Concussion effect ’spans decades’ (BBC)

- “People concussed in their youth show subtle signs of mental and physical problems even more than 30 years later, say Canadian researchers.”

- “Dr Louis de Beaumont, who led the study, said: “This study shows that the effects of sports concussions in early adulthood persist beyond 30 years post-concussion, and that it can cause cognitive and motor function alterations as the athletes age.”

- “Athletes should be better informed about the cumulative and persistent effects of sports concussion on mental and physical processes so they know about the risk associated with returning to their sport.”

The study in question:

De Beaumont L, Theoret H, Mongeon D at al. Brain function decline in healthy retired athletes who sustained their last sports concussion in early adulthood. Brain 2009, Advanced online publication January 27

Given the importance of this topic, which we covered in our 2008 Market Research, we are happy to read about new resources like a new book titled Sports Neuropsychology: Assessment and Management of Traumatic Brain Injury

From a recent book review by Gary S. Solomon, Ph.D.:

- “The past 15 years has yielded an explosion of information on Read the rest of this entry »

Here you have several recent articles and developments worthy of attention:

1) Boom times for brain training games (CNN)
2) Navigating the brain fitness landscape: do’s and don’ts (McKnight’s Long Term Care News)
3) USA Hockey and Intelligym (press release)
4) Brain Fitness at New York Public Library (NYPL blog)
5) McDonnell Foundation grant harnesses cognitive science to improve student learning (press release)
6) Health insurance firms offering online cognitive therapy for insomnia (Los Angeles Times)
7) HeadMinder Cognitive Stability Index: Computerized Neurocognitive … (Press release)
THE AGE OF MASS INTELLIGENCE (Intelligent Life)
9) Working Later in Life May Facilitate Neural Health (Cerebrum)
10) The Cool Factor: Never Let Them See You Sweat (New York Times)

Links, selected quotes and commentary: Read the rest of this entry »

Just saw a very interesting press release regarding computer-based neurocognitive assessments – a critical part of the brain fitness puzzle. How long will it take before consumers can have access to a reliable and credible annual “mental check-up”/ cognitive baseline?

HeadMinder Cognitive Stability Index: Computerized Neurocognitive … (Press release)

- “The HeadMinder web-based Cognitive Stability Index (CSI) has proven more useful for blast-concussion detection than the ANAM computerized test battery the DoD currently employs. The CSI provides an immediate solution to clear the backlog of 400,000 IED-exposed service members in less than two years.”

- “The CSI is a 30-minute, Internet-based, computerized test that provides automated, objective measures of attention, memory, response speed, and processing speed for initial evaluation of cognitive functioning. The CSI produces standardized reports that enable triage and decision-making appropriate to a user’s qualifications – from medic to neuropsychologist to neurologist and other treatment team members.”

We covered this emerging type of assessments in the article Computerized Cognitive Assessments: opportunities and concerns

- “In fact, one of the Read the rest of this entry »

As you have probably seen, the Cognitive Health and Brain Fitness field is rapidly evolving, so let me highlight some of the main recent developments affecting the field:

1) Public policy initiatives:
- The Government of Ontario, Canada, announced a $10m investment in Baycrest Research Center to help develop and commercialize brain fitness technologies. This $10m investment was matched with an additional $10m by local investors.
- In the US, The Paul Wellstone and Pete Domenici Mental Health Parity and Addiction Equity Act of 2008 was signed into law, included in the recently-approved economic bailout bill. The passage of this law has significant implications for healthcare providers and technology vendors alike.

2) Computerized Cognitive Assessments Used by the US Military:
The US Army launched a new policy requiring cognitive screenings of all soldiers before deployment (in order to better diagnose potential problems such as PTSD and TBI upon return). ANAM was the selected computerized battery of tests.

3) Venture & Angel Fundraising for Cognitive Training companies:
A number of developers have raised money. CogniFit received $5m (from Milk Capital), Lumos Labs $3m (FirstMark Capital -previously called Pequot Ventures-, Norwest Venture Partners), Scientific Brain Training $1.5m (issued shares), Vivity Labs $1m (undisclosed angel investors), This is, of course, on top of the February $10.6 investment in Dakim (Galen Partners) that we already included in our market report.

4) Major Initiatives by Insurance Companies:
- Allstate launched a large-scale research project to measure impact of Posit Science InSight (visual processing training) on driver safety for adults over 50.
- OptumHealth announced a 3-year, $18m agreement with Brain Resource to offer web-based cognitive assessments as part of clinicians’ decision support systems.
- Humana decided not to renew its agreement with Posit Science to offer Posit’s auditory processing training program to Medicare members.

