Here you have the March edi­tion of our monthly newslet­ter cov­er­ing cog­ni­tive health and brain fit­ness top­ics. Please remem­ber that you can sub­scribe to receive this Newslet­ter by email, using the box at the top of this page. I know I am biased — but do believe this Newslet­ter issue might well be our best so far. I hope you find the time to enjoy it!

Bird’s Eye View

Brain Fit­ness Sur­vey: Over 2,000 thought­ful responses to our Jan­u­ary sur­vey (Thank You!) rein­force the need for pub­lic aware­ness ini­tia­tives and qual­ity infor­ma­tion to help eval­u­ate and nav­i­gate lifestyle and prod­uct claims, as well as the need for more research, an expanded health­care cul­ture, as more. Given this con­text, we are pub­lish­ing The Sharp­Brains Guide to Brain Fit­ness in May 2009, a book with 18 Inter­views with Sci­en­tists, Prac­ti­cal Advice, and Prod­uct Reviews, in addi­tion to our annual mar­ket report for pro­fes­sion­als and exec­u­tives (to be pub­lished in April). If you have ideas to help us pro­mote the book, please reply to this email and let us know!

Life­long Learning

There’s such a flood of very sig­nif­i­cant research stud­ies, edu­ca­tional resources and arti­cles related to brain health, it’s hard to keep track — even for us!

Let me intro­duce and quote some of the top Brain Health Stud­ies, Arti­cles and Resources pub­lished in March:

1) Cog­ni­tive Decline Begins In Late 20s, Study Sug­gests (Sci­ence Daily)

- “These pat­terns sug­gest that some types of men­tal flex­i­bil­ity decrease rel­a­tively early in adult­hood, but that how much knowl­edge one has, and the effec­tive­ness of inte­grat­ing it with one’s abil­i­ties, may increase through­out all of adult­hood if there are no patho­log­i­cal dis­eases,” Salt­house said.

- How­ever, Salt­house points out that there is a great deal of vari­ance from per­son to person

2) Cere­brum 2009: Emerg­ing Ideas in Brain Sci­ence — new book by the Dana Foun­da­tion that “explores the cut­ting edge of brain research and its impli­ca­tions in our every­day lives, in lan­guage under­stand­able to the gen­eral reader.”

A cou­ple of excel­lent chap­ters of direct rel­e­vance to everyone’s brain health are:
– Chap­ter 4: A Road Paved by Rea­son, by Eliz­a­beth Nor­ton Lasley

- Chap­ter 10: Neural Health: Is It Facil­i­tated by Work Force Par­tic­i­pa­tion?, by Denise Park, Ph.D

3) Stay­ing Sharp DVD Pro­gram: “Dr. Jor­dan Graf­man, chief of the Cog­ni­tive Neu­ro­science Sec­tion at the National Insti­tute of Neu­ro­log­i­cal Dis­or­ders and Stroke out­side of Wash­ing­ton, DC, and a mem­ber of the Dana Alliance for Brain Ini­tia­tives, is your guide as we cover what to expect from the aging brain and what we can do to ‘stay sharp.’

For a free DVD of this pro­gram you can con­tact stayingsharp@dana.org. (they say free in their web­site, I don’t know if that includes ship­ping & handling)

4) Dri­vers to be tested on cog­ni­tive abil­ity start­ing at age 75 (Japan Times)

The out­line of a cog­ni­tive test that dri­vers aged 75 or over will be required to take from June when renew­ing their licenses was released Thursday…The test is intended to reduce the num­ber of traf­fic acci­dents involv­ing elderly dri­vers by mea­sur­ing their cog­ni­tive level.

5) Phys­i­cal Fit­ness Improves Spa­tial Mem­ory, Increases Size Of Brain Struc­ture (Sci­ence Daily)

- “Now researchers have found that elderly adults who are more phys­i­cally fit tend to have big­ger hip­pocampi and bet­ter spa­tial mem­ory than those who are less fit.”

