CEO of the International Longevity Center in New York, intended their essay to be a “general statement to scientists” about the need for a paradigm shift in the way we think about aging and disease.

The researchers also met with U.S. senators who served on the Senate committee that oversaw the budget for the National Institutes of Health (NIH). “We told them we believed Read the rest of this entry »

Hiroshi Komiyama, President of the University of Tokyo and Chairperson of the Global Agenda Council on the Challenges of Gerontology I am a member of, just provided council members with a brief update of his participation in the recent World Economic Forum.

Part of the proceedings are public – you may enjoy reading this panel write-up of the session Healthcare under Stress:

- “Japan has the world’s oldest population. Health and longevity create wealth and, thus, “health begets wealth”. It is documented that nations that develop a five-year life expectancy advantage also create a larger GDP. A healthy childhood and adulthood contribute to a more productive old age. New markets and industries are arising – “silver industries” such as financial services, health, housing and hospitality geared to senior citizens. Longevity needs to be linked to health – including cognitive health – and lifestyle choices play a major role in health.”

- “The public health focus is shifting from infections to cardiovascular diseases. Complex new models are necessary to develop better responses and improved health – with the primary emphasis on “really good primary healthcare” and prevention – to lower costs. Prevention increases the healthy years of a person’s life. The challenge is creating the incentive for prevention: how can people be encouraged to make healthy choices? Mobilized populations can drive the change. Finland has an 80% lower incidence of heart disease than 30 years ago due to such incentives.”

Full write-up: Healthcare under Stress

Related articles:

- The Future of the Aging Society: Burden or Human Capital?

- Update: Global Consortium for Neurocognitive Fitness Innovation

Welcome to the 61st edition of Encephalon, the blog carnival that offers some of the best neuroscience and psychology blog posts every other week.

We do have an excellent set of articles today. covering much ground. Enjoy the reading:

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Neuroscience and Society

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Alzheimer’s Disease and Neurocognitive Health Read the rest of this entry »

Imagine seeing a top sheik from Dubai, wrapped in traditional Arab clothing, exclaim “Yes We Can” in front of the 800 experts gathered during the Summit of the Global Agenda that just took place in Dubai, co-organized by the World Economic Forum and the Government of Dubai. This same sheik added that “we build the future with our own hands”.

You can read more about the main points of the Global Agenda Councils conversation here: Discussion Highlights. Below go some of my own still-jetlagged reflections.

The financial crisis has made obvious the obvious: that we live in a truly new and global world.

And that business as usual will lead to global disaster – we need new approaches to collectively adapt to and thrive in this new environment. The answer is not to go back to any old paradigm, which simply will not work in a new reality, but to imagine and build a better new way of doing things.

Some of the attendants urged us to “reboot” the system. I don’t think that a “reboot” is enough – we need to upgrade to a new operating system. We can call it Planet Earth 2.0.Based on the group discussion we had on Sunday morning, let me propose some of the architectural principles that should underlie any emerging Planet Earth 2.0 operating system. Read the rest of this entry »

As mentioned before, the World Economic Forum asked me to write “an 800 words summary of your most compelling actionable idea on the challenges of gerontology”, in preparation for the Inaugural Summit of the Global Agenda that will take place November 7 to 9th in Dubai.A good number of SharpBrains readers and clients offered their insights – and expressed an interest in reading the draft. So below you have – a proposal to create a Global Consortium for Neurocognitive Fitness Innovation, building on our existing market research and advisory services work. Your thoughts?

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The Context

Growing Demands on Our Brains: Picture 6.7 billion Primitive Brains inhabiting a Knowledge Society where lifelong learning and mastering constant change in complex environments are critical for productive work, health and personal fulfillment.

Welcome to Planet Earth, 2008.

Further stretched by increased longevity: Now picture close to 1 billion of those brains over the age of 60 – and please remember that, less than 100 years ago, life expectancy was between 30 to 40 years. The rapidly evolving Knowledge Society is placing new and enormous demands on our “primitive” human brains. And the longer our lifespans, the more obvious the “cognitive gap”. Hence, from a health point of view, the growing Read the rest of this entry »

Just saw a very interesting press release regarding computer-based neurocognitive assessments – a critical part of the brain fitness puzzle. How long will it take before consumers can have access to a reliable and credible annual “mental check-up”/ cognitive baseline?

HeadMinder Cognitive Stability Index: Computerized Neurocognitive … (Press release)

- “The HeadMinder web-based Cognitive Stability Index (CSI) has proven more useful for blast-concussion detection than the ANAM computerized test battery the DoD currently employs. The CSI provides an immediate solution to clear the backlog of 400,000 IED-exposed service members in less than two years.”

- “The CSI is a 30-minute, Internet-based, computerized test that provides automated, objective measures of attention, memory, response speed, and processing speed for initial evaluation of cognitive functioning. The CSI produces standardized reports that enable triage and decision-making appropriate to a user’s qualifications – from medic to neuropsychologist to neurologist and other treatment team members.”

We covered this emerging type of assessments in the article Computerized Cognitive Assessments: opportunities and concerns

- “In fact, one of the Read the rest of this entry »

Some very interesting brain fitness software market news:

1) Scientific Learning To Buy Out Soliloquy

- “Scientific Learning Corp. has announced that it will acquire Soliloquy Learning from JTT Holdings. Both Scientific Learning and Soliloquy provide technology solutions for education. The acquisition will cost SLC about $11 million and is expected to be completed this month.”

- “Scientific Learning is the developer of Fast ForWord, a family of reading intervention tools targeted toward students who are characterized as struggling learners and designed to develop the required “neurocognitive skills” for reading and learning in general. Soliloquy is also a reading intervention developer.”

Comment: this acquisition consolidates Scientific Learning (NSDQ: SCIL) as the leading company in the education segment of the brain fitness market. It will be interesting to track what research gets done on the neural and cognitive effects of Soliloquy, since Scientific Learning’s Fast Forword is backed by extensive literature.

2) Technomedia Partners With SBT to Accelerate Its International Expansion

- “Technomedia, a Canadian provider of talent management and human capital development solutions, announced its partnership with the SBT (Scientific Brain Training) group, a European provider of training and evaluation of cognitive functions.” Read the rest of this entry »