5) New Research:
- In a significant new study, a team from the University of Michigan published a high-quality paper in the Proceedings of the National Academy of Sciences showing how computerized working memory training can generalize and improve fluid intelligence (one of the domains that tends to decline with age).
- Learning and Teaching Scotland released an internal study showing how Nintendo Brain Training can help children’s math and concentration skills. The study gained significant media attention, despite the fact it hasn’t been published in a respected journal.

Note: This is an excerpt from the 6-Month Market Update we will  release later this month, covering the many important developments that have occurred since we launched the inaugural Brain Fitness Market Report in March this year. This special report will be available exclusively for our Premium Research Sponsors.

You know your weight. And your physical fitness. And a variety of health-related metrics.

What about your brain fitness?

Two recent announcements bring out how the assessment of cognitive abilities, or brain functions, is increasingly being done thanks to new computerized options:

1) Last week, OptumHealth announced an exclusive 3-year agreement (estimated at $18m) with the Australian company Brain Resource. OptumHealth will be embedding the Brain Resource platform into their overall Behavioral Solutions program.

- OptumHealth Behavioral Solutions will work with Brain Resource to provide clinicians with a Web-based assessment that measures general cognition (how people process information) and social cognition (how people manage their emotions). This 40-minute assessment is based on well-known and validated tests of memory, attention, executive function, and response speed, and mood, social skills and emotional resilience.

Read the rest of this entry »

July is shaping up to be a fascinating month, full of cognitive health research reports and applications. Here you have a roundup, covering food for the brain, cognitive assessments, mental training and DNA, and more.

1) Brain foods: the effects of nutrients on brain function (Nature Neuroscience)

The Aspen Health Forum gathered an impressive group of around 250 people to discuss the most pressing issues in Health and Medical Science (check out the Program and the Speakers bios), on October 3-6th. It was the first conference, by the way, where I have heard a speaker say: “I resuscitated a woman yesterday”.

Key highlights and trends:

1- Global health problems require the attention of the scientific community. Richard Klausner encouraged the scientific community to focus on Global Problems: maternal mortality rates, HIV/ AIDS, nutrition, cancer, clean water.  Bill Frist, former Senate Majority Leader, added to that list the increasing epidemic risks of global zootic diseases (transmitted between humans and animals), supported by 2 interesting data points: at any one moment, there are 500,000 people flying worldwide; in a year, airlines transport the equivalent of 2 billion passengers.

2- “Let’s get real…Ideology kills”. Mary Robinson, former President of Ireland, on what it takes to stop HIV/ AIDS: “I am from Ireland, a Catholic country. And I am Catholic. But I can see how ideology kills..we need more empathy with reality, and to work with local women in those countries who need things like female condoms.” She was implicitly criticizing the large budget devoted to unrealistic abstinence programs. This session included a fascinating exchange where Bill Frist rose from the audience to defend the role of US aid, explaining how 60% of retroviral drugs in African countries have been funded by the American taxpayer, highlighting President Bush’s courage to make HIV/AIDS a top agenda item in many developing countries, and criticizing other countries for not doing enough. Which made Nobel Prize Laureate Peter Agre, also in the audience, stand up and encourage the US to really step up to the plate and devote 1% of the GDP to aid, as a number of European countries do, instead of 0.1%.

3- Where is the new “Sputnik”?: Basic science is crucial for innovation and for economic growth, but it is often underappreciated. Scientists are not “nerds”, as sometimes they are portrayed in popular culture, but people with a deep curiosity and drive to solve a Big problem. Many of the speakers had been inspired by the Sputnik and the Apollo missions to become scientists, at a time when the profession was considered cool. Two Nobel Prize Laureates (Peter Agre, Michael Bishop), talked about their lives and careers trying to demystify what it takes to be a scientist and to win a Nobel Prize. Both are grateful to the taxpayers dollars that funded their research, and insist we must do a better job at explaining the scientific process to society at large. Both are proud of having attended small liberal arts colleges, and having evolved from there, fueled by their great curiosity and unpredictable, serendipitous paths, into launching new scientific and medical fields.  Bishop listed a number of times where he made decisions that were considered “career suicide” by mentors and colleagues, and mentioned “I was confused” around 15 times in 15 minutes…down to earth and inspiring.

4- We need a true Health Care Culture: Mark Ganz summarized it best by explaining how his health provider group improved care when they redefined themselves from “we are 7,000 employees” to “we are a 3 million strong community”, moving from Read the rest of this entry »