6) Brain Train­ers: A Work­out for the Mind (Sci­en­tific Amer­i­can Mind)

“I recently tried out eight of the lat­est brain fit­ness pro­grams, train­ing with each for a week. The pro­grams ranged widely in focus, qual­ity and how fun they were to use. “Like phys­i­cal exer­cise equip­ment, a brain exer­cise pro­gram doesn’t do you any good if you don’t use it, says Andrew J. Carle, direc­tor of the Pro­gram in Assisted Living/Senior Hous­ing Admin­is­tra­tion at George Mason Uni­ver­sity. And peo­ple tend not to use bor­ing equip­ment. “I remem­ber when Nor­dic­Track was the biggest thing out there. Every­one ran out and bought one, and 90 per­cent of them ended up as a clothes rack in the back of your bedroom.

The reporter used: Posit Science’s Brain Fit­ness Pro­gram Clas­sic, Hap­pyNeu­ron, Nin­tendo BrainAge, CogniFit’s MindFit/ Cog­niFit Per­sonal Coach, Lumos­ity, MyBrain­Trainer, Brain­Twister, Cogmed Work­ing Mem­ory Training.

7) The Lat­est in Men­tal Health: Work­ing Out at the ‘Brain Gym’ (Wall Street Journal)

- “Mar­shall Kahn, an 82-year-old fam­ily doc­tor in Fuller­ton, Calif., says he got such a boost from brain exer­cises he started doing at a “Nifty after Fifty” club that he decided to start see­ing patients again part-time. “Doing all the men­tal exer­cise,” he says, “I real­ized I’ve still got it.”

Debate Over Drugs For ADHD Reignites (Wash­ing­ton Post)

- “New data from a large fed­eral study have reignited a debate over the effec­tive­ness of long-term drug treat­ment of chil­dren with hyper­ac­tiv­ity or attention-deficit dis­or­der, and have drawn accu­sa­tions that some mem­bers of the research team have sought to play down evi­dence that med­ica­tions do lit­tle good beyond 24 months.”

- “The study also indi­cated that long-term use of the drugs can stunt children’s growth.”

Adap­tive train­ing leads to sus­tained enhance­ment of poor work­ing mem­ory in chil­dren (Devel­op­men­tal Science)

Abstract: Work­ing mem­ory plays a cru­cial role in sup­port­ing learn­ing, with poor progress in read­ing and math­e­mat­ics char­ac­ter­iz­ing chil­dren with low mem­ory skills. This study inves­ti­gated whether these prob­lems can be over­come by a train­ing pro­gram designed to boost work­ing mem­ory. Chil­dren with low work­ing mem­ory skills were assessed on mea­sures of work­ing mem­ory, IQ and aca­d­e­mic attain­ment before and after train­ing on either adap­tive or non-adaptive ver­sions of the pro­gram. Adap­tive train­ing that taxed work­ing mem­ory to its lim­its was asso­ci­ated with sub­stan­tial and sus­tained gains in work­ing mem­ory, with age-appropriate lev­els achieved by the major­ity of chil­dren. Math­e­mat­i­cal abil­ity also improved sig­nif­i­cantly 6 months fol­low­ing adap­tive train­ing. These find­ings indi­cate that com­mon impair­ments in work­ing mem­ory and asso­ci­ated learn­ing dif­fi­cul­ties may be over­come with this behav­ioral treatment.

9) Brain cor­tex thin­ning linked to inher­ited depres­sion (Los Ange­les Times)

- “On aver­age, peo­ple with a fam­ily his­tory of depres­sion appear to have brains that are 28% thin­ner in the right cor­tex — the out­er­most layer of the brain — than those with no known fam­ily his­tory of the dis­ease. That cor­ti­cal thin­ning, said the researchers, is on a scale sim­i­lar to that seen in patients with Alzheimer’s dis­ease or schizophrenia.”

While trav­el­ling to sev­eral con­fer­ences recently, I real­ized how con­ve­nient it is to post quick updates and thoughts via Twitter.

I will con­tinue to do so often, so you may want to fol­low my Twit­ter Sharp­Brains updates and engage in a con­ver­sa­tion there.

