As you have probably seen, the Cognitive Health and Brain Fitness field is rapidly evolving, so let me highlight some of the main recent developments affecting the field:

1) Public policy initiatives:
- The Government of Ontario, Canada, announced a $10m investment in Baycrest Research Center to help develop and commercialize brain fitness technologies. This $10m investment was matched with an additional $10m by local investors.
- In the US, The Paul Wellstone and Pete Domenici Mental Health Parity and Addiction Equity Act of 2008 was signed into law, included in the recently-approved economic bailout bill. The passage of this law has significant implications for healthcare providers and technology vendors alike.

2) Computerized Cognitive Assessments Used by the US Military:
The US Army launched a new policy requiring cognitive screenings of all soldiers before deployment (in order to better diagnose potential problems such as PTSD and TBI upon return). ANAM was the selected computerized battery of tests.

3) Venture & Angel Fundraising for Cognitive Training companies:
A number of developers have raised money. CogniFit received $5m (from Milk Capital), Lumos Labs $3m (FirstMark Capital -previously called Pequot Ventures-, Norwest Venture Partners), Scientific Brain Training $1.5m (issued shares), Vivity Labs $1m (undisclosed angel investors), This is, of course, on top of the February $10.6 investment in Dakim (Galen Partners) that we already included in our market report.

4) Major Initiatives by Insurance Companies:
- Allstate launched a large-scale research project to measure impact of Posit Science InSight (visual processing training) on driver safety for adults over 50.
- OptumHealth announced a 3-year, $18m agreement with Brain Resource to offer web-based cognitive assessments as part of clinicians’ decision support systems.
- Humana decided not to renew its agreement with Posit Science to offer Posit’s auditory processing training program to Medicare members.

5) New Research:
- In a significant new study, a team from the University of Michigan published a high-quality paper in the Proceedings of the National Academy of Sciences showing how computerized working memory training can generalize and improve fluid intelligence (one of the domains that tends to decline with age).
- Learning and Teaching Scotland released an internal study showing how Nintendo Brain Training can help children’s math and concentration skills. The study gained significant media attention, despite the fact it hasn’t been published in a respected journal.

Note: This is an excerpt from the 6-Month Market Update we will  release later this month, covering the many important developments that have occurred since we launched the inaugural Brain Fitness Market Report in March this year. This special report will be available exclusively for our Premium Research Sponsors.

Quick links to excellent resources:

1) FEATURE-Brain fitness seen as hot industry of the future (Reuters)

2) Learning & the Brain Conference for Educators and Clinicians. April 26-29, 2008. Cambridge, MA

3) Brain Health Across the Lifespan Seminar for Health & Aging Professionals. May 15th, 2008. San Francisco, CA

For more info, Read the rest of this entry »

Bill Gates delivered a very inspiring commencement speech in Harvard last week. I recommend reading the full Remarks of Bill Gates and reflecting on his core message, which may be summarized in its last sentence:

• “And I hope you will come back here to Harvard 30 years from now and reflect on what you have done with your talent and your energy. I hope you will judge yourselves not on your professional accomplishments alone, but also on how well you have addressed the world’s deepest inequities … on how well you treated people a world away who have nothing in common with you but their humanity.”

A noteworthy aspect of the speech was the display of what neuropsychologists call Executive Functions, which are mostly located in our Frontal Lobes-the most recent part of our brains in evolutionary terms, and that enable us to learn and adapt to new environments. What makes a “sharp brain”. You can read more about this in our post Executive Functions and MacArthur “Genius Grants”.

See here Bill Gates’ advice on how to find solutions in complex environments-and how he applies a learned pattern to guide his actions in the field of AIDS prevention:

• “Cutting through complexity to find a solution runs through four predictable stages: determine a goal, find the highest-leverage approach, discover the ideal technology for that approach, and in the meantime, make the smartest application of the technology that you already have — whether it’s something sophisticated, like a drug, or something simpler, like a bednet.”
• “The AIDS epidemic offers an example. The broad goal, of course, is to end the disease. The highest-leverage approach is prevention. The ideal technology would be a vaccine that gives lifetime immunity with a single dose. So governments, drug companies, and foundations fund vaccine research. But their work is likely to take more than a decade, so in the meantime, we have to work with what we have in hand – and the best prevention approach we have now is getting people to avoid risky behavior.”
• “Pursuing that goal starts the four-step cycle again. This is the pattern. The crucial thing is to never stop thinking and working – and never do what we did with malaria and tuberculosis in the 20th century – which is to surrender to complexity and quit.”
• “The final step – after seeing the problem and finding an approach – is to measure the impact of your work and share your successes and failures so that others learn from your efforts.”

Certainly, good advice for us too to refine our Brain Fitness efforts. Here you have a relevant fragment of my (AF)recent interview with Dr. Elkhonon Goldberg (EG):

AF: Please tell us more about what the Frontal Lobes are

EG: We researchers typically call them the Executive Brain. The prefrontal cortex is young by evolutionary terms, and is the brain area critical to adapt to new situations, plan for the future, and self-regulate our actions in order to achieve long-term objectives. We could say that that part of the brain, right behind our forehead, acts as the conductor of an orchestra, directing and integrating the work of other parts of the brain.

I provide a good example in The Executive Brain book, where I explain how I was able to organize my escape from Russia into the US.

Significantly, the pathways that connect the frontal lobes with the rest of the brain are slow to mature, reaching full operational state between ages 18 and 30, or maybe even later. And, given that they are not as hard-wired as other parts of the brain, they are typically the first areas to decline.

Well, I’d say Mr. Gates has pretty mature and solid pathways!