(Editor’s Note: I recently came across an excellent book and resource, The Alzheimer’s Action Plan: The Experts’ Guide to the Best Diagnosis and Treatment for Memory Problems, just released in paperback. Dr. Murali Doraiswamy, one of the authors and leading Alzheimer’s expert, kindly helped us create a 2-part article series to share with SharpBrains readers advice on a very important question, “How can we help the public at large to distinguish Alzheimer’s Disease from normal aging — so that an interest in early identification doesn’t translate into unneeded worries?” What follows is an excerpt from the book, pages 3-8).

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As it turns out, Jane did not have Alzheimer’s. She consulted a doctor, who, in docspeak, told her that the passage of time (getting older) had taken a slight toll on her once-superquick memory. She was slowing down a little, and if she relaxed, the name or date or other bit of information she needed would come to her soon enough. She was still good at her job and home life. She had simply joined the ranks of the worried well.

Normal brain aging, beginning as early as the forties in some people, may include:

• Taking longer to learn or remember information
• Having difficulty paying attention or concentrating in the midst of distractions
• Forgetting such basics as an anniversary or the names of friends
• Needing more reminders or memory cues, such as prominent appointment calendars, reminder notes, a phone with a wellstocked speed dial

Although they may need some assistance, older people without a mental disorder retain their ability to do their errands, handle money, find their way to familiar areas, and behave appropriately.

How does this compare to a person with Alzheimer’s? When Alzheimer’s slows the brain’s machinery, people begin to lose their ability to Read the rest of this entry »

We offered some Brain Fitness Predictions in our Market Report , including…

“7. Doctors and pharmacists will help patients navigate through the overwhelming range of available products and interpret the results of cognitive assessments. This will require significant professional development efforts, given that most doctors today were trained under a very different understanding of the brain than the one we have today.”

The American Medical News, a weekly newspaper for physicians published by the American Medical Association, just published an excellent article along those lines:

Steps to a nimble mind: Physical and mental exercise help keep the brain fit
– Neuroscience is uncovering techniques to prevent cognitive decline.

A few quotes:

- It’s an example that highlights a wave of new thinking about the importance of brain fitness.

- Until recently, conventional wisdom held that our brains were intractable, hard-wired computers. What we were born with was all we got. Age wore down memory and the ability to understand, and few interventions could reverse this process. But increasingly, evidence suggests that physical and mental exercise can alter specific brain regions, making radical improvements in cognitive function.

- With nearly 72 million Americans turning 65 over the next two decades, physicians need the tools to handle growing patient concerns about how to best maintain brain health. Armed with this new brand of science, frontline physicians will be better equipped to address the needs of aging baby boomers, already in the throes of the brain fitness revolution.

- “Encourage them to exercise the brain in novel and complex ways,” he says.

Full article: here

One of the physicians quoted in the article is Gary J. Kennedy, MD, Director of the Division of Geriatric Psychiatry at Montefiore Medical Center in NYC and a professor in the Dept. of Psychiatry and Behavioral Sciences at Albert Einstein College of Medicine.

To put the AMA article in better perspective for SharpBrains readers, we asked Dr. Kennedy a few follow-up questions. Below you have his questions.

Alvaro Fernandez (AF): Can you summarize how cognitive functions tend to evolve as we age?

Gary Kennedy (GK): As we age cognitive functions that rely on Read the rest of this entry »

Our fellow blogger Jeremy over at PsyBlog has written a thoughtful post comparing the value of a number of cognitive enhancing tools. His overall verdict?

“The evidence for exercise boosting cognitive function is head-and-shoulders above that for brain training, drugs, nutritional supplements and meditation. Scientifically, on the current evidence, exercise is the best way to enhance your cognitive function. And as for its side-effects: yes there is the chance of an injury but exercise can also reduce weight, lower the chance of dementia, improve mood and lead to a longer life-span. Damn those side-effects!”

Article: Which Cognitive Enhancers Really Work: Brain Training, Drugs, Vitamins, Meditation or Exercise?

Jeremy, I started writing this as a comment to your post in your blog, but then it got too long. Let me write my reaction to your post here. 

While I appreciate your analysis and share most of your points, I think the “ranking” effort (this type of intervention is better than that one) is ultimately misleading.  It is based on a faulty search for a general solution/ magic pill for everyone and everything.

If only things were so simple. Perhaps one day there will be research to support that view, but certainly not today. A number of interventions have shown their value. In different populations, and contexts. For “exercise is the best way to enhance your cognitive function” to be true, one needs to have a pretty specific understanding of “best”, “your” and “cognitive function”.

Read the rest of this entry »

Today we have a number of industry announcements:

1) New editions of these Blog Carnivals (collections of blog posts around specific topics)

• Encephalon (neuroscience)
• Grand Rounds (medicine)
• Education (guess!)
• Happiness

2) The Neurotechnology Industry Organization has launched a Neurotech Job Board dedicated to commercial neuroscience (mostly focused on clinical applications, like drugs and devices, not so much on prevention, health & wellness). And the Kaiser Foundation Rehabilitation Center is looking for a Research Project Manager.

3) The American Association for the Advancement of Science has finally released a report of the human enhancement workshop that took place in June 2006. Read more about it at Zack’s blog.

4) Stephanie West Allen and Dr. Jeffrey Schwartz announce the Schedule of Events for their Brains On Purpose™ Seminars (”looking at conflict and the process of conflict resolution through the lens of neuroscience”): Colorado in October and Portland in November.

5) Registration is now open for my class on The Science of Brain Health and Brain Fitness (more here), October 9–30, at UC Berkeley Osher Lifelong Learning Institute (OLLI).

6) A couple of great Read the rest of this entry »