URL is http://twitter.com/AlvaroF

What started as an aca­d­e­mic dis­pute regard­ing dis­clo­sure of con­flict of inter­est is now snow­balling into the main­stream media, due to the over-reaction by JAMA edi­tors as reported in this Wall Street Jour­nal blog post, JAMA edi­tor calls Critic a “Nobody and a Noth­ing”

In sum­mary, Dr. Jonathan Leo, the “Critic”, dared to draw atten­tion to 2 impor­tant points regard­ing a study com­par­ing the effi­cacy of ther­apy vs. med­ica­tion pub­lished in the Jour­nal of the Amer­i­can Acad­emy of Med­i­cine (JAMA) — one of the most pres­ti­gious sci­en­tific publications:

1) The study results were pre­sented and reported in a biased way, since they favored one spe­cific inter­ven­tion, a drug, while ignor­ing another one, therapy-based, that had equally sta­tis­ti­cally sig­nif­i­cant effects.

2) Both the lead author of the study and one of the main experts asked to com­ment on the study in sev­eral media out­lets had undis­closed and unre­ported con­flicts of inter­est. JAMA could have done a 5-minute Google search to iden­tify and report the con­flict of inter­est of the lead author (received a vari­ety of rev­enues from the drugmaker).

Dr. Leo has sum­ma­rized the con­tin­u­ing mat­ter in sev­eral impres­sive let­ters. The 2 main ones, in chrono­log­i­cal order:

Clin­i­cal Tri­als of Ther­apy vs. Med­ica­tion: Even in a Tie, Med­ica­tion Wins(BMJ)

- “Cen­tral to the idea of evidence-based med­i­cine is that the choices made by patients and doc­tors to use a cer­tain treat­ment should at least in part be based on sci­en­tific stud­ies pub­lished in peer reviewed aca­d­e­mic jour­nals. For a patient diag­nosed with Read the rest of this entry »

A per­son who helped rein­vent “aging”, “retire­ment” and “learn­ing”, con­tribut­ing to the cog­ni­tive health of mil­lions of indi­vid­u­als as a result:

Mar­tin P. ‘Marty’ Knowl­ton dies at 88; co-founder of Elder­hos­tel (Los Ange­les Times)

- “Mar­tin P. “Marty” Knowl­ton, a world trav­eler who fought ageism by co-founding Elder­hos­tel, a pro­gram that pio­neered learn­ing vaca­tions for mature adults, has died. He was 88.”

- “Knowl­ton died Thurs­day of nat­ural causes at a nurs­ing home in Ven­tura, said David Bianco, who started Elder­hos­tel with his friend in 1975.”

- “When he was about 50, Knowl­ton became highly annoyed by two things: the pre­vail­ing wis­dom that “as you got older, your mind auto­mat­i­cally began to fail” and the gov­ern­ment noti­fy­ing him that “old age begins at 55,” he told the Ven­tura County Star in 2000.”

The arti­cle: Here

Elder­hos­tel web­site: Here

(Editor’s note: one of the most com­mon ene­mies of get­ting qual­ity cog­ni­tive exer­cise is being on “men­tal autopi­lot”. I recently came across an excel­lent new book, titled The Daily Trad­ing Coach: 101 Lessons for Becom­ing Your Own Trad­ing Psy­chol­o­gist, by trad­ing per­for­mance expert Dr. Brett Steen­barger, which explic­itly calls for address­ing the “men­tal autopi­lot” prob­lem in his Les­son 4. Even for those of us who are not traders, Dr. Steen­barger advice pro­vides excel­lent guid­ance for peak cog­ni­tive per­for­mance. Dr. Steen­barger gra­ciously gave us per­mis­sion to share with you, below, Les­son 4: Change Your Envi­ron­ment, Change Your­self. Enjoy!).

Human beings adapt to their envi­ron­ments. We draw on a range of skills and per­son­al­ity traits to fit into var­i­ous set­tings. That is why we can behave one way in a social set­ting and then seem like a totally dif­fer­ent human being at work. One of the endur­ing attrac­tions of travel is that it takes us out of our native envi­ron­ments and forces us to adapt to new peo­ple, new cul­tures, and new ways. When we make those adap­ta­tions, we dis­cover new facets of our­selves. As we’ll see shortly, dis­crep­ancy is the mother of all change: when we are in the same envi­ron­ments, we tend to draw upon the same, rou­tine modes of thought and behavior.

