Over the last months, thanks to the traffic growth of SharpBrains.com (over 100,000 unique visitors per month these days, THANK YOU for visiting today and please come back!), a number of proactive book agents, publishers and authors have contacted us to inform us of their latest brain-related books. We have taken a look at many books, wrote reviews of The Dana Guide to Brain Health book review and Best of the Brain from Scientific American, and interviewed scientists such as Judith Beck, Robert Emmons and James Zull.

Now we are launching a new Author Speaks Series to provide a platform for leading scientists and experts writing high-quality brain-related books to reach a wide audience. We are honored to start the series with an article by Larry McCleary, M.D, former acting Chief of Pediatric Neurosurgery at Denver Children’s Hospital, and author of The Brain Trust Program: A Scientifically Based Three-Part Plan to Improve Memory, Elevate Mood, Enhance Attention, Alleviate Migraine and Menopausal Symptoms, and Boost Mental Energy (Perigee Trade, 2007).

Without further ado, let’s enjoy Dr. McCleary’s article:

Brain Evolution and Why it is Meaningful Today to Improve Our Brain Health

You may feel overwhelmed by the stream of seemingly contradictory suggestions regarding the best way to maintain mental clarity as you age. Based on an analysis of seminal factors in the development of modern brain anatomy, I believe it is possible to make some very compelling recommendations for growing big brains, enhancing their function, and making them resistant to the aging process. These may be loosely categorized as factors pertaining to the mental or physical attributes of the brain. Although they are not truly independent entities, such a conceptualization provides a basis for the generation of brain healthy prescriptions. Diet, physical exercise, and stress reduction enhance neuronal resilience. Sleep and mental stimulation are vital for cognitive ability, learning, and memory.

Diet: Follow a modern shore-based/marine diet including seafood in its most general sense, non-starchy vegetables of all colors, berries, and eggs. Other sources of lean protein containing long-chain omega 3 fatty acids such as free range beef, chicken, bison, or elk are nutritious alternatives.

Physical exercise (Think ‘fight or flight’ activity.): Include all types. Aerobic activities such as swimming, bicycling, walking, or hiking for promotion of vascular health and weight control; resistance training for promotion of neurotrophic factors, naturally occurring compounds that make brain cells more resistant to aging, such as IGF-1 (Insulin-like growth factor-1) and BDNF (Brain-derived neurotrophic factor); and balance, coordination, and agility training such as ping-pong, balance beam, trampoline, and jumping rope to enhance cognitive speed and motor skills.

Stress Control: From an evolutionary perspective, stressors (such as meeting a cave bear) and intense physical activity (running or fighting) were brief in duration and usually occurred together. Modern stressors (psychological or emotional stress) tend to be unremitting and are generally uncoupled from the physical (fight or flight) component, meaning stress develops without any associated physical activity. Such intense physical pursuits are now called exercise. Not surprisingly, exercise is a perfect physiologic antidote for stress due to its beneficial impact on cortisol (the ‘stress’ hormone) and blood pressure and should be incorporated into any program of stress reduction.

Adequate sleep: The body needs rest, but the brain requires sleep. Acute or chronic sleep deprivation causes devastating short and long-term consequences to brain anatomy (synaptic loss) and function (memory and learning difficulties). Off-line information processing and memory consolidation are additional sleep-related benefits.

Mental stimulation: Brain-training, a cognitively challenging lifestyle, novelty, and socialization are vital for the promotion of neuronal plasticity and neurogenesis (the formation of new nerve cells and neuronal connections), the enhancement of specific brain functions such as memory, and the development of cognitive reserve –additional mental processing potential that may be brought online when needed.

The combination of these recommendations, each of which was instrumental in the transformation from primitive to modern nervous systems, provides a template for the most logical approach for enhancing mental function and resisting neurodegeneration as we travel through life.

The Evolutionary Rationale

The human brain clearly has the genetic potential for dramatic expansion. This was illustrated about Read the rest of this entry »

Update: we now have an in-depth interview with Yaakov Stern, leading advocate of the cognitive reserve theory, and one of the authors of the paper we review below: click on Build Your Cognitive Reserve-Yaakov Stern. 

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In honor of the Week of Science presented at Just Science from Monday, February 5, through Sunday, February 11, we will be writing about “just science” this week. We thought we would take this time to discuss more deeply some of the key scientific publications in brain fitness.

Today, we will highlight the key points in an excellent review of cognitive reserve: Scarmeas, Nikolaos and Stern, Yaakov. Cognitive reserve and lifestyle. Journal of Clinical and Experimental Neuropsychology. 2003;25:625-33.

What is Cognitive Reserve?
The concept of a cognitive reserve has been around since 1998 when a post mortem analysis of 137 people with Alzheimer’s Disease showed that the patients exhibited fewer clinical symptoms than their actual pathology suggested. (Katzman et al. 1988) They also showed higher brain weights and greater number of neurons when compared to age-matched controls. The investigators hypothesized that the patients had a larger “reserve” of neurons and abilities that offset the losses caused by Alzheimer’s. Since then the concept of cognitive reserve has been defined as the ability of an individual to tolerate progressive brain pathology without demonstrating clinical cognitive symptoms.
Read the rest of this entry »