A few months ago I had an attack of acute appen­dici­tis while stay­ing in a LaGuardia air­port hotel await­ing a return flight to Chicago. When I went to the near­est emer­gency room at Elmhurst Hos­pi­tal out­side Jack­son Heights, Queens, I found that I was seem­ingly the only native Eng­lish speaker in a sea of peo­ple await­ing med­ical care. After some dif­fi­culty attract­ing atten­tion, I was admit­ted to the hos­pi­tal and spent the next sev­eral days of recu­per­a­tion nav­i­gat­ing my way through patients and staff of every con­ceiv­able nation­al­ity. By the end of the expe­ri­ence, I felt at home there. I’ve since stayed at the same air­port hotel and rou­tinely make vis­its into the sur­round­ing neighborhoods—areas I would have never in my wildest dreams ven­tured into pre­vi­ously. In adapt­ing to that envi­ron­ment, I dis­cov­ered hid­den strengths. I also over­came more than a few hid­den prej­u­dices and fears.

The great­est enemy of change is rou­tine. When we lapse into rou­tine and oper­ate on autopi­lot, we are no longer fully and actively con­scious of what we’re doing and why. That is why some of the most fer­tile sit­u­a­tions for per­sonal growth—those that occur within new environments—are those that force us to exit our rou­tines and actively mas­ter unfa­mil­iar challenges.

In famil­iar envi­ron­ments and rou­tines, we oper­ate on autopi­lot. Noth­ing changes.

When you act as your own trad­ing coach, your chal­lenge is to stay fully con­scious, alert to risk and oppor­tu­nity. One of your great­est threats will be the autopi­lot mode in which you act with­out think­ing, with­out full aware­ness of your sit­u­a­tion. If you shift your trad­ing envi­ron­ment, you push your­self to adapt to new sit­u­a­tions: you break rou­tines. If your envi­ron­ment is always the same, you will find your­self grav­i­tat­ing to the same Read the rest of this entry »

Phys­i­cal Fit­ness Improves Spa­tial Mem­ory, Increases Size Of Brain Struc­ture (Sci­ence Daily)

- “Now researchers have found that elderly adults who are more phys­i­cally fit tend to have big­ger hip­pocampi and bet­ter spa­tial mem­ory than those who are less fit.”

- “Cer­tain activ­i­ties are believed to mod­ify hip­pocam­pus size in humans. For exam­ple, a study of Lon­don taxi dri­vers found that the pos­te­rior por­tion of the hip­pocam­pus was larger in expe­ri­enced taxi dri­vers than in other sub­jects. And a study of Ger­man med­ical stu­dents found that the same region of the hip­pocam­pus increased in size as they stud­ied for their final exams.”

- “Stud­ies also have found that the hip­pocam­pus shrinks with age, a process that coin­cides with small but sig­nif­i­cant cog­ni­tive declines. The rate at which this occurs, how­ever, dif­fers among individuals.”

Related arti­cles:

Phys­i­cal Exer­cise and Brain Health

Brain Plas­tic­ity: How learn­ing changes your brain

If you sub­scribe to our monthly newslet­ter, you may remem­ber we ran a sur­vey in Jan­u­ary. Well, the response rate and the qual­ity of the responses were noth­ing short of spec­tac­u­lar, in many dimen­sions. The responses from over 2,000 par­tic­i­pants (out of 21,000 sub­scribers) rein­force the need for pub­lic aware­ness ini­tia­tives and qual­ity infor­ma­tion to help eval­u­ate and nav­i­gate prod­uct claims.

I have been pre­sent­ing the results from one of the ques­tions (see below), yes­ter­day at the ASA/ NCOA (Amer­i­can Soci­ety on Aging) event, today at IHRSA (Inter­na­tional Health, Rac­quet and Sports­club Asso­ci­a­tion), as part of more com­pre­hen­sive pre­sen­ta­tions of what is going on in the brain fit­ness and cog­ni­tive health field.

An obvi­ous impli­ca­tion for the sur­vey result rein­forces the need for brain-related pub­lic aware­ness cam­paigns such as the ongo­ing Brain Aware­ness Week. Every year, land­mark research find­ings open new oppor­tu­ni­ties to help main­tain life­long cog­ni­tive health and brain fit­ness. The oppor­tu­nity is immense — but we will need to ensure the mar­ket­place matures in a ratio­nal and sus­tain­able man­ner, help­ing con­sumers and pro­fes­sion­als sep­a­rate hope from hype and make informed decisions.

Robin Klaus, Chair­man of Club One Fit­ness Cen­ters (the com­pany is a client, he is an advi­sor), just gave us a nice quote say­ing that “as our pop­u­la­tion ages the fields of phys­i­cal fit­ness and brain fit­ness will nat­u­rally merge and, as this hap­pens, a whole new field of val­ued added ser­vices will emerge for our mem­bers. High qual­ity infor­ma­tional resources such as Sharp­Brains’ are cru­cial to the suc­cess of this merger.”

The Sur­vey: Results to Key Question

Asked, “What is the most impor­tant prob­lem you see in the brain fit­ness field and how do you think it can be solved?” respon­dents iden­ti­fied the fol­low­ing six prob­lems in rank order:

#1: Pub­lic Aware­ness (39%)
– “Get­ting peo­ple to under­stand that hered­ity alone does not decide brain func­tion­ing.“
– “An expec­tant pub­lic will first want to believe that a “mir­a­cle” drug is to be soon avail­able (to pre­vent Alzheimer’s Disease).”

#2: Nav­i­gat­ing Claims (21%)
- “How to sep­a­rate mar­ket­ing hype from stuff that really works?“
– “The lack of stan­dards and clear def­i­n­i­tions is very con­fus­ing, and makes a lot of peo­ple sceptical.”

#3: Research (15%)
– “Deter­min­ing what activ­i­ties are most ben­e­fi­cial to Read the rest of this entry »

Reminder:  2009 Brain Aware­ness Week started today. You can find excel­lent resources and a cal­en­dar of events, Here.

Next time you are in a pub­lic space (per­haps now you are at home, as I am as I write these lines), look left, look in front, look right. Per­haps you can see some­one who would ben­e­fit from the aware­ness that he or she is endowed with  that won­der­ful, unique, organ!

(Note: don’t watch TV, or you will spend your day call­ing all those 1–800 numbers…)

And, of course, what a bet­ter week to read some of our Neu­ro­science Inter­views, dis­cover a new brain book, and try a Brain Teaser?

Increased longevity has gen­er­ated many ques­tions and much inter­est in healthy aging and retire­ment lifestyles over the recent decades. As Amer­i­cans become edu­cated regard­ing lifestyle choices that con­tribute to both phys­i­cal and men­tal health, the def­i­n­i­tion of healthy aging has expanded to include brain health.

The notion of retire­ment as a time of with­drawal from soci­ety, to be spent on rest and repose reflected the think­ing of a pre­vi­ous era when peo­ple expected shorter life spans. It is now known that the human brain ben­e­fits from envi­ron­ments rich in novel and com­plex stim­uli, and that by actively par­tic­i­pat­ing in soci­ety and tak­ing on per­son­ally rel­e­vant roles, peo­ple find mean­ing and pur­pose, which gives them a rea­son to get up in the morn­ing and pur­sue new challenges.

This year, the MetLife Mature Mar­ket Insti­tute pub­lished a research study titled Dis­cov­er­ing What Mat­ters: Bal­anc­ing Money, Med­i­cine and Mean­ing. The study explored how peo­ple rebal­ance their pri­or­i­ties over time and jug­gle var­i­ous com­pet­ing aspects of life includ­ing money, med­i­cine (a metaphor for health) and mean­ing, in order to live the Good Life.  Hav­ing pur­pose was found to Read the rest of this entry »